Search Result

Pathways Recommended:	Immunology/Inflammation

Results for "

pulmonary inflammation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (2) Adrenergic Receptor (2) Akt (2) Antibiotic (2) Apoptosis (7) Autophagy (4) Bacterial (2) Cathepsin (1) CCR (1) COX (4) EGFR (1) Elastase (2) Glutathione Peroxidase (2) Hexokinase (2) Histone Methyltransferase (2) IKK (2) Influenza Virus (2) Interleukin Related (8) JAK (1) Keap1-Nrf2 (2) Lipoxygenase (2) mAChR (1) Mitochondrial Metabolism (2) MMP (1) NF-κB (7) NOD-like Receptor (NLR) (2) Notch (2) P2Y Receptor (1) p38 MAPK (5) Parasite (2) Phosphodiesterase (PDE) (6) Phospholipase (1) PI3K (2) Reactive Oxygen Species (5) Src (2) STAT (1) TGF-beta/Smad (2) TGF-β Receptor (2) Thrombin (1) Thymidylate Synthase (1) TNF Receptor (2)
By Research Areas:	Cancer (15) Cardiovascular Disease (5) Endocrinology (2) Infection (2) Inflammation/Immunology (42) Metabolic Disease (2) Neurological Disease (7)

By Targets:

Adenosine Receptor (2)

Adrenergic Receptor (2)

Akt (2)

Antibiotic (2)

Apoptosis (7)

Autophagy (4)

Bacterial (2)

Cathepsin (1)

CCR (1)

COX (4)

EGFR (1)

Elastase (2)

Glutathione Peroxidase (2)

Hexokinase (2)

Histone Methyltransferase (2)

IKK (2)

Influenza Virus (2)

Interleukin Related (8)

JAK (1)

Keap1-Nrf2 (2)

Lipoxygenase (2)

mAChR (1)

Mitochondrial Metabolism (2)

MMP (1)

NF-κB (7)

NOD-like Receptor (NLR) (2)

Notch (2)

P2Y Receptor (1)

p38 MAPK (5)

Parasite (2)

Phosphodiesterase (PDE) (6)

Phospholipase (1)

PI3K (2)

Reactive Oxygen Species (5)

Src (2)

STAT (1)

TGF-beta/Smad (2)

TGF-β Receptor (2)

Thrombin (1)

Thymidylate Synthase (1)

TNF Receptor (2)

By Research Areas:

Cancer (15)

Cardiovascular Disease (5)

Endocrinology (2)

Infection (2)

Inflammation/Immunology (42)

Metabolic Disease (2)

Neurological Disease (7)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19830

AN3199	Phosphodiesterase (PDE)	Inflammation/Immunology
AN3199 is a PDE4 inhibitor with an IC₅₀ of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD) .

HY-123936

SR12343	NF-κB IKK	Neurological Disease Inflammation/Immunology
SR12343, an IKK/NF-κB inhibitor, is a NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic. SR12343 inhibits TNF-α- and LPS-induced NF-κB activation by blocking the interaction between IKKβ and NEMO, with an IC₅₀ of 37.02 μM for TNF-α-mediated NF-κB activation. SR12343 suppresses LPS-induced acute pulmonary inflammation in mice. SR12343 can be used for research of inflammatory and degenerative diseases .

HY-W005379

DGM	TGF-beta/Smad	Inflammation/Immunology
DGM is an inhibitor of the TGF-β1/Smad signaling pathway with significant antifibrotic effects. DGM inhibits the epithelial-mesenchymal transition (EMT) process in alveolar epithelial cells and slows the progression of pulmonary fibrosis in vivo by reducing lung inflammation, improving lung function, and decreasing extracellular matrix (ECM) remodeling. DGM can be used in research on idiopathic pulmonary fibrosis (IPF) and EMT-related diseases .

HY-10404

Dilmapimod 1 Publications Verification SB-681323; GW 681323	p38 MAPK Autophagy	Inflammation/Immunology Cancer
Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

HY-153192

Nerandomilast BI 1015550	Phosphodiesterase (PDE)	Inflammation/Immunology
Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC₅₀ value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) .

