2. Metabolic Enzyme/Protease NF-κB
  3. MALT1
  4. SGR-1505

SGR-1505 is an orally active MALT1 allosteric inhibitor. SGR-1505 inhibits MALT1 enzymatic activity and shows anti-proliferative activity in BTK inhibitor (BTKi)-sensitive and BTKi-resistant activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines. SGR-1505 can be used for research of B-cell lymphomas.

For research use only. We do not sell to patients.

SGR-1505 Chemical Structure

SGR-1505 Chemical Structure

CAS No. : 2661481-41-8

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SGR-1505 Related Antibodies

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Description

SGR-1505 is an orally active MALT1 allosteric inhibitor. SGR-1505 inhibits MALT1 enzymatic activity and shows anti-proliferative activity in BTK inhibitor (BTKi)-sensitive and BTKi-resistant activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines. SGR-1505 can be used for research of B-cell lymphomas[1].

Molecular Weight

481.79

Formula

C18H12ClF4N9O
CAS No.
SMILES

FC(F)([C@]1(C2=C(C=NC3=CC(F)=NN32)N(C1)C(NC4=CN=C(N5N=CC=N5)C(Cl)=C4)=O)C)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SGR-1505 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SGR-15052661481-41-8SGR1505SGR 1505MALT1mucosa associated lymphoid tissue lymphoma translocation gene 1ABC-DLBCLB-cell lymphomasInhibitorinhibitorinhibit

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