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Results for "

fluoroquinolone antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (66) Apoptosis (9) Bacterial (64) DNA/RNA Synthesis (1) Isotope-Labeled Compounds (9) Mitochondrial Metabolism (9) Reactive Oxygen Species (9) Topoisomerase (16)
By Research Areas:	Cancer (10) Infection (65) Inflammation/Immunology (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0147A

Grepafloxacin hydrochloride OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride	Antibiotic Bacterial	Infection
Grepafloxacin (OPC-17116) hydrochloride is an oral actively fluoroquinolone *antibiotic* with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin hydrochloride has high tissue penetration and a promising pharmacodynamic profile .

HY-B0395C

Sitafloxacin hydrate 5 Publications Verification DU6859a hydrate	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .

HY-B0395

Sitafloxacin 5 Publications Verification DU6859a	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone *antibiotic*. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .

HY-17028

Besifloxacin Hydrochloride	Bacterial Antibiotic	Infection
Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.

HY-B0724A

Pazufloxacin mesylate T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate	Bacterial Antibiotic	Infection
Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.

HY-17028A

(Rac)-Besifloxacin hydrochloride	Bacterial Antibiotic	Infection
(Rac)-Besifloxacin hydrochloride is the enantiomer of Besifloxacin hydrochloride. Besifloxacin hydrochloride is a broad-spectrum fourth-generation fluoroquinolone antibiotic .

HY-A0147

Grepafloxacin OPC-17116; dl-Grepafloxacin	Antibiotic Bacterial	Infection
Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone *antibiotic* with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .

HY-B0395CR

Sitafloxacin hydrate (Standard) DU6859a hydrate (Standard)	Bacterial Antibiotic	Infection
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .

HY-B0395B

Sitafloxacin monohydrate DU6859a monohydrate	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone *antibiotic*. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .

HY-B0395A

Sitafloxacin hydrochloride DU6859a hydrochloride	Antibiotic Bacterial	Infection
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone *antibiotic*. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .

HY-B0724B

Pazufloxacin T3761	Bacterial Antibiotic	Infection
Pazufloxacin (T-3761) is a fluoroquinolone antibiotic.

HY-117566

RPR 102341	Antibiotic Bacterial	Infection
RPR 102341 is structurally similar to the fluoroquinolone class of antibiotics .

HY-U00214

Ibafloxacine R835; S25930	Antibiotic Bacterial	Infection
Ibafloxacine (R835) is a fluoroquinolone antibiotic agent that is developed exclusively for veterinary use.

HY-B0506

Nadifloxacin 1 Publications Verification OPC7251	Bacterial Antibiotic	Infection
Nadifloxacin(OPC7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.

HY-B0915

Orbifloxacin 1 Publications Verification CP-104354	Bacterial Antibiotic	Infection
Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic which is approved for use in dogs.

HY-W739930

Desmethyl ofloxacin hydrochloride	Antibiotic	Infection
Desmethyl ofloxacin hydrochloride is a metabolite of the fluoroquinolone antibiotic Ofloxacin (HY-B0125).

HY-B0308

Sparfloxacin CI-978; AT-4140	Bacterial Antibiotic	Infection
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .

HY-B0356AS

Ciprofloxacin-d8 hydrochloride hydrate Bay-09867-dd₈ hydrochloride hydrate	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Ciprofloxacin-d₈ (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0356BS

Ciprofloxacin-d8 hydrochloride monohydrate Bay-09867-d₈ hydrochloride monohydrate	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Ciprofloxacin-d₈ (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0356S

Ciprofloxacin-d8 hydrochloride Bay-09867-d₈ hydrochloride	Bacterial Antibiotic	Infection
Ciprofloxacin-d₈ (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0356S1

Ciprofloxacin-d8 Bay-09867-d₈	Bacterial Antibiotic	Infection
Ciprofloxacin-d₈ is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0308S

Sparfloxacin-d5 CI-978-d₅; AT-4140-d₅	Bacterial Antibiotic Isotope-Labeled Compounds	Infection
Sparfloxacin-d5 is deuterium labeled Sparfloxacin (HY-B0308). Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .

HY-16035

Alatrofloxacin	DNA/RNA Synthesis Antibiotic	Cancer
Alatrofloxacin, the parenteral proagent of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity .

HY-B0506R

Nadifloxacin (Standard)	Bacterial Antibiotic	Infection
Nadifloxacin (Standard) is the analytical standard of Nadifloxacin. This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.

HY-W799435

Tosufloxacin hydrate A-61827 hydrate	Antibiotic Bacterial	Infection
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone *antibiotic*. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-B1802B

Tosufloxacin hydrochloride A-61827 hydrochloride	Antibiotic Bacterial	Infection
Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-B1802C

Tosufloxacin tosylate A-61827 tosylate	Antibiotic Bacterial	Infection
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-B0308R

Sparfloxacin (Standard)	Bacterial Antibiotic	Infection
Sparfloxacin (Standard) is the analytical standard of Sparfloxacin. This product is intended for research and analytical applications. Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .

HY-B1802A

Tosufloxacin tosylate hydrate 2 Publications Verification A-61827 tosylate hydrate; T-3262	Bacterial Antibiotic	Infection
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-B1802

Tosufloxacin A-61827	Antibiotic Bacterial	Infection
Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-B0506S1

Nadifloxacin-d5 OPC7251-d₅	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Nadifloxacin-d₅ (OPC7251-d₅) is deuterium labeled Nadifloxacin. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.