HY-153192A

Nerandomilast dihydrate BI 1015550 dihydrate	Phosphodiesterase (PDE)	Inflammation/Immunology
Nerandomilast (BI 1015550) dihydrate is an orally active inhibitor of PDE4B with an IC₅₀ value of 7.2 nM. Nerandomilast (dihydrate) has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) .

HY-107591B

PF-184	IKK	Inflammation/Immunology
PF-184 is a potent and selective IKK-2 inhibitor (IC₅₀: 37 nM) over rhIKK-1, IKKi, and more than 30 tyrosine and serine/threonine kinases. PF-184 can be used in the research of inflammation, such as asthma and chronic obstructive pulmonary disease .

HY-161815

Anti-inflammatory agent 89	Others	Inflammation/Immunology
Anti-inflammatory agent 89 (5c) inhibits all asthma features. Anti-inflammatory agent 89 exhibits a significative effect on the restoration of pulmonary structure and reduction of lung inflammation through both its corticosteroid and H2S releasing component, which is proming for research of Asthma .

HY-10404A

Dilmapimod tosylate SB-681323 tosylate; GW 681323 tosylate	p38 MAPK Autophagy	Inflammation/Immunology Cancer
Dilmapimod tosylate is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

HY-137992

Aucuparin	TGF-beta/Smad	Inflammation/Immunology
Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (HY-108345)-induced lung fibrosis mouse model. Aucuparin has anti-inflammatory activity and can inhibit the activation of inflammatory factors by TGF-β .

HY-P99550

Tozorakimab MEDI-3506	Interleukin Related	Inflammation/Immunology
Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease .

HY-162929

TP-DEA2	TGF-β Receptor	Inflammation/Immunology
TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production .

HY-B0486

Lonidamine Maximum Cited Publications 8 Publications Verification AF-1890; Diclondazolic Acid; DICA	Hexokinase Mitochondrial Metabolism Apoptosis Parasite	Inflammation/Immunology Cancer
Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (K_i: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis .

HY-132831B

Selnoflast potassium Somalix potassium; RO-7486967 potassium; IZD334 potassium	NOD-like Receptor (NLR) Interleukin Related	Inflammation/Immunology
Selnoflast (RO-7486967) Potassium, formerly Somalix/RG6418/IZD334, Selnoflast is an orally available inhibitor of NLRP3. Selnoflast is used in the study of systemic inflammation, such as ulcerative colitis and chronic obstructive pulmonary disease .

HY-12335

UNC0379 5+ Cited Publications	Histone Methyltransferase	Inflammation/Immunology Cancer
UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC₅₀ of 7.3 μM, K_D value of 18.3 μM. UNC0379 can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer, neuroblastoma .

HY-12335A

UNC0379 TFA	Histone Methyltransferase	Inflammation/Immunology Cancer
UNC0379 TFA is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC₅₀ of 7.3 μM, K_D value of 18.3 μM. UNC0379 TFA can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer, neuroblastoma .

HY-N0232

Psoralidin 4 Publications Verification	COX Lipoxygenase Notch Reactive Oxygen Species Bacterial	Cancer
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-145581

Mitiperstat AZD4831	Glutathione Peroxidase	Cardiovascular Disease
Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease .

HY-103363

SB-328437 1 Publications Verification	CCR Thymidylate Synthase	Inflammation/Immunology Cancer
SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC₅₀ of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases .

HY-132831A

Selnoflast calcium Somalix calcium; RO-7486967 calcium; IZD334 calcium	NOD-like Receptor (NLR) Interleukin Related	Inflammation/Immunology
Selnoflast (RO-7486967) calcium Formerly known as Somalix/RG6418/IZD334, Selnoflast is an orally available inhibitor of NLRP3. Selnoflast is used in the study of systemic inflammation, such as ulcerative colitis and chronic obstructive pulmonary disease[1]/s.br/ .

HY-P99673

Itepekimab REGN-3500; SAR-440340	Interleukin Related NF-κB	Inflammation/Immunology
Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) .

HY-B0486R

Lonidamine (Standard)	Hexokinase Mitochondrial Metabolism Apoptosis Parasite	Inflammation/Immunology Cancer
Lonidamine (Standard) is the analytical standard of Lonidamine. This product is intended for research and analytical applications. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (K_i: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis .

