Trandolaprilate (Synonyms: Trandolaprilat; RU 44403)

Cat. No.: HY-A0116: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity.

For research use only. We do not sell to patients.

Trandolaprilate Chemical Structure

CAS No. : 87679-71-8

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Trandolaprilate:

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

402.48

Formula

C₂₂H₃₀N₂O₅

CAS No.

87679-71-8

SMILES

O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O

Structure Classification

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (310.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4846 mL	12.4230 mL	24.8460 mL
5 mM	0.4969 mL	2.4846 mL	4.9692 mL
10 mM	0.2485 mL	1.2423 mL	2.4846 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Millet D, et al. Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells. Eur J Biochem. 1992 Jun 1;206(2):367-72. [Content Brief]

[2]. Al-Hawash LA, et al. Stability-indicating HPLC determination of trandolapril in bulk drug and pharmaceutical dosage forms. Int J Anal Chem. 2015;2015:820517. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4846 mL	12.4230 mL	24.8460 mL	62.1149 mL
	5 mM	0.4969 mL	2.4846 mL	4.9692 mL	12.4230 mL
	10 mM	0.2485 mL	1.2423 mL	2.4846 mL	6.2115 mL
	15 mM	0.1656 mL	0.8282 mL	1.6564 mL	4.1410 mL
	20 mM	0.1242 mL	0.6211 mL	1.2423 mL	3.1057 mL
	25 mM	0.0994 mL	0.4969 mL	0.9938 mL	2.4846 mL
	30 mM	0.0828 mL	0.4141 mL	0.8282 mL	2.0705 mL
	40 mM	0.0621 mL	0.3106 mL	0.6211 mL	1.5529 mL
	50 mM	0.0497 mL	0.2485 mL	0.4969 mL	1.2423 mL
	60 mM	0.0414 mL	0.2070 mL	0.4141 mL	1.0352 mL
	80 mM	0.0311 mL	0.1553 mL	0.3106 mL	0.7764 mL
	100 mM	0.0248 mL	0.1242 mL	0.2485 mL	0.6211 mL

Trandolaprilate Related Classifications

Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trandolaprilate87679-71-8Trandolaprilat RU 44403RU44403RU 44403RU-44403Angiotensin-converting Enzyme (ACE)Endogenous Metaboliteangiotensin-converting enzymec-fossmooth muscle cellsmetabolitelipophilicityInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks