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  3. Antibiotic Fungal
  4. Anticancer agent 151

Anticancer agent 151 (compound 6C) is an anticancer agent. Anticancer agent 151 exhibits excellent in vitro cytotoxic activity against MCF-7 cells with an IC50 value of 6.3 μM.

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Anticancer agent 151 Chemical Structure

Anticancer agent 151 Chemical Structure

CAS No. : 1227476-97-2

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Anticancer agent 151 Related Antibodies

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Description

Anticancer agent 151 (compound 6C) is an anticancer agent. Anticancer agent 151 exhibits excellent in vitro cytotoxic activity against MCF-7 cells with an IC50 value of 6.3 μM[1].

Cellular Effect
Cell Line Type Value Description References
K562 IC50
> 10 μM
Compound: 6c
Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
[PMID: 23981532]
MCF7 IC50
7.9 μM
Compound: 6c
Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
[PMID: 23981532]
Molecular Weight

429.30

Formula

C22H18Cl2N2O3
CAS No.
SMILES

O=C(C1=C(C=CC(Cl)=C1)O)N[C@H](C(NC2=CC=C(C=C2)Cl)=O)CC3=CC=CC=C3
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anticancer agent 151 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1511227476-97-2Anticancer agent151Anticancer agent-151AntibioticFungalCytotoxicityCancerMCF-7Inhibitorinhibitorinhibit

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