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Results for "

formyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Formyl Peptide Receptor (FPR) (30) Akt (1) Amino Acid Derivatives (2) Antibiotic (3) Apoptosis (5) Bacterial (5) Biochemical Assay Reagents (4) Bombesin Receptor (1) Calcium Channel (2) Caspase (2) COX (1) CXCR (1) Cytochrome P450 (2) DNA/RNA Synthesis (1) Drug Metabolite (1) Endogenous Metabolite (4) Fluorescent Dye (1) Fungal (4) Influenza Virus (1) Isotope-Labeled Compounds (4) Lipoxygenase (1) Neurokinin Receptor (1) Nucleoside Antimetabolite/Analog (1) PERK (1) Phosphodiesterase (PDE) (1) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (4) Thymidylate Synthase (1) TNF Receptor (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Infection (14) Inflammation/Immunology (28) Metabolic Disease (7) Neurological Disease (10)
Oligonucleotides:	Nucleosides and their Analogs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

*N-Formyl-Met-Leu-Phe* Maximum Cited Publications 9 Publications Verification fMLP; N-formyl-MLF	TNF Receptor	Inflammation/Immunology
N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

*N-Formyl-MMYALF*	Formyl Peptide Receptor (FPR)	Infection
N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF can inhibit the FPR-1-mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides .

*N-Formyl-Met-Leu-Phe-Lys* fMLFK	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC₅₀s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D281 ^7.32G, respectively .

*N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys* For-Nle-Leu-Phe-Nle-Tyr-Lys-OH	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .

*3-Formyl* rifamycin**	Antibiotic	Infection
3-Formyl rifamycin is an intermediate of Rifampicin.

*5-Formyl-2'-deoxyuridine*	Endogenous Metabolite	Others
5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .

*N-Formyl-MMYALF TFA*	Formyl Peptide Receptor (FPR)	Infection
N-Formyl-MMYALF TFA is a mitochondrial N-formyl peptide that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF TFA can inhibit the FPR-1-mediated chemotactic response of PMNs to bacterial peptides .

*N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA* For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .

*3-Formyl* rifamycin (Standard)**	Antibiotic	Infection
3-Formyl rifamycin (Standard) is the analytical standard of 3-Formyl rifamycin. This product is intended for research and analytical applications. 3-Formyl rifamycin is an intermediate of Rifampicin.

*5-Formyl-dCTP* 5-formyl-deoxycytidine	DNA/RNA Synthesis	Others
5-Formyl-dCTP is a modified nucleotide that can be used for DNA synthesis .

*10-Formyl-7,8-dihydrofolic acid*	Endogenous Metabolite	Metabolic Disease
10-Formyl-7,8-dihydrofolic acid is a substrate for mammalian aminoimidazolecarboxamide ribotide transformylase (EC 2.1.2.3). 10-Formyl-7,8-dihydrofolic acid also is a metabolite of 10-HCO-H4folate .

*10-Formyl-5,8-dideazafolic acid*	Thymidylate Synthase	Cancer
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor .

*N-Formyl* desloratadine**	Biochemical Assay Reagents	Others
N-Formyl Desloratadine is a biological molecule.

*Nε-Formyl-L-lysine*	Amino Acid Derivatives	Others
Nε-Formyl-L-lysine is a lysine derivative .

*1-Formyl-beta-carboline*	Influenza Virus Akt	Infection
1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM, and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway .

*N-Formyl-L-leucine* N-formyl-S-leucine; N-formylleucine; NSC 334321	Amino Acid Derivatives	Others
N-Formyl-L-leucine is a leucine derivative .

*5-Formyl-2’-O-methylcytidine*	Nucleoside Antimetabolite/Analog	Others
5-Formyl-2’-O-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .

Picralinal Picraline, 16-de(acetoxymethyl)-16-formyl-	COX Lipoxygenase	Others
Picralinal (Picraline, 16-de(acetoxymethyl)-16-formyl-) is a Triterpenoids product that can be isolated from the whole plants of Scilla scilloides. .

*6-Formyl-isoophiopogonanone A*	Others	Inflammation/Immunology
6-Formyl-isoophiopogonanone A is a homoisoflavonoidal extracted from Ophiopogon japonicas, with antioxidant activity .

*6-Formyl-isoophiopogonanone B*	Others	Others
6-Formyl-isoophiopogonanone B is a homoisoflavonoid, which can be isolated from Ophiopogon japonicus .

*1-Ethyl-4-formyl-1h-pyrrole-2-carbonitrile*	Biochemical Assay Reagents
1-Ethyl-4-formyl-1h-pyrrole-2-carbonitrile is a biochemical reagent .

