1. Search Result
Search Result
Results for "

decarboxylase

" in MedChemExpress (MCE) Product Catalog:

94

Inhibitors & Agonists

3

Biochemical Assay Reagents

5

Peptides

31

Natural
Products

30

Recombinant Proteins

21

Isotope-Labeled Compounds

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150637

    Bacterial Infection
    Mab Aspartate Decarboxylase-IN-1 is a potent aspartate decarboxylase (PanD) inhibitor with an IC50 value of 56.3 µM. Mab Aspartate Decarboxylase-IN-1 shows antibacterial activity .
    Mab Aspartate Decarboxylase-IN-1
  • HY-P2825

    TDC; TyrDC

    Endogenous Metabolite Metabolic Disease Cancer
    Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide .
    Tyrosine decarboxylase, Microorganism
  • HY-P2796

    Kp-IpdC

    Others Others
    Pyruvate decarboxylase (Kp-IpdC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Pyruvate decarboxylase
  • HY-N3394

    Others Infection
    Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .
    Lecanoric acid
  • HY-W003445

    Endogenous Metabolite Neurological Disease
    4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes .
    4-Bromo-3-hydroxybenzoic acid
  • HY-E70221

    Others Others
    α-Acetolactate decarboxylase, from Bacillus subtilis is an enzyme responsible for acetoin production, and can be widely used in food processing .
    α-Acetolactate decarboxylase, from Bacillus subtilis
  • HY-P2837

    Endogenous Metabolite Metabolic Disease
    Oxaloacetate decarboxylase catalyzes the irreversible decarboxylation of oxaloacetate to pyruvate and COIC2. Oxaloacetate decarboxylase is a member of the sodium ion transport decarboxylase (NaT-DC) enzyme family. Oxaloacetate decarboxylase converts the chemical energy of the decarboxylation reaction into an electrochemical gradient of Na + ions across the membrane .
    Oxaloacetate decarboxylase
  • HY-E70423

    Biochemical Assay Reagents Others
    UDP-glucuronic acid decarboxylase is a decarboxylase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
    UDP-glucuronic acid decarboxylase
  • HY-164091

    Endogenous Metabolite Metabolic Disease
    Mevalonate 5-phosphate is a substrate of phosphomevalonate kinase and mevalonate-5-phosphate decarboxylase .
    Mevalonate 5-phosphate
  • HY-113305

    Endogenous Metabolite Metabolic Disease
    Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .
    Dopamine 3-O-sulfate
  • HY-N2553

    LPL Receptor Metabolic Disease
    4-Deoxypyridoxine 5'-phosphate is a Pyridoxal 5'-phosphate analogue and a sphingosine 1-phosphate (S1P) inhibitor. 4-Deoxypyridoxine 5'-phosphate inhibits ornithine decarboxylase activity with a Ki of 60 μM. 4-Deoxypyridoxine 5'-phosphate is a competitive inhibitor of the activation of glutamate apodecarboxylase by Pyridoxal 5'-phosphate (Ki of 0.27 μM) and strongly inhibits glutamate-dependent labeling of glutamate decarboxylase .
    4-Deoxypyridoxine 5'-phosphate
  • HY-103355
    YM022
    2 Publications Verification

    CCR Metabolic Disease
    YM022 is a highly potent, selective and orally active gastrin/cholecystokinin (CCK)-B receptor (CCK-BR) antagonist. YM022 shows the Ki values of 68 pM and 63 nM for CCK-B and CCK-A receptor, respectively . YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo .
    YM022
  • HY-132822

    SBP-101

    Others Cancer
    Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers .
    Ivospemin
  • HY-100983

    PKC Cancer
    Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .
    Protein kinase inhibitor H-7 dihydrochloride
  • HY-106634
    Mitoguazone
    1 Publications Verification

    Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG

    HIV Apoptosis Infection Cancer
    Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
    Mitoguazone
  • HY-106634R

    HIV Apoptosis Infection Cancer
    Mitoguazone (Standard) is the analytical standard of Mitoguazone. This product is intended for research and analytical applications. Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
    Mitoguazone (Standard)
  • HY-U00065

    Inhibostamin; Hypostamine

    Others Inflammation/Immunology
    Tritoqualine is used as a histidine decarboxylase inhibitor.
    Tritoqualine
  • HY-133957

    6-Fluoromevalonate; FMev

    Biochemical Assay Reagents Others
    6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor.
    Fluoromevalonate
  • HY-13746

    CGP 48664; SAM-486A

    Others Cancer
    Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
    Sardomozide
  • HY-13746B
    Sardomozide dihydrochloride
    5 Publications Verification

    CGP 48664A

    Others Cancer
    Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
    Sardomozide dihydrochloride
  • HY-Y0367
    Maleic Acid
    1 Publications Verification

    Endogenous Metabolite Bacterial Infection
    Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.
    Maleic Acid
  • HY-B1537

    2',3',5'-Tri-O-acetyl-6-azauridine

    Virus Protease Influenza Virus Infection Inflammation/Immunology
    Azaribine (2',3',5'-Tri-O-acetyl-6-azauridine) is a potent orotidine monophosphate decarboxylase (OMPD) inhibitor. Azaribine is an antiviral inhibitor of several RNA viruses and inhibits viral genome replication and gene transcription. Azaribine shows broad-spectrum antiviral activity (EC50=3.80 nM-1.73 μM against influenza A and B viruses; EC50=1.62 μM against ZIKV Paraiba). Azaribine, a triacetate salt of Azauridine, has the potential for psoriasis research .
    Azaribine
  • HY-122968

