2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1406
    6-Methylcoumarin
    		99.99%
    6-Methylcoumarin is a synthetic fragrance widely used in cosmetics.
    6-Methylcoumarin
  • HY-147319
    RTI-7470-44
    		99.85%
    RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinson’s disease (PD).
    RTI-7470-44
  • HY-163084
    HJ445A
    		98.31%
    HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research.
    HJ445A
  • HY-153359
    M3913
    		99.54%
    M3913 is an antitumor compound. M3913 has antiproliferation activity against cancer cells.
    M3913
  • HY-111895B
    Macropa-NH2 TFA
    		98.03%
    Macropa-NH2 TFA is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases.
    Macropa-NH2 TFA
  • HY-131062
    yGsy2p-IN-1
    		98.69%
    yGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p). yGsy2p-IN-1 is a competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1. yGsy2p-IN-H23 a pyrazole inhibitor, is used for glycogen storage diseases (GSDs).
    yGsy2p-IN-1
  • HY-112097
    E260
    		Inhibitor 99.05%
    E260 is a Fer/FerT kinase inhibitor.
    E260
  • HY-107150
    Reproxalap
    		98.85%
    Reproxalap (ADX-102) is an active aldehyde sequestering agent. Reproxalap reduces the PKCα activity. Reproxalap blocks caspase 3/7 activation. Reproxalap protects cells from the cytotoxicity of C18:0-al. Reproxalap has anti-inflammatory and pain-relieving effects. Reproxalap is used in studies of dry eye, allergic conjunctivitis, and non-infectious anterior uveitis.
    Reproxalap
  • HY-110329
    ML179
    		Agonist 99.83%
    ML179 (SR-1309) is a inverse LRH1/NR5A2 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer.
    ML179
  • HY-148508
    PhosTAC3
    		99.97%
    PhosTAC3 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with three PEG groups. PhosTAC3 induces dephosphorylation of PDCD4 and FOXO3a.
    PhosTAC3
  • HY-112514
    1,3,6,8-Tetrahydroxynaphthalene
    		98.82%
    1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin.
    1,3,6,8-Tetrahydroxynaphthalene
  • HY-112431A
    Carnostatine hydrochloride
    		Inhibitor 99.81%
    Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent and selective carnosinase 1 (CN1) inhibitor with a Ki of 11 nM for human recombinant CN1. Carnostatine hydrochloride can be used for the treatment of diabetic nephropathy (DN).
    Carnostatine hydrochloride
  • HY-153074
    ISR-IN-1
    		98.25%
    ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM).
    ISR-IN-1
  • HY-12462
    WS3
    		98.00%
    WS3?is a novel proliferative molecule that promotes pancreatic β cell proliferation in rodent and human primary islets. WS3?can be used for the research of type 1 diabetes.
    WS3
  • HY-106844A
    (+)-EMD 57033
    		99.72%
    (+)-EMD 57033 is a cardiac troponin C (cTnC) activator, is a dominant Ca2+ sensitizer. (+)-EMD 57033 binds the cardiac/slow skeletal troponin C isoform and exerts myocardial contractile promotion function.
    (+)-EMD 57033
  • HY-152189
    S19-1035
    		99.77%
    S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC50 value of 3.04 nM. S19-1035 can be used for the research of tumor.
    S19-1035
  • HY-160424
    DEANO sodium
    DEANO sodium is notric oxide donor. DEANO sodium potentiates the abilitv of hypoxanthine/xanthine oxidase to induce lipid peroxidation as well as DNA single- and double-strand breaks.
    DEANO sodium
  • HY-147240
    Acloproxalap
    		98.79%
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes.
    Acloproxalap
  • HY-118090
    L-γ-Glutamyl-L-glutamic acid
    		99.72%
    L-γ-Glutamyl-L-glutamic acid is the isomer of D-γ-Glutamyl-D-glutamic acid (HY-118090A), and can be used as an experimental control. D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
    L-γ-Glutamyl-L-glutamic acid
  • HY-100303A
    FR194738
    		Inhibitor 99.81%
    FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
    FR194738
Cat. No. Product Name / Synonyms Application Reactivity