IGF1R - insulin like growth factor 1 receptor Gene

Macaca fascicularis

Gene ID: 102130142 | Gene type: protein coding

About IGF1R

Primary_assembly 7: 77,820,352-78,131,628 forward strand.Macaca_fascicularis_6.0:CM021945.1

This gene has 1 transcript (splice variant), 276 orthologues and 55 paralogues.

mRNA	Protein	Name
XM_045397462.1	XP_045253397.1	insulin-like growth factor 1 receptor isoform X3
XM_005560575.3	XP_005560632.1	insulin-like growth factor 1 receptor isoform X1
XM_005560576.3	XP_005560633.1	insulin-like growth factor 1 receptor isoform X2

Recep_L_domain

Furin-like

Recep_L_domain

FN3

PTKc_InsR_like

Protein Preferred Names

Protein Names

insulin-like growth factor 1 receptor

Cat. No.	Product Name	Accession	Purity
HY-P78586	IGF-I R Protein, Cynomolgus (HEK293, His)	G7P9I7 (E31-N908)	≥95%

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15656	Ceritinib	Inhibitor	99.98%	Yes
HY-15656A	Ceritinib dihydrochloride	Inhibitor	99.57%	Yes
HY-B0025	Voglibose	Inhibitor	≥98.0%	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99165	Teprotumumab	Inhibitor	99.46%	Unkown

Clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-15494	Picropodophyllin		99.85%	Phase 2
HY-10200	BMS-754807	Inhibitor	99.41%	Phase 2
HY-15749	XL228	Inhibitor	99.64%	Phase 1
HY-B0794B	AZ7550 Mesylate	Inhibitor	99.24%	Phase 1
HY-13326	ASP3026		99.88%	Phase 1
HY-B0794	AZ7550	Inhibitor	/	Phase 1
HY-B0794A	AZ7550 hydrochloride	Inhibitor	98.66%	Phase 1

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99294	Ganitumab	Inhibitor	96.00%	Phase 3
HY-P99197	Figitumumab	Inhibitor	96.89%	Phase 3
HY-P99284	Dalotuzumab		97.43%	Phase 2
HY-P99218	Robatumumab	Inhibitor	/	Phase 2
HY-P99712	Lonigutamab	Inhibitor	95.00%	Phase 2
HY-P99672	Istiratumab	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (30)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-116624	MAZ51		99.96%	Unkown
HY-10262	BMS-536924		99.83%	Unkown
HY-50866	NVP-AEW541		99.92%	Unkown
HY-15609	AZD-3463		99.58%	Unkown
HY-10252	NVP-ADW742		99.54%	Unkown
HY-N0908	Ginsenoside Rg5		99.87%	Unkown
HY-10524	GSK1904529A		99.66%	Unkown
HY-10253	AG1024		99.82%	Unkown
HY-13203	NVP-TAE 226		99.77%	Unkown
HY-100349	SU4312	Inhibitor	99.76%	Unkown
HY-18785	Indirubin Derivative E804	Inhibitor	98.54%	Unkown
HY-135680	I-OMe-Tyrphostin AG 538	Inhibitor	98.03%	Unkown
HY-145110	IGF-1R inhibitor-2	Inhibitor	98.36%	Unkown
HY-125102	AZ12253801	Inhibitor	/	Unkown
HY-50866B	NVP-AEW541 dihydrochloride		/	Unkown
HY-108230	ALK-IN-12	Inhibitor	/	Unkown
HY-15494S1	Picropodophyllin-d6		/	Unkown
HY-156914	IGF-1R/SRC-IN-1	Inhibitor	99.86%	Unkown
HY-162506	IGF-1R inhibitor-3	Inhibitor	/	Unkown
HY-167854	KW-2450 free base		/	Unkown
HY-402309	IGF-1R modulator 1	Modulator	/	Unkown
HY-B0794S	AZ7550-d5	Inhibitor	/	Unkown
HY-RS06615	IGF1R Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06616	Igf1r Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06617	Igf1r Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-100349A	cis-SU4312	Inhibitor	/	Unkown
HY-14357	BMS 695735	Inhibitor	/	Unkown
HY-168616	CL-A3-7	Inhibitor	/	Unkown
HY-21291	SU-4313	Modulator	/	Unkown
HY-N6611	Chimaphilin	Inhibitor	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990084	Veligrotug	Inhibitor	99.25%	Unkown

Species	Symbol	Source	ID
Homo sapiens	IGF1R	NCBI	NCBI:3480
Mus musculus	IGF1R	NCBI	NCBI:16001
Rattus norvegicus	IGF1R	NCBI	NCBI:25718

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