AG-09/1	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense .

(+)-N-Formylnorglaucine	Others	Others
(+)-N-Formylnorglaucine is an aporphine alkaloid isolated from the leaves of Unonopsis stipitata. (+)-N-Formylnorglaucine contains a formyl group linked to the heterocyclic nitrogen .

{Boc}-Phe-Leu-Phe-Leu-Phe TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
{Boc}-Phe-Leu-Phe-Leu-Phe TFA is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor .

{Boc}-Phe-Leu-Phe-Leu-Phe	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor .

*6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine*	Others	Others
6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine is a Alkaloids product that can be isolated from the aerial parts of Aconitum carmichaelii. .

*2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde*	Others	Others
2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde is a natural product .

QWF Peptide	Neurokinin Receptor	Neurological Disease
QWF Peptide (Compound 4a) is a substance P antagonist with an IC₅₀ of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC₅₀ of 4.7 μM .

10-Formyltetrahydrofolic acid	Endogenous Metabolite	Metabolic Disease
10-Formyltetrahydrofolic acid is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines .

10-Formyltetrahydrofolic acid disodium	Endogenous Metabolite	Metabolic Disease
10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines .

FPR Agonist 43 2 Publications Verification	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist .

Boc-MLF TFA 3 Publications Verification Boc-Met-Leu-Phe-OH TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations .

A-71497	Antibiotic	Infection
A-71497 is the 3-formyl derivative of the antibiotic Tosufloxacin (HY-B1802). A-71497 can produce high plasma levels of tosufloxacin upon both oral and subcutaneous administration to mice .

8-Hydroxyjulolidine	Fluorescent Dye	Others
8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .

MMK1	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 is a potent and selective *human formyl* peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing** agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity .

MMK1 TFA	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 TFA is a potent and selective *human formyl* peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing** agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity .

LAB 149202F	Bacterial	Infection
LAB 149202F is an acylanilide antimicrobial agent that also has inhibitory effects on strains that produce formyl and phosphate resistance .

Boc-MLF 3 Publications Verification Boc-Met-Leu-Phe-OH	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Boc-MLF is a formyl peptide receptor (FPR) antagonist, and reduces superoxide production induced by fMLF with an IC₅₀ of 0.63 μM .

Boc-FLFLF 1 Publications Verification	Formyl Peptide Receptor (FPR)	Neurological Disease
Boc-FLFLF is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin .

Ac9-25	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .

Anemarrhenasaponin Ia	Reactive Oxygen Species	Inflammation/Immunology
Anemarrhenasaponin Ia, isolated from Anemarrhenae rhizome, inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Anemarrhenasaponin Ia is an useful anti-inflammation reagent .

Ac9-25 TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Ac9-25 TFA, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .

Cat. No.	Product Name	Type

HY-W078435

*1-Ethyl-4-formyl-1h-pyrrole-2-carbonitrile*	Biochemical Assay Reagents
1-Ethyl-4-formyl-1h-pyrrole-2-carbonitrile is a biochemical reagent .

HY-77049

1-Trityl-1H-imidazole-4-carbaldehyde 4-formyl-1-tritylimidazole	Biochemical Assay Reagents
1-Trityl-1H-imidazole-4-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-32813

2-Amino-3-iodopyridine 3-Iodopyridin-2-amine	Biochemical Assay Reagents
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .

Cat. No.	Product Name	Target	Research Area

HY-P0224

*N-Formyl-Met-Leu-Phe* Maximum Cited Publications 9 Publications Verification fMLP; N-formyl-MLF	TNF Receptor	Inflammation/Immunology
N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

HY-P10738

*N-Formyl-MMYALF*	Formyl Peptide Receptor (FPR)	Infection
N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF can inhibit the FPR-1-mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides .

HY-P1744

*N-Formyl-Met-Leu-Phe-Lys* fMLFK	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC₅₀s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D281 ^7.32G, respectively .

HY-P1591

*N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys* For-Nle-Leu-Phe-Nle-Tyr-Lys-OH	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .

HY-P1756

*N-Formyl-Met-Ala-Ser*	Peptides	Inflammation/Immunology
N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.

HY-I0591

*N-Formyl-L-leucine* N-formyl-S-leucine; N-formylleucine; NSC 334321	Amino Acid Derivatives	Others
N-Formyl-L-leucine is a leucine derivative .

HY-W142169

*N-Formyl-L-histidine* formyl-L-histidine	Peptides	Others
N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a K_i value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a K_i value of 4.26 mM .

