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sulfides

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58

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3

Fluorescent Dye

4

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11

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5

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013186S
    Lansoprazole sulfide-d4

    AG-1777-d4

    		 Proton Pump Bacterial Inflammation/Immunology
    Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
    Lansoprazole sulfide-d4
  • HY-W103170
    1,8-Dichloroanthraquinone

    		Bacterial Others
    1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .
    1,8-Dichloroanthraquinone
  • HY-W196803
    Dipropyl disulfide

    Propyl Disulfide; DPDS

    		 Cytochrome P450 Others
    Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .
    Dipropyl disulfide
  • HY-D1275
    CAY10731

    		Fluorescent Dye Others
    CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
    CAY10731
  • HY-119323
    7-Azido-4-methylcoumarin

    		Fluorescent Dye Others
    7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    7-Azido-4-methylcoumarin
  • HY-141776S
    Omeprazole sulfide-d3

    Ufiprazole-d3

    		 Drug Metabolite Others
    Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
    Omeprazole sulfide-d3
  • HY-126124
    AP39
    5 Publications Verification

    		 Reactive Oxygen Species Cardiovascular Disease Neurological Disease
    AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
    AP39
  • HY-B1786S
    Sulindac sulfide-d3

    cis-Sulindac sulfide-d3

    		 γ-secretase Neurological Disease
    Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide-d3
  • HY-G0006R
    Omeprazole sulfide (Standard)

    		Drug Metabolite Others
    Omeprazole sulfide (Standard) is the analytical standard of Omeprazole sulfide. This product is intended for research and analytical applications. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole.
    Omeprazole sulfide (Standard)
  • HY-W013186S1
    Lansoprazole sulfide-13C6

    AG-1777-13C6

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Lansoprazole sulfide- 13C6 is a deuterated labeled Lansoprazole sulfide .
    Lansoprazole sulfide-13C6
  • HY-B1786R
    Sulindac sulfide (Standard)

    		Drug Metabolite γ-secretase Neurological Disease
    Sulindac sulfide (Standard) is the analytical standard of Sulindac sulfide. This product is intended for research and analytical applications. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide (Standard)
  • HY-128447
    Allyl methyl sulfide

    		Bacterial Endogenous Metabolite Infection Cancer
    Allyl methyl sulfide is a bioactive organosulfur compound found in garlic. Allyl methyl sulfide exhibits antibacterial, antioxidant and anticancer properties .
    Allyl methyl sulfide
  • HY-W250123R
    Dibutyl sulfide (Standard)

    		Biochemical Assay Reagents Others
    Dibutyl sulfide (Standard) is the analytical standard of Dibutyl sulfide. This product is intended for research and analytical applications. Dibutyl sulfide is an oily liquid commonly used as a solvent, extractant and flavoring agent in various industrial processes, especially in the production of petroleum products, polymers and food additives. Dibutyl sulfide has unique chemical properties that make it an active ingredient in many applications requiring high solvency and low volatility.
    Dibutyl sulfide (Standard)
  • HY-B1786A
    (E/Z)-Sulindac sulfide

    		γ-secretase Amyloid-β Neurological Disease
    (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer’s disease .
    (E/Z)-Sulindac sulfide
  • HY-W013186
    Lansoprazole sulfide

    AG-1777

    		 Drug Metabolite Bacterial Inflammation/Immunology Cancer
    Lansoprazole sulfide is an active metabolite of Lansoprazole by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC50 of 0.59 µM for M. tb .
    Lansoprazole sulfide
  • HY-W003467R
    Rabeprazole Sulfide (Standard)

    		Proton Pump Bacterial Infection Inflammation/Immunology
    Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide. This product is intended for research and analytical applications. Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
    Rabeprazole Sulfide (Standard)
  • HY-G0006
    Omeprazole sulfide

    Ufiprazole

    		 Drug Metabolite Others
    Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole.
    Omeprazole sulfide
  • HY-144439
    HTS07545

    		Mitochondrial Metabolism Cardiovascular Disease
    HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .
    HTS07545
  • HY-N12977
    Dipropenyl sulfide

    		Others Others
    Dipropenyl sulfide is a constituent of Garlic oil, onion oil .
    Dipropenyl sulfide
  • HY-W250123
    Dibutyl sulfide

    		Biochemical Assay Reagents Others
    Dibutyl sulfide is an oily liquid commonly used as a solvent, extractant and flavoring agent in various industrial processes, especially in the production of petroleum products, polymers and food additives. Dibutyl sulfide has unique chemical properties that make it an active ingredient in many applications requiring high solvency and low volatility.
    Dibutyl sulfide
  • HY-W016033
    Pantoprazole sulfide

    		Drug Metabolite Proton Pump Metabolic Disease
    Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor .
    Pantoprazole sulfide
  • HY-123615
    SPD-2

    		Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    SPD-2 is a photo-controlled hydrogen sulfide (H2S) donor that can generate hydrogen sulfide (H2S) upon UVA irradiation (325-385 nm). SPD-2 enables photo-controlled, site-specific H2S release in living cells .
    SPD-2
  • HY-P2995
    Hemoglobin

