(Z)-Aconitic acid (Synonyms: cis-Aconitic acid)

Name: (Z)-Aconitic acid
Brand: MedChemExpress
SKU: HY-W016814
Rating: 4.5 (1 reviews)

Cat. No.: HY-W016814 Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(Z)-Aconitic acid (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.

For research use only. We do not sell to patients.

(Z)-Aconitic acid Chemical Structure

CAS No. : 585-84-2

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 196	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (Z)-Aconitic acid:

1 Publications Citing Use of MCE (Z)-Aconitic acid

•J Agric Food Chem. 2021 Nov 18. [Abstract]

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•Related Small Molecules:

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Biological Activity
Purity & Documentation
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

174.11

Formula

C₆H₆O₆

CAS No.

585-84-2

Appearance

Solid

Color

White to light yellow

SMILES

O=C(O)/C([H])=C(C(O)=O)/CC(O)=O.

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (574.35 mM; Need ultrasonic)

DMSO : ≥ 100 mg/mL (574.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.7435 mL	28.7175 mL	57.4350 mL
5 mM	1.1487 mL	5.7435 mL	11.4870 mL
10 mM	0.5743 mL	2.8717 mL	5.7435 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (14.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (574.35 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (247 KB) SDS (557 KB)

COA (248 KB) HNMR (233 KB) RP-HPLC (205 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	5.7435 mL	28.7175 mL	57.4350 mL	143.5874 mL
	5 mM	1.1487 mL	5.7435 mL	11.4870 mL	28.7175 mL
	10 mM	0.5743 mL	2.8717 mL	5.7435 mL	14.3587 mL
	15 mM	0.3829 mL	1.9145 mL	3.8290 mL	9.5725 mL
	20 mM	0.2872 mL	1.4359 mL	2.8717 mL	7.1794 mL
	25 mM	0.2297 mL	1.1487 mL	2.2974 mL	5.7435 mL
	30 mM	0.1914 mL	0.9572 mL	1.9145 mL	4.7862 mL
	40 mM	0.1436 mL	0.7179 mL	1.4359 mL	3.5897 mL
	50 mM	0.1149 mL	0.5743 mL	1.1487 mL	2.8717 mL
	60 mM	0.0957 mL	0.4786 mL	0.9572 mL	2.3931 mL
	80 mM	0.0718 mL	0.3590 mL	0.7179 mL	1.7948 mL
	100 mM	0.0574 mL	0.2872 mL	0.5743 mL	1.4359 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

(Z)-Aconitic acid Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-Aconitic acid585-84-2cis-Aconitic acidEndogenous MetaboliteInhibitorinhibitorinhibit

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(Z)-Aconitic acid (Synonyms: cis-Aconitic acid)

Customer Review

Other Forms of (Z)-Aconitic acid:

(Z)-Aconitic acid Related Antibodies

1 Publications Citing Use of MCE (Z)-Aconitic acid

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

(Z)-Aconitic acid Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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