1. Search Result
Search Result
Results for "

tissue specificity

" in MedChemExpress (MCE) Product Catalog:

67

Inhibitors & Agonists

3

Screening Libraries

30

Biochemical Assay Reagents

10

Peptides

3

Natural
Products

1

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122331

    Calcium Channel Cardiovascular Disease
    Norbormide shows vasoconstrictor activity by blocking calcium channel. The activity of Norbormide is species- and tissue-specific, endothelium independent, and is restricted to the peripheral arteries of rat. Norbormide is also a toxicant, and the oral LD50s in mouse, hamster, guinea pig and rabbit are 2250, 140, 620, and 1000 mg/kg .
    Norbormide
  • HY-166807

    Biochemical Assay Reagents Others
    Palmitate-PEG-Mal (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Palmitate-PEG-Mal (MW 1000) can be used in drug delivery research .
    Palmitate-PEG-Mal (MW 1000)
  • HY-166968

    Biochemical Assay Reagents Others
    DSPE-PEG-COOH (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 5000) can be used in drug delivery research .
    DSPE-PEG-COOH (MW 5000)
  • HY-166979

    Biochemical Assay Reagents Others
    Stearic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 2000) can be used in drug delivery research .
    Stearic acid-mPEG (MW 2000)
  • HY-166980

    Biochemical Assay Reagents Others
    m-PEG-DPPE (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DPPE (MW 2000) can be used in drug delivery research .
    m-PEG-DPPE (MW 2000)
  • HY-166981

    Biochemical Assay Reagents Others
    DSPE-PEG-TCO (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-TCO (MW 2000) can be used in drug delivery research .
    DSPE-PEG-TCO (MW 2000)
  • HY-166982

    Biochemical Assay Reagents Others
    DSPE-PEG-PA (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-PA (MW 2000) can be used in drug delivery research .
    DSPE-PEG-PA (MW 2000)
  • HY-166983

    Biochemical Assay Reagents Others
    m-PEG-DMG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DMG (MW 5000) can be used in drug delivery research .
    m-PEG-DMG (MW 5000)
  • HY-167022

    Biochemical Assay Reagents Others
    DSPE-PEG-azide (MW 600) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-azide (MW 600) can be used in drug delivery research .
    DSPE-PEG-azide (MW 600)
  • HY-167028

    Biochemical Assay Reagents Others
    DSPE-PEG-alkyne (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-alkyne (MW 2000) can be used in drug delivery research .
    DSPE-PEG-alkyne (MW 2000)
  • HY-167031

    Biochemical Assay Reagents Others
    DOPE-PEG-DBCO (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG-DBCO (MW 5000) can be used in drug delivery research .
    DOPE-PEG-DBCO (MW 5000)
  • HY-167036

    Biochemical Assay Reagents Others
    DMG-PEG-Mal (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DMG-PEG-Mal (MW 2000) can be used in drug delivery research .
    DMG-PEG-Mal (MW 2000)
  • HY-W440825

    Biochemical Assay Reagents Others
    DSPE-PEG-COOH (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 1000) can be used in drug delivery research .
    DSPE-PEG-COOH (MW 1000)
  • HY-W440830

    Biochemical Assay Reagents Others
    DSPE-PEG-COOH (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 3400) can be used in drug delivery research .
    DSPE-PEG-COOH (MW 3400)
  • HY-W440881

    Biochemical Assay Reagents Others
    DSPE-PEG-DBCO (sodium) (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 3400) can be used in drug delivery research .
    DSPE-PEG-DBCO sodium (MW 3400)
  • HY-W440894

    Biochemical Assay Reagents Others
    DSPE-PEG-DBCO (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 5000) can be used in drug delivery research .
    DSPE-PEG-DBCO sodium (MW 5000)
  • HY-W440922

    Biochemical Assay Reagents Others
    m-PEG-DSPE (sodium) (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 1000) can be used in drug delivery research .
    m-PEG-DSPE sodium (MW 1000)
  • HY-W440924

    Biochemical Assay Reagents Others
    m-PEG-DSPE (sodium) (MW 3000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 3000) can be used in drug delivery research .
    m-PEG-DSPE sodium (MW 3000)
  • HY-W440925

    Biochemical Assay Reagents Others
    m-PEG-DSPE (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 5000) can be used in drug delivery research .
    m-PEG-DSPE sodium (MW 5000)
  • HY-W440930

    Biochemical Assay Reagents Others
    Stearic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 1000) can be used in drug delivery research .
    Stearic acid-mPEG (MW 1000)
  • HY-W440932

    Biochemical Assay Reagents Others
    Stearic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 5000) can be used in drug delivery research .
    Stearic acid-mPEG (MW 5000)
  • HY-W440941

    Biochemical Assay Reagents Others
    Pentacosadiynoic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 1000) can be used in drug delivery research .
    Pentacosadiynoic acid-mPEG (MW 1000)
  • HY-W440942

    Biochemical Assay Reagents Others
    Pentacosadiynoic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 2000) can be used in drug delivery research .
    Pentacosadiynoic acid-mPEG (MW 2000)
  • HY-W440943

    Biochemical Assay Reagents Others
    Pentacosadiynoic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 5000) can be used in drug delivery research .
    Pentacosadiynoic acid-mPEG (MW 5000)
  • HY-W591333

    Biochemical Assay Reagents Others
    m-PEG-DSPE (sodium) (MW 550) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 550) can be used in drug delivery research .
    m-PEG-DSPE sodium (MW 550)
  • HY-166871

    Biochemical Assay Reagents Others
    DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 5000) can be used in drug delivery research .
    DSPE-PEG-endo-BCN (MW 5000)
  • HY-166874

