2. Vitamin D Related/Nuclear Receptor NF-κB
  3. Estrogen Receptor/ERR NF-κB
  4. WAY-169916

WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect.

For research use only. We do not sell to patients.

WAY-169916 Chemical Structure

WAY-169916 Chemical Structure

CAS No. : 669764-18-5

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5 mg USD 120 In-stock
10 mg USD 200 In-stock
25 mg USD 420 In-stock
50 mg USD 700 In-stock
100 mg USD 1150 In-stock
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Based on 1 publication(s) in Google Scholar

WAY-169916 Related Antibodies

Top Publications Citing Use of Products

View All Estrogen Receptor/ERR Isoform Specific Products:

View All Isoforms
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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Description

WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].

Molecular Weight

334.29

Formula

C17H13F3N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(C(O)=C1)C2=NN(C3=C2C=CC=C3C(F)(F)F)CC=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (373.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9914 mL 14.9571 mL 29.9141 mL
5 mM 0.5983 mL 2.9914 mL 5.9828 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9914 mL 14.9571 mL 29.9141 mL 74.7854 mL
5 mM 0.5983 mL 2.9914 mL 5.9828 mL 14.9571 mL
10 mM 0.2991 mL 1.4957 mL 2.9914 mL 7.4785 mL
15 mM 0.1994 mL 0.9971 mL 1.9943 mL 4.9857 mL
20 mM 0.1496 mL 0.7479 mL 1.4957 mL 3.7393 mL
25 mM 0.1197 mL 0.5983 mL 1.1966 mL 2.9914 mL
30 mM 0.0997 mL 0.4986 mL 0.9971 mL 2.4928 mL
40 mM 0.0748 mL 0.3739 mL 0.7479 mL 1.8696 mL
50 mM 0.0598 mL 0.2991 mL 0.5983 mL 1.4957 mL
60 mM 0.0499 mL 0.2493 mL 0.4986 mL 1.2464 mL
80 mM 0.0374 mL 0.1870 mL 0.3739 mL 0.9348 mL
100 mM 0.0299 mL 0.1496 mL 0.2991 mL 0.7479 mL
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WAY-169916 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-169916669764-18-5WAY169916WAY 169916Estrogen Receptor/ERRNF-κBNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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