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propionic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (4) ADC Linker (11) Apoptosis (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (1) CDK (1) COX (1) E3 Ligase Ligand-Linker Conjugates (2) Endogenous Metabolite (17) Fluorescent Dye (1) Fungal (2) iGluR (3) Influenza Virus (1) Isotope-Labeled Compounds (3) Ligands for Target Protein for PROTAC (1) Parasite (2) PROTAC Linkers (7) Reactive Oxygen Species (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (2) Infection (4) Inflammation/Immunology (5) Metabolic Disease (10) Neurological Disease (3)
Click Chemistry:	ADC Synthesis (4) DBCO (2) Azide (2)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

*Imidazole-5-propionic* acid**	Endogenous Metabolite	Metabolic Disease
Imidazole-5-propionic acid is a histidine metabolite .

Propionyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

*3-(3-Hydroxyphenyl)propionic* acid**	Endogenous Metabolite	Cardiovascular Disease
3-(3-Hydroxyphenyl)propionic acid is a flavonoid metabolite formed by human microflora. 3-(3-Hydroxyphenyl)propionic acid shows vasodilatory activity .

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

*FN-1501-propionic* acid**	CDK Ligands for Target Protein for PROTAC	Cancer
FN-1501-propionic acid is a CDK2/9 ligand for PROTAC. FN-1501-propionic acid and a CRBN ligand have been used to design PROTAC CDK2/9 degrader (HY-130709) .

*β-Carboline-1-propionic* acid**	Parasite	Infection
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

*DPH propionic* acid**	Fluorescent Dye	Others
DPH propionic acid is a fluorescent dye .

*Dinotefuran-NHCO-propionic* acid**	Others	Inflammation/Immunology
Dinotefuran-NHCO-propionic acid (4) is an antigen. Dinotefuran-NHCO-propionic acid can couple BSA and OVA to obtain the immunogen and the coating antigen (hapten-OVA conjugate) .

*7-Methoxy-β-carboline-1-propionic* acid**	Parasite	Infection
7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia .

*Dicamba-propionic* acid**	Biochemical Assay Reagents	Others
Dicamba-propionic acid (DCa3) is a heterologous hapten that can be used to develop high-affinity monoclonal antibodies (mAb) against Dicamba. The Dicamba-propionic acid- developed mAb can be used to determine the residual amount of Dicamba in environmental water samples .

*Biotin-PEG3-propionic* hydrazide**	PROTAC Linkers	Cancer
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

*3-(Methylphosphinico)propionic* acid**	Others	Others
3-(Methylphosphinico)propionic acid serves as a metabolite of the pesticide glufosinate ammonium.

*DBCO-PEG3-propionic* EVCit-PAB**	ADC Linker	Cancer
DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-propionic EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*Aminoethyl-SS-propionic* acid**	ADC Linker	Cancer
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

*3-(Methylthio)propionic* acid** 3-Methylsulfanylpropionic acid	Fungal Endogenous Metabolite	Cancer
3-(Methylthio)propionic acid is an intermediate in the methionine metabolism.

*Thalidomide-NH-PEG3-propionic* acid**	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology .

*3-(3-Methoxyphenyl)propionic* acid**	Endogenous Metabolite	Metabolic Disease
3-(3-Methoxyphenyl)propionic acid is an organic acid, naturally occurring human metabolite and excreted in human urine.

*Azidoethyl-SS-propionic* acid**	ADC Linker	Cancer
Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

*Boc-NH-ethyl-SS-propionic* acid**	ADC Linker	Cancer
Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

*Mal-NH-ethyl-SS-propionic* acid**	ADC Linker	Cancer
Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

*Fmoc-NH-ethyl-SS-propionic* acid**	ADC Linker	Cancer
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

*2-(2'-Hydroxy-4'-methylphenyl)propionic* acid**	Others	Others
2-(2'-Hydroxy-4'-methylphenyl)propionic acid is an active compound .

*Azidoethyl-SS-propionic* NHS ester**	ADC Linker	Cancer
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

*(S,R,S)-AHPC-PEG3-propionic* acid**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology .

*Maleimido-tri(ethylene glycol)-propionic* acid** Mal-PEG3-acid	ADC Linker PROTAC Linkers	Cancer
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation . Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

*Fmoc-NH-ethyl-SS-propionic* NHS ester**	ADC Linker	Cancer
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

*(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic* acid**	Amino Acid Derivatives	Others
(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic acid is an alanine derivative .

*Hydroxy-PEG2-CH2CH2COO-PEG2-propionic* acid**	PROTAC Linkers	Cancer
Hydroxy-PEG2-CH2CH2COO-PEG2-propionic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

*DBCO-PEG4-Propionic-Val-Cit-PAB*	ADC Linker	Cancer
DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Dimethylpropiothetin hydrochloride s,s-Dimethyl-β-propionic acid thetine	Endogenous Metabolite	Others
Dimethylpropiothetin hydrochloride (s,s-Dimethyl-β-propionic acid thetine) is the hydrochloride form of dimethylpropiothetin. Dimethylpropiothetin can be isolated in marine algae, and is a precursor to dimethylsulfide (DMS). Dimethylpropiothetin is involved in osmoregulation in Hymenomonas carterae .