    Biochemical Assay Reagents Others
    DSPE-PEG-endo-BCN (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 2000) can be used in drug delivery research .
    DSPE-PEG-endo-BCN (MW 2000)
  • HY-166996

    Biochemical Assay Reagents Others
    Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine can be used in drug delivery research .
    Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine
  • HY-150701

    Glucocorticoid Receptor Mineralocorticoid Receptor 11β-HSD Metabolic Disease
    INCB13739 is an orally active, potent, selective and tissue-specific11β-HSD1 (11β-hydroxysteroid dehydrogenase 1) inhibitor, with IC50 values of 3.2 nM (11β-HSD1 enzymatic) and 1.1 nM (11β-HSD1 PBMC), respectively. INCB13739 can be used for type 2 diabetes mellitus (T2DM) and obesity research .
    INCB13739
  • HY-U00178

    CB7432

    Estrogen Receptor/ERR Cancer
    Idoxifene (CB7432) is a novel tissue-specific selective estrogen receptor modulator (SERM).
    Idoxifene
  • HY-P0237

    Kallikrein Cancer
    KKI-5 is a specific inhibitor of tissue kallikrein. KKI-5 can attenuate breast cancer cell invasion .
    KKI-5
  • HY-139852

    Phosphatase Cancer
    PLAP-IN-1 is a potent (IC50 = 32 nM) and selective PLAP inhibitor, with no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity.
    PLAP-IN-1
  • HY-P0237A

    Kallikrein Cancer
    KKI-5 (TFA) is a specific inhibitor of tissue kallikrein. KKI-5 (TFA) can attenuate breast cancer cell invasion .
    KKI-5 TFA
  • HY-164574

    Radionuclide-Drug Conjugates (RDCs) Cancer
    BCN-DOTA is a cyclooctyne-linked DOTA chelator that can be radiolabeled with zirconium-89 as a radionuclide-labeled drug conjugate (RDC) to target specific biomolecules, cells, or tissues.
    BCN-DOTA
  • HY-P2752

    LPL

    Endogenous Metabolite Metabolic Disease Cancer
    Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation .
    Lipoprotein lipase, Pseudomonas sp
  • HY-148796

    GE3126

    Fluorescent Dye Others
    Rizedisben (GE3126) is a fluorophore that can be used in fluorescence image-guided surgery. Rizedisben reduces non-specific adipose tissue fluorescence intensity and enhances nerve visibility .
    Rizedisben
  • HY-164577

    Radionuclide-Drug Conjugates (RDCs) Cancer
    BCN-DOTA-GA is a cyclooctyne-linked DOTA chelator that can be labeled with radioactive zirconium-89 and used as a radionuclide-labeled drug conjugate (RDC) to target specific biomolecules, cells or tissues.
    BCN-DOTA-GA
  • HY-125625

    Renin Cardiovascular Disease
    ES 6864 is an orally active, competitive inhibitor for human renin, with an IC50 of 6.9 nM and a Ki of 7.3 nM. ES 6864 exhibits high species-specific and enzyme-specific properties. ES 6864 exhibits metabolic stability in rat tissue homogenates. ES 6864 reduces blood pressure in rats and sodium-depleted awake marmosets .
    ES 6864
  • HY-106688A

    St-567 hydrobromide

    Others Cardiovascular Disease
    Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects .
    Alinidine hydrobromide
  • HY-141663

    ADC Linker Cancer
    2',3'-cGAMP-C2-SH is a cyclic di-nucleotide (CDN) that can be conjugated to antibodies or antigen-binding fragments targeting specific antigens in the microenvironment of diseased cells or tissue .
    2',3'-cGAMP-C2-SH
  • HY-136630

    SHR110008

    Others Others
    Felotaxel (SHR110008) is a compound with antitumor activity that has specific pharmacokinetic properties in rats and is rapidly distributed to normal tissues. The kidney is the major excretion organ, and its plasma protein binding capacity is nearly linearly related to concentration.
    Felotaxel
  • HY-11039

    HSP Cancer
    PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue .
    PU24FCl
  • HY-111895B
    Macropa-NH2 TFA
    3 Publications Verification

    Others Others
    Macropa-NH2 TFA is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases .
    Macropa-NH2 TFA
  • HY-111895A
    Macropa-NH2 hydrochloride
    3 Publications Verification

    Others Cancer
    Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases .
    Macropa-NH2 hydrochloride
  • HY-126969

    Others Metabolic Disease
    C333H is a selective PPARγ modulator with insulin-sensitizing and hypoglycemic activities. C333H exhibits similar insulin-sensitizing effects to thiazolidinediones (TZDs) in diabetic mouse models without significantly increasing body weight or adipose tissue weight. C333H increases circulating high molecular weight adiponectin isoform levels in diabetic db/db mice, reduces serine phosphorylation of PPARγ 273 in brown adipose tissue, and selectively modulates the expression of specific PPARγ target genes in adipose tissue. Express. C333H exhibits weak recruitment of co-activators and weak dissociation of co-repressors in vitro. These properties suggest that C333H may be a potential inhibitor of type 2 diabetes .
    C333H
  • HY-118816

    11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α

    Others Metabolic Disease
    11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
    11β-Prostaglandin F2α
  • HY-118716

    2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

    Others Cancer
    PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat . DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity .
    PhIP
  • HY-165116

    18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)

    Others Others
    1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.
    1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE
  • HY-P1597
    Malantide
    1 Publications Verification

    PKA PKC Cancer
    Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide is also an efficient substrate for PKC with a Km of 16 μM .
    Malantide
  • HY-P1597A

    PKA PKC Cancer
    Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide TFA is also an efficient substrate for PKC with a Km of 16 μM .
    Malantide TFA

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: