ER proteostasis regulator-1

Cat. No.: HY-153010 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

ER proteostasis regulator-1 (compound 481) is a potent ER proteostasis regulator. ER proteostasis regulator-1 has the potential for the research of Alzheimer's disease and diabetes.

For research use only. We do not sell to patients.

ER proteostasis regulator-1 Chemical Structure

CAS No. : 912777-95-8

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
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100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

ER proteostasis regulator-1 (compound 481) is a potent ER proteostasis regulator. ER proteostasis regulator-1 has the potential for the research of Alzheimer's disease and diabetes^[1].

Molecular Weight

314.38

Formula

C₁₈H₂₂N₂O₃

CAS No.

912777-95-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C(CCCC1C)C)C2=NOC(C3=CC=C(OC)C=C3)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (318.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1809 mL	15.9043 mL	31.8086 mL
5 mM	0.6362 mL	3.1809 mL	6.3617 mL
10 mM	0.3181 mL	1.5904 mL	3.1809 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (268 KB) SDS (251 KB)

COA (248 KB) HNMR (153 KB)

Handling Instructions (2659 KB)

References

[1]. Christina COOLEY, et al. Regulators of the endoplasmic reticulum proteostasis network. WO2017117430A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1809 mL	15.9043 mL	31.8086 mL	79.5216 mL
	5 mM	0.6362 mL	3.1809 mL	6.3617 mL	15.9043 mL
	10 mM	0.3181 mL	1.5904 mL	3.1809 mL	7.9522 mL
	15 mM	0.2121 mL	1.0603 mL	2.1206 mL	5.3014 mL
	20 mM	0.1590 mL	0.7952 mL	1.5904 mL	3.9761 mL
	25 mM	0.1272 mL	0.6362 mL	1.2723 mL	3.1809 mL
	30 mM	0.1060 mL	0.5301 mL	1.0603 mL	2.6507 mL
	40 mM	0.0795 mL	0.3976 mL	0.7952 mL	1.9880 mL
	50 mM	0.0636 mL	0.3181 mL	0.6362 mL	1.5904 mL
	60 mM	0.0530 mL	0.2651 mL	0.5301 mL	1.3254 mL
	80 mM	0.0398 mL	0.1988 mL	0.3976 mL	0.9940 mL
	100 mM	0.0318 mL	0.1590 mL	0.3181 mL	0.7952 mL