*(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic* acid** (S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid; tert-Butoxycarbonyl-L-3-fluorophenylalanine	Amino Acid Derivatives	Others
(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid is a phenylalanine derivative .

*(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4-difluorophenyl)propionic* acid**	Amino Acid Derivatives	Others
(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4-difluorophenyl)propionic acid is a phenylalanine derivative .

*(S)-2-Amino-3-(4-hydroxyphenyl)propionic* acid tert-butyl ester** L-Tyrosine tert-butyl ester; tert-Butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate; tert-Butyl L-tyrosinate	Amino Acid Derivatives	Others
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative .

2,2-Dibromopropanoic acid	Fungal	Infection
2,2-Dibromopropanoic acid is a dibromo product based on propionic acid. Propionic acid is a short chain fatty acid and acts as chemical intermediate. Propionic acid is also a mold inhibitor and widely used in food preservative .

GYKI 53655 hydrochloride LY300168 hydrochloride	iGluR	Neurological Disease
GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.

Zonampanel YM 872	iGluR	Metabolic Disease
Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor.

Bis-PEG7-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Desaminotyrosine 3-(4-Hydroxyphenyl)propionic acid	Influenza Virus Endogenous Metabolite	Infection
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

Ximoprofen	Others	Inflammation/Immunology
Ximoprofen is a propionic nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory property. Ximoprofen can be used for ankylosing spondylitis research .

Deprodone propionate RD20000	Bacterial	Inflammation/Immunology
Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.

3-Indolepropionic acid 2 Publications Verification Indole-3-propionic acid; 3-IPA	Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease
3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

Hexanoylcarnitine	Others	Inflammation/Immunology
Hexanoylcarnitine exists in human urine and plasma. Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .

Hydrocinnamic acid 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid	Endogenous Metabolite	Others
Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

Naproxen glucuronide (S)-Naproxen-β-D-glucuronide	COX	Inflammation/Immunology
Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .

Cat. No.	Product Name	Type

HY-D1743

*DPH propionic* acid**	Fluorescent Dyes/Probes
DPH propionic acid is a fluorescent dye .

Cat. No.	Product Name	Type

HY-134424

Propionyl coenzyme A lithium	Enzyme Substrates
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

Cat. No.	Product Name	Target	Research Area

HY-79165

*(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4-difluorophenyl)propionic* acid**	Amino Acid Derivatives	Others
(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4-difluorophenyl)propionic acid is a phenylalanine derivative .

HY-34519

*(S)-2-Amino-3-(4-hydroxyphenyl)propionic* acid tert-butyl ester** L-Tyrosine tert-butyl ester; tert-Butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate; tert-Butyl L-tyrosinate	Amino Acid Derivatives	Others
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative .

HY-P2595

SKF 103784	Peptides	Cardiovascular Disease
SKF 103784 is an vasopressin antagonist with activity against vasopressin. SKF 103784 inhibits the physiological response caused by antidiuretic and is therefore used to study biological processes related to water and salt balance. SKF 103784 can also be used to explore pathological mechanisms related to cardiovascular diseases and endocrine dysfunction .

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-W003499

*(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic* acid**	Amino Acid Derivatives	Others
(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic acid is an alanine derivative .

HY-79288

*(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic* acid** (S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid; tert-Butoxycarbonyl-L-3-fluorophenylalanine	Amino Acid Derivatives	Others
(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid is a phenylalanine derivative .

Cat. No.	Product Name	Chemical Structure

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

HY-W105506S

Dimethylpropiothetin hydrochloride-d6
(2-Carboxyethyl)dimethylsulfonium-d₆ chloride is the deuterium labeled (2-Carboxyethyl)dimethylsulfonium chloride[1].

HY-Y1088S2

Hydrocinnamic acid-d9
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-Y1088S3

Hydrocinnamic acid-d5
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2].

HY-144418S

*DL-2-Amino-3-(hydroxy-amino)propionic* acid-15N**
DL-2-Amino-3-(hydroxy-amino)propionic acid- ¹⁵N is a ¹⁵N-labeled DL-2-Amino-3-(hydroxy-amino)propionic acid[1].

HY-151084S

*3-(3-Ethoxy-4-methoxyphenyl)propionic-2,2,3,3-d4*
3-(3-Ethoxy-4-methoxyphenyl)propionic-2,2,3,3-d₄ is the deuterium labeled 3-(3-Ethoxy-4-methoxyphenyl)propionic[1].

HY-Y1088S

Hydrocinnamic acid-2,3-13C2
Hydrocinnamic acid-2,3- ¹³C₂ is the ¹³C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

Cat. No.	Product Name		Classification

HY-136141

*DBCO-PEG3-propionic* EVCit-PAB**		ADC Synthesis DBCO
DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-propionic EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140100

*Azidoethyl-SS-propionic* acid**		ADC Synthesis Azide
Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140102

*Azidoethyl-SS-propionic* NHS ester**		Azide ADC Synthesis
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136103

*DBCO-PEG4-Propionic-Val-Cit-PAB*		DBCO ADC Synthesis
DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W725327

1,2-Dipropionyl-sn-glycero-3-phosphocholine 1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-sn-glycero-3-Phosphocholine; PC(3:0/3:0)		Phospholipids
1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.

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