HY-14814

Delafloxacin 2 Publications Verification RX-3341; WQ-3034; ABT492	Bacterial Antibiotic	Infection
Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .

HY-B0159

Balofloxacin Q-35	Bacterial Antibiotic	Infection
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .

HY-B1802CR

Tosufloxacin (tosylate) (Standard)	Antibiotic Bacterial	Infection
Tosufloxacin (tosylate) (Standard) is the analytical standard of Tosufloxacin (tosylate). This product is intended for research and analytical applications. Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-14814A

Delafloxacin meglumine 2 Publications Verification ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine	Bacterial Antibiotic	Infection
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .

HY-B0159A

Balofloxacin dihydrate Q-35 dihydrate	Bacterial Antibiotic	Infection
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections .

HY-B0132B

Norfloxacin (nicotinate) MK-0366 (nicotinate)	Bacterial Antibiotic	Infection
Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration .

HY-14814S

Delafloxacin-d5 RX-3341-d₅; WQ-3034-d₅; ABT492-d₅	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-B0024

Prulifloxacin 2 Publications Verification NM441	Bacterial Antibiotic	Infection
Prulifloxacin (NM441) is an orally active fluoroquinolone *antibiotic* with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis .

HY-14814R

Delafloxacin (Standard)	Bacterial Antibiotic	Infection
Delafloxacin (Standard) is the analytical standard of Delafloxacin. This product is intended for research and analytical applications. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .

HY-B0536

Clinafloxacin AM-1091; CI-960; PD 127391	Bacterial Antibiotic	Infection
Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone *antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase* and topoisomerase IV of?S. aureus with IC₅₀ values of 0.92 μg/ml and 1.62 μg/ml, respectively .

HY-B0356

Ciprofloxacin Maximum Cited Publications 35 Publications Verification Bay-09867	Topoisomerase Apoptosis Antibiotic Bacterial Mitochondrial Metabolism Reactive Oxygen Species	Infection Cancer
Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .

HY-B0356B

Ciprofloxacin hydrochloride monohydrate Maximum Cited Publications 35 Publications Verification Bay-09867 hydrochloride monohydrate	Topoisomerase Apoptosis Antibiotic Bacterial Mitochondrial Metabolism Reactive Oxygen Species	Infection Cancer
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .

HY-B0159R

Balofloxacin (Standard)	Bacterial Antibiotic	Infection
Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .

HY-B0536A

Clinafloxacin hydrochloride AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride	Bacterial Antibiotic	Infection
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone *antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase* and topoisomerase IV of S. aureus with IC₅₀ values of 0.92 µg/ml and 1.62 µg/ml, respectively .

HY-14814AR

Delafloxacin meglumine (Standard) ABT492 meglumine (Standard); RX-3341 meglumine (Standard); WQ-3034 meglumine (Standard)	Bacterial Antibiotic	Infection
Delafloxacin (meglumine) (Standard) is the analytical standard of Delafloxacin (meglumine). This product is intended for research and analytical applications. Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-W040298

Ciprofloxacin lactate Bay-09867 lactate	Topoisomerase Apoptosis Antibiotic Bacterial Mitochondrial Metabolism Reactive Oxygen Species	Infection Cancer
Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .

HY-B0356A

Ciprofloxacin monohydrochloride Maximum Cited Publications 35 Publications Verification Bay-09867 monohydrochloride	Topoisomerase Apoptosis Antibiotic Bacterial Mitochondrial Metabolism Reactive Oxygen Species	Infection Cancer
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .

HY-B0024R

Prulifloxacin (Standard)	Bacterial Antibiotic	Infection
Prulifloxacin (Standard) is the analytical standard of Prulifloxacin. This product is intended for research and analytical applications. Prulifloxacin (NM441) is an orally active fluoroquinolone *antibiotic* with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis .

HY-B0330D

(R)-Ofloxacin Dextrofloxacin	Bacterial Antibiotic	Infection
(R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone *antibiotic*. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1802A

Tosufloxacin tosylate hydrate 2 Publications Verification A-61827 tosylate hydrate; T-3262	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

Cat. No.	Product Name	Chemical Structure

HY-B0356S

Ciprofloxacin-d8 hydrochloride
Ciprofloxacin-d₈ (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0356S1

Ciprofloxacin-d8
Ciprofloxacin-d₈ is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-14814S

Delafloxacin-d5
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-B0356AS

Ciprofloxacin-d8 hydrochloride hydrate
Ciprofloxacin-d₈ (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0356BS

Ciprofloxacin-d8 hydrochloride monohydrate
Ciprofloxacin-d₈ (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

HY-B0308S

Sparfloxacin-d5
Sparfloxacin-d5 is deuterium labeled Sparfloxacin (HY-B0308). Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity .

HY-B0506S1

Nadifloxacin-d5
Nadifloxacin-d₅ (OPC7251-d₅) is deuterium labeled Nadifloxacin. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.

HY-B0395S

Sitafloxacin-d4

Sitafloxacin-d₄ (DU6859a-d₄) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .

HY-10581AS

Gatifloxacin-d3 hydrochloride

Gatifloxacin-d₃ (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.

HY-B0356S2

Ciprofloxacin-d4

Ciprofloxacin-d₄ (Bay-09867-d₄) is deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .

HY-B0330DS

(R)-Ofloxacin-d3

(R)-Ofloxacin-d₃ is the deuterium labeled (R)-Ofloxacin. (R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone antibiotic. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria .

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