Biotin-C2-maleimide

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Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule.

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Biotin-C2-maleimide Chemical Structure

CAS No. : 139554-72-6

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5 mg	USD 84	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	USD 126	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	USD 245	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	USD 368	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	USD 553	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description	Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule^[1]^[2].
In Vitro	Biotin-C2-maleimide can act bioconjugation with 5 eq. SUMO-1 probes^[1]. 1. Biotin C2 maleimide (ATT Bioquest, dissolved in DMSO) is performed in Tris buffer (50 mM Tris, 300 mM NaCl; pH 7.0) after 15 min reduction with Tris (2-carboxyethyl)phosphine (TCEP, 120 μM) at room temperature. 2. After 1 h incubation, the unreacted Biotin is separated by Ni-NTA affinity chromatography followed by dialysis against PBS buffer (pH 7.4). MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Biotin-C2-maleimide Related Antibodies
Molecular Weight	366.44
Formula	C₁₆H₂₂N₄O₄S
CAS No.	139554-72-6
SMILES	O=C(NCCN1C(C=CC1=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Benjamin GD, et al. Antibody conjugates and methods of making the antibody conjugates: United States, US20160361436A1. 2016-12-15. [2]. Brüninghoff K, Wulff S, Dörner W, Geiss-Friedlander R, Mootz HD. A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders. Front Chem. 2022 May 30;10:900989. [Content Brief]