    NSD-1065

    Others Neurological Disease
    Brocresine (NSD-1065) is an orally active histidine decarboxylase inhibitor and inhibits the formation of histamine from histidine. Brocresine is also a L-amino acid decarboxylase inhibitor with both a peripheral and central action. Brocresine inhibits gastric secretory response to administration of exogenous gastrin .
    Brocresine
  • HY-W015300

    Octanedioic acid

    Endogenous Metabolite Metabolic Disease
    Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency.
    Suberic acid
  • HY-34740

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid
  • HY-B0404A
    Benserazide hydrochloride
    4 Publications Verification

    Serazide; Ro 4-4602

    Others Neurological Disease
    Benserazide hydrochloride (Serazide) is commonly used in Parkinson's disease and is an inhibitor of peripheral aromatic L-amino acid decarboxylase (AADC) .
    Benserazide hydrochloride
  • HY-N0240
    Herbacetin
    4 Publications Verification

    Others Cancer
    Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .
    Herbacetin
  • HY-B0744
    Eflornithine
    Maximum Cited Publications
    10 Publications Verification

    DFMO; MDL71782; RMI71782; α-difluoromethylornithine

    Parasite Infection Cancer
    Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine
  • HY-B0744A
    Eflornithine hydrochloride
    Maximum Cited Publications
    10 Publications Verification

    DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride

    Parasite Infection Cancer
    Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine hydrochloride
  • HY-W012382

    Endogenous Metabolite Metabolic Disease
    N-Acetyl-L-tyrosine originates from tyrosine through an AA acetylase, is associated with aromatic L-amino acid decarboxylase deficiency and tyrosinemia I.
    N-Acetyl-L-tyrosine
  • HY-N0384

    Vanilacetic acid

    Drug Metabolite Endogenous Metabolite Metabolic Disease
    Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid
  • HY-112619
    TES-991
    1 Publications Verification

    Others Metabolic Disease
    TES-991 is a potent and selective human α‑Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC50 of 3 nM.
    TES-991
  • HY-B0744B
    Eflornithine hydrochloride hydrate
    Maximum Cited Publications
    10 Publications Verification

    DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate

    Parasite Cancer
    Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
    Eflornithine hydrochloride hydrate
  • HY-111365
    TES-1025
    3 Publications Verification

    Others Metabolic Disease
    TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM .
    TES-1025
  • HY-W016729

    Biochemical Assay Reagents Others
    4-(Dimethylamino)cinnamaldehyde is a reagent used for determining indole products of tryptophan decarboxylase and tryptophanase, and can also be used for quantifying proanthocyanidins in cranberry powder.
    4-(Dimethylamino)cinnamaldehyde
  • HY-N0240R

    Others Cancer
    Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .
    Herbacetin (Standard)
  • HY-34740S

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Ethylmalonic acid-d3 is the deuterium labeled Ethylmalonic acid. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid-d3
  • HY-34740S1

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Ethylmalonic acid-d5 is the deuterium labeled Ethylmalonic acid. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid-d5
  • HY-N0575
    Pinocembrin
    5 Publications Verification

    (+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone

    Bacterial Reactive Oxygen Species Autophagy Infection Inflammation/Immunology Cancer
    Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties .
    Pinocembrin
  • HY-N0122
    5-Hydroxytryptophan
    1 Publications Verification

    5-HTP; DL-5-Hydroxytryptophan

    Endogenous Metabolite Metabolic Disease
    5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .
    5-Hydroxytryptophan
  • HY-B0404AS

    Serazide-d3; Ro 4-4602-d3

    Isotope-Labeled Compounds Neurological Disease
    Benserazide-d3 (hydrochloride) is the deuterium labeled Benserazide hydrochloride. Benserazide hydrochloride (Serazide) is commonly used in Parkinson's disease and is an inhibitor of peripheral aromatic L-amino acid decarboxylase (AADC)[1].
    Benserazide-d3 hydrochloride
  • HY-Y0367S

    Maleic-2,3-d2 acid

    Bacterial Endogenous Metabolite Infection
    Maleic Acid-d2 is the deuterium labeled Maleic Acid[1]. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes[2][3].
    Maleic Acid-d2
  • HY-W015300R

    Endogenous Metabolite Metabolic Disease
    Suberic acid (Standard) is the analytical standard of Suberic acid. This product is intended for research and analytical applications. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency.
    Suberic acid (Standard)
  • HY-34740R

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Ethylmalonic acid (Standard) is the analytical standard of Ethylmalonic acid. This product is intended for research and analytical applications. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid (Standard)
  • HY-W016349

    Others Others
    Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
    Chelidamic acid
  • HY-125748

    Others Cardiovascular Disease
    CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases .
    CBM-301940
  • HY-B0404AR

    Serazide (Standard); Ro 4-4602 (Standard)

    Others Neurological Disease
    Benserazide (hydrochloride) (Standard) is the analytical standard of Benserazide (hydrochloride). This product is intended for research and analytical applications. Benserazide hydrochloride (Serazide) is commonly used in Parkinson's disease and is an inhibitor of peripheral aromatic L-amino acid decarboxylase (AADC) .
    Benserazide (hydrochloride) (Standard)
  • HY-W017522

    Drug Metabolite Endogenous Metabolite Metabolic Disease
    Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.
    Adipic acid
  • HY-N0384S2

    Vanilacetic acid-d5

    Endogenous Metabolite Metabolic Disease
    Homovanillic acid-d5 is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d5
  • HY-N0384S

    Vanilacetic acid-d3

    Endogenous Metabolite Metabolic Disease
    Homovanillic acid-d3 is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d3

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: