Search Result
Results for "
spectrometry
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P3363
-
|
Caspase
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Cancer
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Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
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-
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- HY-W041994
-
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Biochemical Assay Reagents
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Cancer
|
GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins .
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-
-
- HY-A0135
-
|
Potassium Channel
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Neurological Disease
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Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca 2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry .
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- HY-107641
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α-Cyano-4-hydroxycinnamate
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Monocarboxylate Transporter
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Metabolic Disease
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α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .
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- HY-113005
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Endogenous Metabolite
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Metabolic Disease
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Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
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- HY-113005A
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|
Endogenous Metabolite
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Metabolic Disease
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Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes .
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- HY-113005S
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|
Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Glutarylcarnitine-d9 (chloride) is the deuterium labeled Glutarylcarnitine chloride. Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
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- HY-45609
-
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iGluR
Endogenous Metabolite
|
Neurological Disease
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L-Cysteine S-sulfate sodium hydrate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry operations .
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- HY-157414
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Others
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Others
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Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS) .
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- HY-W105853
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Trifluoroacetic acid amine
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Biochemical Assay Reagents
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Others
|
Ammonium trifluoroacetate is an additive for regulating and calibrating new liquid/mass spectrometry systems .
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- HY-131389
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Others
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Others
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Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
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- HY-155789
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Ceramide trihexoside (d18:1/17:0); Gb3(d18:1)(C17:0)
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Others
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Others
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C17 Globotriaosylceramide (d18:1/17:0) is a sphygosine lipid that can be used to quantify Globotriaosylceramide in plasma and urine of patients with Fabry disease by gas chromatography-mass spectrometry (GC-MS) .
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- HY-165127
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(+)-Octopinic acid
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Others
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Others
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Octopinic acid ((+)-Octopinic acid) is a biomarker (opine) for plant crown gall or hairy root disease detected by ultra-performance liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry with activity useful for disease diagnosis and analysis.
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- HY-113084
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iGluR
Endogenous Metabolite
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Neurological Disease
|
L-Cysteine S-sulfate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptor agonist. L-Cysteine S-sulfate is the substrate for cystine lyase, and can be used in mass spectrometry operations .
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- HY-100787
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iGluR
Endogenous Metabolite
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Neurological Disease
|
L-Cysteine S-sulfate sodium is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry operations .
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- HY-165109
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1,3-Olein-2-laurin; TG(18:1/12:0/18:1)
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Others
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Others
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1,3-Dioleoyl-2-lauroyl glycerol (1,3-Olein-2-laurin), a compound in the triglyceride composition of human milk, was identified and quantified by liquid chromatography-mass spectrometry, and a targeted analytical approach was developed.
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-
- HY-44157
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Biochemical Assay Reagents
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Neurological Disease
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ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain .
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- HY-165049
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1-Stearin-2-olein-3-linolein; TG(18:0/18:1/18:2)
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Others
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Others
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1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol (1-Stearin-2-olein-3-linolein), a compound in the triglyceride composition of ostrich oil, was analyzed and identified by specific chromatography-mass spectrometry techniques.
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- HY-135543
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Endogenous Metabolite
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Neurological Disease
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Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
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- HY-127151
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Levophencynonate hydrochloride
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Others
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Neurological Disease
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Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity .
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- HY-123740
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DSSO
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Biochemical Assay Reagents
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Others
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Disuccinimidyl sulfoxide (DSSO) is a mass spectrometry (MS)-cleavable cross-linker that is applicable for model peptides and proteins and a multisubunit protein complex. Disuccinimidyl sulfoxide contains two symmetric collision-induced dissociation (CID)-cleavable sites for identification of DSSO-cross-linked peptides based their distinct fragmentation patterns .
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- HY-165056
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1,2-Palmitin-3-linolein; TG(16:0/16:0/18:2)
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Others
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Others
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1,2-Dipalmitoyl-3-linoleoyl-rac-glycerol (1,2-Palmitin-3-linolein), a compound mentioned in the chemical analysis of triglycerides and diacylglycerols in bovine milk fat, was identified by a specific chromatography-mass spectrometry technique, which is environmentally friendly and efficient.
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- HY-165042
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1,2-Palmitin-3-caprin; 1,2-Palmitin-3-decanoin; TG(16:0/16:0/10:0)
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Others
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Others
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1,2-Dipalmitoyl-3-decanoyl-rac-glycerol (1,2-Palmitin-3-caprin), a compound mentioned in the chemical analysis of triglycerides and diacylglycerols in bovine milk fat, was identified by a specific chromatography-mass spectrometry technique, which is environmentally friendly and efficient.
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- HY-165051
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1,3-Butyrin-2-olein; TG(4:0/18:1/4:0)
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Others
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Others
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1,3-Dibutyryl-2-oleoyl glycerol (1,3-Butyrin-2-olein) is a short-chain triglyceride compound in bovine milk fat. It was analyzed by specific chromatography-mass spectrometry techniques to determine its distribution and composition in bovine milk fat.
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- HY-165050
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18:2/18:0/18:2-TG; TG(18:2/18:0/18:2)
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Others
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Others
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1,3-Dilinoleoyl-2-stearoyl glycerol (18:2/18:0/18:2-TG) is a compound used in the study of triglyceride composition of vegetable oils. It was analyzed by supercritical CO? chromatography-mass spectrometry to determine its content and characteristics in different vegetable oils.
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-
- HY-W713076
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-
-
- HY-165108
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1,2-Linolein-3-α-linolenin; TG(18:2/18:2/18:3)
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Others
|
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1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol (1,2-Linolein-3-α-linolenin) is a compound used in the study of triglyceride composition of vegetable oils. It was analyzed by supercritical CO? chromatography-mass spectrometry to determine its content and characteristics in different vegetable oils.
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- HY-158725
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Others
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Others
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N-Octadecenoyl-(cis-9) -Sulfatide is a glycolipid found in the brains of mice. N-Octadecenoyl-(cis-9) -Sulfatide can be used as a standard for the determination of C18:13 '-mergogalactosyllactose in dry blood stains of patients with chromatic leukodystrophy (MLD) by ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) .
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- HY-165055
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1-Olein-2-palmitin-3-linolein; TG(18:1/16:0/18:2); 18:1/16:0/18:2-TG
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Others
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Others
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1-Oleoyl-2-palmitoyl-3-linoleoyl-rac-glycerol (1-Olein-2-palmitin-3-linolein) is a compound mentioned in the chemical analysis of triglycerides and diacylglycerols in bovine milk fat. It was identified by a specific chromatography-mass spectrometry technique, which is environmentally friendly and efficient.
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-
-
- HY-165116
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18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)
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Others
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Others
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1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.
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-
- HY-165054
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1-Palmitin-2-stearin-3-olein; TG(16:0/18:0/18:1)
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Others
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Others
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1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol (1-Palmitin-2-stearin-3-olein), a compound used in the study of changes in diglyceride and triglyceride molecular species in cells, was analyzed by neutral loss mass spectrometry and its content was found to change after cell activation.
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-
- HY-165105
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TG(18:1/10:0/18:1); 1,3-Dioleoyl-2-caproyl glycerol; 1,3-Olein-2-caprin
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Others
|
Others
|
1,3-Dioleoyl-2-decanoyl glycerol (TG(18:1/10:0/18:1)) is a compound that was investigated in the study of triglyceride composition in human milk and infant formula. The analysis and comparison of the compound using a specific chromatography-mass spectrometry technique revealed differences in triglyceride content between human milk and infant formula.
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- HY-165095
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1,2-Palmitolein-3-palmitin; TG(16:1/16:1/16:0)
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Others
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Others
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1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol (1,2-Palmitolein-3-palmitin) is a triglyceride used for serum lipidomics analysis by liquid chromatography-mass spectrometry. This method can effectively separate and detect lipids in positive and negative ionization modes and has certain performance in the identification and characterization of serum triglycerides.
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- HY-116870
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|
Parasite
|
Infection
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Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
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-
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- HY-165091
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1,2-Octanoin-3-decanoin; TG(8:0/8:0/10:0)
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Others
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Others
|
1,2-Dioctanoyl-3-decanoyl-rac-glycerol (1,2-Octanoin-3-decanoin) is a triglyceride identified in microalgae biomass by ion mobility-mass spectrometry. It can be used to characterize microalgae biomass. Different analytical strategies can determine its distribution in different microalgae and its relationship with other compounds, which has application value in biofuel production.
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- HY-147064A
-
|
Endogenous Metabolite
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Others
|
DL-4-Hydroxy-2-ketoglutarate serves as a substrate for the enzymes GOT (glutamic oxalacetic aminotransferase) and 2-keto-4-hydroxyglutarate aldolase, facilitating the reversible breakdown of 2-keto-4-hydroxyglutarate into pyruvate and glyoxylate; it has also found applications in mass spectrometry for the swift analysis of negatively charged, water-soluble cellular metabolites.
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-
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- HY-W011336
-
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Phosphodiesterase (PDE)
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Others
|
PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1 .
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-
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- HY-N12143
-
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Others
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Others
|
Acetylthevetin A is a natural product isolated from oleander (Cascabela thevetioides) .