HY-P3293A

Lonodelestat TFA POL6014 TFA	Elastase	Inflammation/Immunology
Lonodelestat TFA (POL6014 TFA) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat TFA has the potential for the research of cystic fibrosis (CF) .

HY-P3293

Lonodelestat POL6014	Elastase	Inflammation/Immunology
Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat (POL6014) has the potential for the research of cystic fibrosis (CF) .

HY-172135

PDE4-IN-26	p38 MAPK Phosphodiesterase (PDE)	Inflammation/Immunology
PDE4-IN-26 (Compound A5) is an orally active and highly selective PDE4 inhibitor. PDE4-IN-26 has anti-inflammatory activity and can inhibit the phosphorylation of p38 MAPK. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 can improve pulmonary inflammation, injury and fibrosis, promote sputum secretion and relieve cough in mice. PDE4-IN-26 can be used for the research of lung injury-related diseases .

HY-B0004

Doxofylline	Adenosine Receptor Phosphodiesterase (PDE) Reactive Oxygen Species	Inflammation/Immunology
Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm .

HY-114374

RO5461111	Cathepsin	Inflammation/Immunology
RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC₅₀s of 0.4 nM (human Cathepsin S) and 0.5 nM (murine Cathepsin S), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus nephritis .

HY-W011733

Tulobuterol hydrochloride 1 Publications Verification C-78	Adrenergic Receptor Influenza Virus Antibiotic	Infection Inflammation/Immunology Endocrinology
Tulobuterol hydrochloride (C-78) is a long-acting β₂-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation .

HY-N0232R

Psoralidin (Standard)	COX Lipoxygenase Notch Reactive Oxygen Species Bacterial	Cancer
Psoralidin (Standard) is the analytical standard of Psoralidin. This product is intended for research and analytical applications. Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-145532

S-Allylmercaptocysteine	Apoptosis NF-κB Keap1-Nrf2	Inflammation/Immunology Cancer
S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation .

HY-W011733R

Tulobuterol (hydrochloride) (Standard)	Adrenergic Receptor Influenza Virus Antibiotic	Infection Inflammation/Immunology Endocrinology
Tulobuterol (hydrochloride) (Standard) is the analytical standard of Tulobuterol (hydrochloride). This product is intended for research and analytical applications. Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation .

HY-B0004R

Doxofylline (Standard)	Adenosine Receptor Phosphodiesterase (PDE) Reactive Oxygen Species	Inflammation/Immunology
Doxofylline (Standard) is the analytical standard of Doxofylline. This product is intended for research and analytical applications. Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm .

HY-N8278

Dermatan sulphate sodium	Thrombin	Cardiovascular Disease Inflammation/Immunology
Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation .

HY-N0512

Loganin 4 Publications Verification Loganoside	Reactive Oxygen Species TNF Receptor Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .

HY-19638A

Cangrelor tetrasodium 2 Publications Verification AR-C69931MX tetrasodium	P2Y Receptor	Cardiovascular Disease Inflammation/Immunology
Cangrelor tetrasodium, an adenosine triphosphate analogue, is a reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects. Cangrelor tetrasodium directly blocks adenosine diphosphate (ADP)-induced activation and aggregation of platelets. Cangrelor tetrasodium is also a nonspecific GPR17 antagonist .

HY-N0031R

Plantamajoside (Standard)	NF-κB PI3K Apoptosis Autophagy p38 MAPK Src	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Plantamajoside (Standard) is the analytical standard of Plantamajoside. This product is intended for use in research and analytical applications. Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates MAPK, integrin-linked kinase/c-Src. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects .

HY-N0031

Plantamajoside 1 Publications Verification	NF-κB PI3K Akt Apoptosis Autophagy p38 MAPK Src	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates MAPK, integrin-linked kinase/c-Src. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects .

HY-N2429

Sphondin	COX	Inflammation/Immunology
Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE₂ release in A549 cells .

HY-147742

Thi-DPPY	JAK	Inflammation/Immunology
Thi-DPPY (compound 8e) is a potent and orally active JAK3 inhibitor with IC₅₀ values of 62.4, 1.38 nM for BTK, JAK, respectively. Thi-DPPY shows anti-proliferative activity against HBE cells. Thi-DPPY shows anti-inflammatory activity in vivo. Thi-DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF) .

