2. Gene
  3. SMIM3 - small integral membrane protein 3 Gene

SMIM3 - small integral membrane protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NID67; MST150; C5orf62

Gene ID: 85027 | Gene type: protein coding

About SMIM3

Cytogenetic location: 5q33.1 Genomic coordinates (GRCh38): 5:150,778,757-150,796,734 (from NCBI)

This gene has 2 transcripts (splice variants) and 108 orthologues. Broad expression in fat (RPKM 64.3), bone marrow (RPKM 21.5) and 18 other tissues.

Summary

Enables identical protein binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SMIM3 Products(1)

mRNA Protein Name
NM_032947.5 NP_116565.3 small integral membrane protein 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small integral membrane protein 3

NGF-induced differentiation clone 67 protein

SMIM3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra SMIM3 Q9BZL3 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
Intra SMIM3 Q9BZL3 TEX264 Homo sapiens Q9Y6I9
Y2H Array
32296183
Intra SMIM3 Q9BZL3 TEX264 Homo sapiens Q9Y6I9
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 TEX264 Homo sapiens Q9Y6I9
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra SMIM3 Q9BZL3 SLC22A1 Homo sapiens O15245
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 SLC22A1 Homo sapiens O15245
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CLEC17A Homo sapiens Q6ZS10
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CLEC17A Homo sapiens Q6ZS10
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 CLEC7A Homo sapiens Q9BXN2-6
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 CLEC7A Homo sapiens Q9BXN2-6
Y2H Array
32296183
Intra SMIM3 Q9BZL3 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra SMIM3 Q9BZL3 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
Intra SMIM3 Q9BZL3 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ASGR2 Homo sapiens P07307-3
Y2H Array
32296183
Intra SMIM3 Q9BZL3 ASGR2 Homo sapiens P07307-3
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ATP1B4 Homo sapiens Q9UN42
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ATP1B4 Homo sapiens Q9UN42
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 ATP1B4 Homo sapiens Q9UN42
Y2H Array
32296183
Intra SMIM3 Q9BZL3 TM4SF18 Homo sapiens Q96CE8
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 TM4SF18 Homo sapiens Q96CE8
Y2H Array
32296183
Intra SMIM3 Q9BZL3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra SMIM3 Q9BZL3 KIR3DL3 Homo sapiens Q8N743
Y2H Array
32296183
Intra SMIM3 Q9BZL3 KIR3DL3 Homo sapiens Q8N743
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
Intra SMIM3 Q9BZL3 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Array
32296183
Intra SMIM3 Q9BZL3 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra SMIM3 Q9BZL3 LPAR6 Homo sapiens P43657
Y2H Array
32296183
Intra SMIM3 Q9BZL3 LPAR6 Homo sapiens P43657
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
25416956
Intra SMIM3 Q9BZL3 PNMA1 Homo sapiens Q8ND90
Validated Y2H
25416956
Intra SMIM3 Q9BZL3 PNMA1 Homo sapiens Q8ND90
Y2H Array
25416956
Intra SMIM3 Q9BZL3 IFNGR2 Homo sapiens P38484
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 IFNGR2 Homo sapiens P38484
Y2H Array
32296183
Intra SMIM3 Q9BZL3 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra SMIM3 Q9BZL3 MAL Homo sapiens P21145
Validated Y2H
25416956
Intra SMIM3 Q9BZL3 EMP1 Homo sapiens P54849
Validated Y2H
25416956
Intra SMIM3 Q9BZL3 EMP1 Homo sapiens P54849
Y2H Prey Pooling
25416956
Intra SMIM3 Q9BZL3 SGCB Homo sapiens Q16585
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 SGCB Homo sapiens Q16585
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CD53 Homo sapiens P19397
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra SMIM3 Q9BZL3 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ATP6V0C Homo sapiens P27449
Y2H Prey Pooling
25416956
Intra SMIM3 Q9BZL3 ATP6V0C Homo sapiens P27449
Y2H Array
25416956
Intra SMIM3 Q9BZL3 LZTS2 Homo sapiens Q9BRK4
Y2H Array
25416956
Intra SMIM3 Q9BZL3 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
25416956
Intra SMIM3 Q9BZL3 BSCL2 Homo sapiens Q96G97
Y2H Prey Pooling
25416956
Intra SMIM3 Q9BZL3 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra SMIM3 Q9BZL3 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra SMIM3 Q9BZL3 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra SMIM3 Q9BZL3 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 SLC38A1 Homo sapiens Q9H2H9
Validated Y2H
32296183
Intra SMIM3 Q9BZL3 SLC38A1 Homo sapiens Q9H2H9
Y2H Array
32296183
Intra SMIM3 Q9BZL3 SLC38A1 Homo sapiens Q9H2H9
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13437 SMIM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SMIM3 MGD MGI:1917088
Canis familiaris SMIM3 VGNC VGNC:46562
Felis catus SMIM3 VGNC VGNC:102325
Bos taurus SMIM3 VGNC VGNC:35021
Rattus norvegicus SMIM3 RGD RGD:628864