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-
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- HY-117637
-
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Others
|
Neurological Disease
|
ALS-I-41 is a novel, potent and selective oxytocin receptor antagonist with the potential to modulate biological activities related to social behavior and mental disorders. ALS-I-41 is being evaluated for behavioral pharmacology experiments in non-human primates and can be administered via intranasal or intramuscular injection. The central nervous system penetration and metabolic rate of ALS-I-41 were studied by mass spectrometry analysis in cerebrospinal fluid and plasma of macaque monkeys .
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- HY-118730
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Andalin; DU 319722; A 1335
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Others
|
Infection
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Flucycloxuron (Andalin) is an insect growth regulator (IGR) .
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-
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- HY-118730R
-
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Others
|
Infection
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Flucycloxuron (Standard) is the analytical standard of Flucycloxuron. This product is intended for research and analytical applications. Flucycloxuron (Andalin) is an insect growth regulator (IGR) .
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- HY-123023
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Others
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Cancer
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12(S)-HETE D8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE D8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE D8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.
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- HY-132246
-
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MAGL
|
Neurological Disease
|
WWL123 analogue-1 is an analogue of WWL123. WWL123 is a potent and selective ABHD6 inhibitor with an IC50 of 430 nM . WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice .
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-
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- HY-N8639
-
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Others
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Others
|
Chrysin 8-C-β-D-glucoside is a natural compound isolated from the herbs of Psidium guajava .
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-
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- HY-135152
-
|
Reactive Oxygen Species
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Cancer
|
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .
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-
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- HY-D1546
-
|
Fluorescent Dye
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Cancer
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
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-
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- HY-N1156
-
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Others
|
Others
|
Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana .
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-
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- HY-126720
-
|
Endogenous Metabolite
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Metabolic Disease
|
N-Lignoceroyl Taurine is an arachidonoyl amino acid and taurine conjugate with a fatty acid that can be isolated from bovine brain. N-Lignoceroyl Taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of the brain and spinal cord of wild-type and fatty acid amide hydrolase (FAAH) knockout mice. N-Lignoceroyl Taurine levels were 23-26-fold higher in FAAH -/- mice compared to wild-type mice, suggesting that FAAH utilizes N-Lignoceroyl Taurine as a substrate. However, in vitro experiments with purified FAAH showed that N-Lignoceroyl Taurine was hydrolyzed 2,000-fold slower in FAAH compared to oleoylethanolamide. N-Acyl Taurines with polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) calcium channel family, including TRPV1 and TRPV4.
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- HY-136490
-
Galactosylsphingosine
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PKC
|
Neurological Disease
Cancer
|
Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease . Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis. Psychosine also is an inhibitor of PKC .
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-
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- HY-W010736A
-
|
Biochemical Assay Reagents
|
Others
|
1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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-
- HY-N7844
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Benzyladenosine
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Apoptosis
Adenosine Receptor
|
Inflammation/Immunology
Cancer
|
N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma - .
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-
Cat. No. |
Product Name |
Type |
-
- HY-P3363
-
|
Chromogenic Substrates
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
-
- HY-D1546
-
|
Fluorescent Dyes/Probes
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
Cat. No. |
Product Name |
Type |
-
- HY-W105853
-
Trifluoroacetic acid amine
|
Buffer Reagents
|
Ammonium trifluoroacetate is an additive for regulating and calibrating new liquid/mass spectrometry systems .
|
-
- HY-167817
-
18:1 Phosphatidylpropanol sodium
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Cell Assay Reagents
|
1,2-Dioleoyl-sn-glycero-3-phosphopropanol sodium (18:1 Phosphatidylpropanol sodium) is a bioactive phospholipid that has the capability to be used in mass spectrometry analysis and is able to effectively quantify Peth in human blood.
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-
- HY-147064A
-
|
Biochemical Assay Reagents
|
DL-4-Hydroxy-2-ketoglutarate serves as a substrate for the enzymes GOT (glutamic oxalacetic aminotransferase) and 2-keto-4-hydroxyglutarate aldolase, facilitating the reversible breakdown of 2-keto-4-hydroxyglutarate into pyruvate and glyoxylate; it has also found applications in mass spectrometry for the swift analysis of negatively charged, water-soluble cellular metabolites.
|
-
- HY-W010736A
-
|
Biochemical Assay Reagents
|
1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P3363
-
|
Caspase
|
Cancer
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
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- HY-P5531
-
|
Peptides
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Others
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beta-Casein phosphopeptide is a biological active peptide. (Bovine ?-Casein, monophosphopeptide (phospho-Serine) can be used for characterization of affinity purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry.)
|
-
- HY-113084
-
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
L-Cysteine S-sulfate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptor agonist. L-Cysteine S-sulfate is the substrate for cystine lyase, and can be used in mass spectrometry operations .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113005S
-
|
Glutarylcarnitine-d9 (chloride) is the deuterium labeled Glutarylcarnitine chloride. Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
|
-
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