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Results for "

ehrlich

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (4) Aminopeptidase (1) Antibiotic (8) Apoptosis (5) Autophagy (4) Bacterial (8) Bcl-2 Family (1) Biochemical Assay Reagents (2) Carbonic Anhydrase (1) Caspase (1) Cytochrome P450 (1) DNA/RNA Synthesis (7) Fluorescent Dye (1) Fungal (2) HSV (1) Interleukin Related (1) MDM-2/p53 (1) MMP (1) NF-κB (1) NO Synthase (1) Reactive Oxygen Species (1) Topoisomerase (4) VEGFR (1)
By Research Areas:	Cancer (21) Infection (11) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (5)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0085

DiSC3(5) 5 Publications Verification	Fluorescent Dye	Others
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

HY-Y0015

p-Dimethylaminobenzaldehyde 4-Dimethylaminobenzaldehyde	Biochemical Assay Reagents	Others
p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles .

HY-19459A

Ocaphane free acid AT-581 free acid	Others	Cancer
Ocaphane (free acid) is an antitumor agent that inhibits tumor growth in the Ehrlich tumor mouse model .

HY-136110

2-Keto-D-galactose D-Galactosone	DNA/RNA Synthesis	Cancer
2-Keto-D-galactose (D-Galactosone) inhibits DNA synthesis, and inhibits proliferation of in vitro grown Ehrlich ascites tumor cells .

HY-129762

Yoshi-864 NSC-102627	DNA/RNA Synthesis	Cancer
Yoshi-864 is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor .

HY-121794

Avarol (+)-Avarol	Others	Cancer
Avarol is a sesquiterpene hydroquinone that can be isolated from Dysidea avara sponge. Avarol has the potential for the research of ehrlich carcinoma (EC) and cervical cancer (CC-5) .

HY-19606

Cytogenin Antibiotic MI 43-37F11	Interleukin Related NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model .

HY-118327

Maleuric acid N-carbamylmaleamic acid	Others	Cancer
Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis^[1].

HY-126617

Duclauxin NSC 258308	Others	Cancer
Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin (10-30 μg/mL) inhibits mitochondrial respiration of P-388 tumor cells and nucleic acid synthesis in cell culture of Ehrlich cancer, the lymphadenomas NK/LI and L 5178, and sarcoma 37. Duclauxin also inhibits growth of wheat coleoptile.

HY-119589

Altersolanol B Dactylarin	Others	Others
Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells.

HY-126699

Herbimycin C Antibiotic TAN 420D	Others	Infection
Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC₅₀s=7.3 and 1.2 μg/mL, respectively).

HY-Y0015R

p-Dimethylaminobenzaldehyde (Standard)	Biochemical Assay Reagents	Others
p-Dimethylaminobenzaldehyde (Standard) is the analytical standard of p-Dimethylaminobenzaldehyde. This product is intended for research and analytical applications. p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles .

HY-19839

Ansamitocin P 3' Antibiotic C 15003P3'; Maytansinol butyrate	Antibiotic	Infection Cancer
Ansamitocin P 3' (Antibiotic C 15003P3') is an anti-tumor antibiotic. Ansamitocin P 3' prolongs the survival of mice with leukemia P388, melanoma B16, leukemia L1210, sarcoma 180, Ehrlich carcinoma and mast cell tumor P815 .

HY-119789

Albofungin	Antibiotic Bacterial	Infection
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.

HY-121123

Adamantanine 2-Aminoadamantane-2-carboxylic acid	Aminopeptidase	Cancer
Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (K_i is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC₅₀ of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S_0.5 of 10.5 .

HY-150015

4,5'-Dimethylangelicin-NHS	DNA/RNA Synthesis	Cancer
4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .

HY-126170

Valanimycin	Antibiotic Bacterial	Infection Cancer
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC₅₀ of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .

HY-121245

Capoamycin	Antibiotic Bacterial Fungal	Infection Cancer
Capoamycin is an antibiotic. Capoamycin shows antimicrobial and antitumor activity .

