2. PROTAC
  3. Ligands for E3 Ligase
  4. SJ6145

SJ6145 is a potent ligand for KLHDC2SBD, with the Kd of 16.9 μM in SPR test, IC50 value of 42 μM in inhibiting KLHDC2SBD binding to a di-Gly degron peptide test.

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SJ6145 Chemical Structure

SJ6145 Chemical Structure

CAS No. : 1010913-79-7

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SJ6145 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

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Description

SJ6145 is a potent ligand for KLHDC2SBD, with the Kd of 16.9 μM in SPR test, IC50 value of 42 μM in inhibiting KLHDC2SBD binding to a di-Gly degron peptide test[1].

IC50 & Target

KLHDC2

 

Molecular Weight

294.30

Formula

C13H11FN2O3S
CAS No.
SMILES

O=C(CNC(CC1=CSC(C2=C(C=CC=C2)F)=N1)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SJ6145 Related Classifications

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Keywords:

SJ61451010913-79-7SJ 6145SJ-6145Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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