    		Biochemical Assay Reagents Heme Oxygenase (HO) Others
    Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant .
    Hemoglobin
  • HY-138187
    4-Hydroxy omeprazole sulfide

    		Proton Pump Metabolic Disease
    4-Hydroxy omeprazole sulfide is a metabolite of the proton pump inhibitor Omeprazole (HY-B0113) .
    4-Hydroxy omeprazole sulfide
  • HY-W143071S
    1-(Methylthio)-pentane-d3

    		Isotope-Labeled Compounds Others
    1-(Methylthio)-pentane-d3 is the deuterium labeled Amyl methyl sulfide (HY-W143071) .
    1-(Methylthio)-pentane-d3
  • HY-W110707
    Cetylamine

    Hexadecylamine

    		 Biochemical Assay Reagents Cancer
    Cetylamine (Hexadecylamine) denatures proteins faster and prevents flocculation. Cetylamine can cap zinc sulfide nanoparticles and is used in cancer research .
    Cetylamine
  • HY-B1786
    Sulindac sulfide
    1 Publications Verification

    cis-Sulindac sulfide

    		 Drug Metabolite γ-secretase Neurological Disease
    Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
    Sulindac sulfide
  • HY-E70078
    Cystathionine β-synthase

    		Biochemical Assay Reagents Others
    Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
    Cystathionine β-synthase
  • HY-160240
    HPI

    		Fluorescent Dye Others Cancer
    HPI is a HS - fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS - form of hydrogen sulfide (H2S) gas in environmental water samples .
    HPI
  • HY-109582
    ADT-OH
    2 Publications Verification

    5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1

    		 Apoptosis FAK Cancer
    ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH
  • HY-W003467
    Rabeprazole Sulfide

    		Proton Pump Bacterial Infection Inflammation/Immunology
    Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
    Rabeprazole Sulfide
  • HY-100287
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

    		Prostaglandin Receptor Phospholipase Endocrinology
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
  • HY-141552
    FC9402
    1 Publications Verification

    		 Mitochondrial Metabolism Cardiovascular Disease
    FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .
    FC9402
  • HY-120425
    Ethiprole

    		Insecticide Infection
    Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
    Ethiprole
  • HY-121955
    FW1256
    1 Publications Verification

    		 NF-κB Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment .
    FW1256
  • HY-20794
    8-Hydroxyjulolidine

    		Fluorescent Dye Others
    8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .
    8-Hydroxyjulolidine
  • HY-P10486
    AIP-II

    		Bacterial Infection
    AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor .
    AIP-II
  • HY-D1256
    Msr-blue

    		Fluorescent Dye Neurological Disease Metabolic Disease
    Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .
    Msr-blue
  • HY-120425R
    Ethiprole (Standard)

    		Insecticide Infection
    Ethiprole (Standard) is the analytical standard of Ethiprole. This product is intended for research and analytical applications. Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
    Ethiprole (Standard)
  • HY-129303
    AP219

    		Endogenous Metabolite Metabolic Disease
    AP39 (Item No. 17100) is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion.
    AP219
  • HY-134495
    N-Acetyl-L-cysteine ethyl ester
    5+ Cited Publications

    N-Acetylcysteine ethyl ester; NACET

    		 Reactive Oxygen Species Metabolic Disease
    N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
    N-Acetyl-L-cysteine ethyl ester
  • HY-D2476
    H2S Fluorescent probe 1

    		Fluorescent Dye Others
    H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
    H2S Fluorescent probe 1
  • HY-P2331
    Actagardin

    Antibiotic A 3802-IV-3; Gardimycin

    		 Antibiotic Infection
    Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
    Actagardin
  • HY-112555
    PDE7-IN-2

    		Phosphodiesterase (PDE) Neurological Disease
    PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease .
    PDE7-IN-2
  • HY-P2031
    Phallacidin

    		Arp2/3 Complex Others
    Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
    Phallacidin
  • HY-B0380B
    Trimebutine (3-TCBS)

    GIC-1001

    		 Biochemical Assay Reagents Others
    Trimebutine 3-TCBS (GIC-1001) is an innovative formulation designed to release hydrogen sulfide (H2S) in vivo. This compound combines trimebutine with an H2S-releasing antagonist (phenyl 3-thiocarbamate) and exhibits enhanced anti-nociceptive effects in a mouse colonic distension model, superior to conventional trimebutine. GIC-1001 can reduce visceral pain and discomfort associated with lumen distension in a dose-dependent manner, showing potential superiority .
    Trimebutine (3-TCBS)
  • HY-106784A
    (E)-Ajoene

    		Fungal Apoptosis Neurological Disease
    (E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
    (E)-Ajoene
  • HY-P0028
    Phalloidin
    Maximum Cited Publications
    14 Publications Verification

    		 Fluorescent Dye Others
    Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .
    Phalloidin
  • HY-P1695
    Cinnamycin

    Ro 09-0198

    		 Antibiotic Bacterial Infection
    Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .
    Cinnamycin
  • HY-P3143
    BMSpep-57

    		PD-1/PD-L1 Cancer
    BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50?of 7.68?nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST?and SPR assays, respectively.?BMSpep-57?facilitates T cell function by in creasing IL-2 production in PBMCs .
    BMSpep-57

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