2. Apoptosis
  3. RIP kinase
  4. TP-030-1

TP-030-1 is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases.

For research use only. We do not sell to patients.

TP-030-1 Chemical Structure

TP-030-1 Chemical Structure

CAS No. : 2095514-75-1

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TP-030-1 Related Antibodies

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Description

TP-030-1 is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases[1].

In Vitro

TP-030-1 inhibits HT29 necroptosis with an IC50 value of 18 nM[1].
TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM[1].
TP-030-1 inhibits mRIPK1 with an IC50 value of 4.2 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TP-030-1 Related Antibodies
Molecular Weight

402.45

Formula

C23H22N4O3
CAS No.
SMILES

O=C1[C@@H](N2CCC3=CN(CC4=CC=CC=C4)N=C3C2=O)COC5=CC=CC=C5N1C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TP-030-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TP-030-12095514-75-1RIP kinaseReceptor-interacting protein kinasesRIPKHT29inflammationprobeinhibitorneurodegenerative diseaseInhibitorinhibit

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