HY-123461

Sul-121 hydrochloride	NF-κB	Inflammation/Immunology
Sul-121 hydrochloride is a novel compound with anti-oxidative capacity that effectively inhibits airway inflammation and hyperresponsiveness (AHR) in experimental models of chronic obstructive pulmonary disease (COPD). Sul-121 hydrochloride prevents lipopolysaccharide-induced airway neutrophilia and AHR in a dose-dependent manner. Sul-121 hydrochloride also demonstrates the ability to reduce oxidative stress markers in human airway smooth muscle cells. Sul-121 hydrochloride inhibits nuclear translocation of the NF-κB subunit, p65, thereby diminishing pro-inflammatory cytokine release.

HY-N0512R

Loganin (Standard)	Apoptosis Keap1-Nrf2 TNF Receptor Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
Loganin (Standard) is the analytical standard of Loganin. This product is intended for research and analytical applications. Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) .

HY-127110

AK106-001616	Phospholipase	Others Neurological Disease Inflammation/Immunology
AK106-001616 is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2) (IC₅₀=3.8 nmol/L). AK106-001616 is able to reduce the production of prostaglandins (PG) E2 and leukotrienes (LT) B4 by stimulated cells. AK106-001616 can be used in the study of inflammatory diseases, neuropathic pain and pulmonary fibrosis .

HY-100958

4-DAMP 3 Publications Verification 4-DAMP methiodide	mAChR Apoptosis MMP EGFR Interleukin Related	Inflammation/Immunology Cancer
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .

HY-103388

NCX 466	COX TGF-β Receptor Glutathione Peroxidase	Inflammation/Immunology
NCX 466 is an orally active COX-1 and COX-2 inhibitor that exhibits anti-inflammatory and analgesic effects. Additionally, NCX 466 acts as a NO donor, exerting anti-inflammatory and antioxidant effects by improving microcirculation. NCX 466 significantly reduces the levels of transforming growth factor-β (TGF-β) and oxidative stress markers (such as thiobarbituric acid reactive substances (TBARS) and 8-hydroxy-2'-deoxyguanosine (8-OHdG)), and it decreases leukocyte recruitment during inflammation by reducing myeloperoxidase (MPO) activity, thereby preventing bleomycin (HY-108345)-induced pulmonary fibrosis in mice .

HY-P10854

TAT-N15	NF-κB Interleukin Related STAT Akt	Neurological Disease Inflammation/Immunology
TAT-N15 is a p55PIK inhibitor with remarkable anti-inflammatory activity and neuroprotective effects. TAT-N15 can significantly inhibit the activation of IL-6, IL-8, Akt, and NF-κB pathways, as well as suppress the protein expression of phosphorylated STAT3 and NF-κB. By inhibiting the activation of Akt, STAT3, and NF-κB pathways, TAT-N15 is used in research on acute conjunctivitis, allergic rhinitis, chronic obstructive pulmonary disease (COPD), and stroke .

Cat. No.	Product Name

HY-L114

Anti-inflammatory Traditional Chinese Medicine Active Compound Library

1,181 compounds

Inflammation promotes physiological and pathological processes by the activation of the immune system, local vascular system, and various cells within the damaged tissue. Accumulating epidemiological and clinical evidence shows that chronic inflammation is causally linked to various human diseases, including cerebrovascular, cardiovascular, joint, cutaneous, pulmonary, blood, liver, and intestinal diseases as well as diabetes.

Various natural products from Traditional Chinese Medicine (TCM) have been shown to safely suppress proinflammatory pathways and control inflammation-associated disease. MCE designs a unique collection of 1,181 Traditional Chinese Medicine active compounds with anti-inflammatory activity, which are derived from Coptis chinensis, Radix isatidis, Flos Lonicerae, Forsythia suspensa, etc. MCE Anti-inflammatory Traditional Chinese Medicine Active Compound Library is a useful tool for discovery anti-inflammatory drugs from TCM.

Cat. No.	Product Name	Target	Research Area