TMEM182 - transmembrane protein 182 Gene

Homo sapiens

Gene ID: 130827 | Gene type: protein coding

About TMEM182

This gene has 11 transcripts (splice variants) and 253 orthologues. Biased expression in heart (RPKM 27.0), prostate (RPKM 2.7) and 2 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM182 Products(5)

mRNA	Protein	Name
NM_001321343.2	NP_001308272.2	transmembrane protein 182 isoform b
NM_001321344.2	NP_001308273.2	transmembrane protein 182 isoform b
NM_001321345.2	NP_001308274.2	transmembrane protein 182 isoform c
NM_001321346.2	NP_001308275.2	transmembrane protein 182 isoform d
NM_144632.5	NP_653233.5	transmembrane protein 182 isoform a precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM182 Protein Structure

Claudin_2

0
100
200
229 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 182

TMEM182 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TMEM182	Q6ZP80	LGALS3	Homo sapiens	P17931	Anti Tag CoIP	33961781
Intra	TMEM182	Q6ZP80	LGALS3	Homo sapiens	P17931	Anti Tag CoIP	28514442
Intra	TMEM182	Q6ZP80	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	TMEM182	Q6ZP80	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	PLP1	Homo sapiens	P60201-2	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	PLP1	Homo sapiens	P60201-2	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	MS4A3	Homo sapiens	Q96HJ5	Validated Y2H	32296183
Intra	TMEM182	Q6ZP80	MS4A3	Homo sapiens	Q96HJ5	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	MS4A3	Homo sapiens	Q96HJ5	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	GJA8	Homo sapiens	P48165	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	GJA8	Homo sapiens	P48165	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	GPR42	Homo sapiens	O15529	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	GPR42	Homo sapiens	O15529	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	SUSD3	Homo sapiens	Q96L08	Validated Y2H	32296183
Intra	TMEM182	Q6ZP80	SUSD3	Homo sapiens	Q96L08	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	SUSD3	Homo sapiens	Q96L08	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	CLDN5	Homo sapiens	O00501	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	CLDN5	Homo sapiens	O00501	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	TSPAN12	Homo sapiens	O95859	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	TSPAN12	Homo sapiens	O95859	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	TMEM140	Homo sapiens	Q9NV12	Validated Y2H	32296183
Intra	TMEM182	Q6ZP80	SYNE4	Homo sapiens	Q8N205	Validated Y2H	25416956
Intra	TMEM182	Q6ZP80	SMIM3	Homo sapiens	Q9BZL3	Y2H Prey Pooling	32296183
Intra	TMEM182	Q6ZP80	SMIM3	Homo sapiens	Q9BZL3	Validated Y2H	32296183
Intra	TMEM182	Q6ZP80	SMIM3	Homo sapiens	Q9BZL3	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	KLRC1	Homo sapiens	P26715	Y2H Array	32296183
Intra	TMEM182	Q6ZP80	KLRC1	Homo sapiens	P26715	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14689	TMEM182 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TMEM182	VGNC	VGNC:36008
Canis familiaris	TMEM182	VGNC	VGNC:47507
Macaca mulatta	TMEM182	VGNC	VGNC:79604
Mus musculus	TMEM182	MGD	MGI:1923725
Rattus norvegicus	TMEM182	RGD	RGD:1563696
Felis catus	TMEM182	VGNC	VGNC:66297

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