1. Gene
  2. Gal - galanin and GMAP prepropeptide Gene

Gal - galanin and GMAP prepropeptide Gene

Mus musculus

Also known as Galn

Gene ID: 14419 | Gene type: protein coding

About Gal

Summary

This gene encodes a neuroendocrine peptide that is principally produced by a subpopulation of lactotrophs in the pituitary gland. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: Galanin and Galanin message-associated peptide (GMAP). Mice lacking the encoded protein fail to lactate sufficiently due to abnormalities in the expression of Prolactin and lactotroph proliferation, exhibit attenuated chronic neuropathic pain and developmental deficits in the dorsal root ganglion neurons. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature proteins. [provided by RefSeq, Jul 2016]

Gal Products(2)

mRNA Protein Name
NM_001329667.1 NP_001316596.1 galanin peptides isoform 2 precursor
NM_010253.4 NP_034383.1 galanin peptides isoform 1 preproprotein
Protein Preferred Names Protein Names

galanin peptides

galanin

Orthologs Information

Species Symbol Source ID
Homo sapiens Gal NCBI NCBI:51083
Macaca fascicularis Gal NCBI NCBI:102144812
Rattus norvegicus Gal NCBI NCBI:29141