HY-P10738A

*N-Formyl-MMYALF TFA*	Formyl Peptide Receptor (FPR)	Infection
N-Formyl-MMYALF TFA is a mitochondrial N-formyl peptide that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF TFA can inhibit the FPR-1-mediated chemotactic response of PMNs to bacterial peptides .

HY-P1591A

*N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA* For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .

HY-W141975

*Nε-Formyl-L-lysine*	Amino Acid Derivatives	Others
Nε-Formyl-L-lysine is a lysine derivative .

HY-P2355A

{Boc}-Phe-Leu-Phe-Leu-Phe TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
{Boc}-Phe-Leu-Phe-Leu-Phe TFA is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor .

HY-P2355

{Boc}-Phe-Leu-Phe-Leu-Phe	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor .

HY-W009215

H-Met-Ala-Ser-OH L-Met-L-Ala-L-Ser	Peptides	Others
H-Met-Ala-Ser-OH (L-Met-L-Ala-L-Ser) is a tripeptide. H-Met-Ala-Ser-OH can act as a formyl receptor .

HY-135108

QWF Peptide	Neurokinin Receptor	Neurological Disease
QWF Peptide (Compound 4a) is a substance P antagonist with an IC₅₀ of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC₅₀ of 4.7 μM .

HY-P1117

MMK1	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 is a potent and selective *human formyl* peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing** agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity .

HY-P1117A

MMK1 TFA	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 TFA is a potent and selective *human formyl* peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing** agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity .

HY-103473

Boc-MLF 3 Publications Verification Boc-Met-Leu-Phe-OH	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Boc-MLF is a formyl peptide receptor (FPR) antagonist, and reduces superoxide production induced by fMLF with an IC₅₀ of 0.63 μM .

HY-P1795

Boc-FLFLF 1 Publications Verification	Formyl Peptide Receptor (FPR)	Neurological Disease
Boc-FLFLF is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin .

HY-P1118

Ac9-25	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .

HY-P1118A

Ac9-25 TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Ac9-25 TFA, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR .

HY-P1121A

WKYMVM-NH2 TFA	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase .

HY-P1119

WRW4 4 Publications Verification	Formyl Peptide Receptor (FPR)	Neurological Disease
WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC₅₀ of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide .

HY-P1116

PBP10	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-P1119A

WRW4 TFA	Formyl Peptide Receptor (FPR)	Neurological Disease
WRW4 TFA, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC₅₀ of 0.23 μM. WRW4 TFA specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide .

HY-P5469

WRW4-OH	Formyl Peptide Receptor (FPR)	Others
WRW4-OH is a biological active peptide. (This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.)

HY-P1122

Cyclosporin H 1 Publications Verification	Formyl Peptide Receptor (FPR)	Infection Inflammation/Immunology
Cyclosporin H is a selective and potent inhibitor of *FPR-1 (formyl* peptide receptor 1). Cyclosporin H, a viral transduction** enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.

HY-P1120

WKYMVm	Formyl Peptide Receptor (FPR) PERK Apoptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
WKYMVm is a selective formylpeptide receptor 2 (FPR2) agonist. WKYMVm has a powerful anti-inflammatory effect that can reduce lung injury and spinal cord injury. WKYMVm ameliorates obesity by regulating lipid metabolism and leptin signaling. WKYMVm is involved in the regulation of immune cells by activating FPRs. WKYMVm can promote the chemotactic migration of immune cells and inhibit the apoptosis of phagocytes. In addition, WKYMVm may play a favorable or unfavorable role in tumors, depending on the type of tumor .

HY-P5740

Cacaoidin	Bacterial	Infection
Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile .

Cat. No.	Product Name	Chemical Structure

HY-Y0051S

5-Hydroxymethylfurfural-13C6
5-Hydroxymethylfurfural- ¹³C₆ (2-Hydroxymethyl-5-furfural- ¹³C₆; 2-Formyl-5-hydroxymethylfuran- ¹³C₆) is a ¹³C labeled 5-Hydroxymethylfurfural (HY-Y0051). 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors.

HY-W285163S

1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8
1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d₈ is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.

HY-151454S

*N-Formyl* palbociclib-d8**
N-Formyl palbociclib-d₈ is the deuterium-labeled N-Formyl palbociclib.

HY-W725077S

Benalaxyl metabolite F4-d9
Benalaxyl metabolite F4-d₉ (Methyl N-(2,6-dimethylphenyl)-N-(formyl)-DL-alaninate-d₉) is deuterium labeled Methyl N-(2,6-dimethylphenyl)-N-formylalaninate .

Cat. No.	Product Name		Classification

HY-152714

*5-Formyl-2’-O-methylcytidine*		Nucleosides and their Analogs
5-Formyl-2’-O-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .

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