HY-129983

5-Hydroxymethyl-2'-deoxyuridine	HSV	Infection Cancer
5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC₅₀ values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia .

HY-158328A

CA IX/VEGFR-2-IN-2	Carbonic Anhydrase VEGFR Reactive Oxygen Species MDM-2/p53 Bcl-2 Family Cytochrome P450 Caspase	Cancer
CA IX/VEGFR-2-IN-2 (compound 5e) is a dual-targeted inhibitor. CA IX/VEGFR-2-IN-2 shows strong inhibitory effects on both CA IX (K_i=3.1 μM) and VEGFR-2 (IC₅₀=32.1 nM). CA IX/VEGFR-2-IN-2 can be used for the study of pancreatic (PANC1), breast cancer (MCF7) and prostate cancer (PC3) .

HY-137566

Cucumarioside H	Others	Cancer
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

HY-13062

Daunorubicin hydrochloride Maximum Cited Publications 25 Publications Verification Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-13062A

Daunorubicin Daunomycin; RP 13057; Rubidomycin	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-108876

Daunorubicin citrate Daunomycin(citrate); RP 13057(citrate); Rubidomycin(citrate)	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) citrate is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin citrate inhibits DNA and RNA synthesis. Daunorubicin citrate is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin citrate is also an anthracycline antibiotic. Daunorubicin citrate can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-13062R

Daunorubicin hydrochloride (Standard)	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic	Infection Neurological Disease Cancer
Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-B0900

Anethole 1 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Apoptosis Fungal Bacterial MMP NF-κB	Infection Neurological Disease Inflammation/Immunology Cancer
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

Cat. No.	Product Name	Type

HY-D0085

DiSC3(5) 5 Publications Verification	Fluorescent Dyes/Probes
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

DiSC3(5)

5 Publications Verification

Fluorescent Dyes/Probes

DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

Cat. No.	Product Name	Target	Research Area

HY-P2045

RA-VII	Peptides	Cancer
RA-VII is an antitumor agent that exhibits significant activity against L1210, B-16 melanoma, Lewis lung carcinoma, Colon 38 and Ehrlich carcinoma .

Daunorubicin hydrochloride Maximum Cited Publications 25 Publications Verification Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Disease Research Fields	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

Anethole 1 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Structural Classification Classification of Application Fields Source classification Plants Microorganisms Simple Phenylpropanols Leguminosae Phenylpropanoids Umbelliferae Vernonia Schreb. Glycyrrhiza uralensis Fisch. Disease Research Fields Cancer	Apoptosis Fungal Bacterial MMP NF-κB
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

Avarol (+)-Avarol	Structural Classification Monophenols Marine natural products Source classification Phenols	Others
Avarol is a sesquiterpene hydroquinone that can be isolated from Dysidea avara sponge. Avarol has the potential for the research of ehrlich carcinoma (EC) and cervical cancer (CC-5) .

Ansamitocin P 3' Antibiotic C 15003P3'; Maytansinol butyrate	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic
Ansamitocin P 3' (Antibiotic C 15003P3') is an anti-tumor antibiotic. Ansamitocin P 3' prolongs the survival of mice with leukemia P388, melanoma B16, leukemia L1210, sarcoma 180, Ehrlich carcinoma and mast cell tumor P815 .

Albofungin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.

Valanimycin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Antibiotic Bacterial
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC₅₀ of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .

Capoamycin	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic Bacterial Fungal
Capoamycin is an antibiotic. Capoamycin shows antimicrobial and antitumor activity .

Cucumarioside H	Triterpenes Structural Classification Animals Terpenoids Source classification	Others
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

Daunorubicin Daunomycin; RP 13057; Rubidomycin	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Disease Research Fields	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

Daunorubicin hydrochloride (Standard)	Quinones Structural Classification Microorganisms Anthraquinones Source classification Phenols Polyphenols	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic
Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

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