1. Gene
  2. CNIH3 - cornichon family AMPA receptor auxiliary protein 3 Gene

CNIH3 - cornichon family AMPA receptor auxiliary protein 3 Gene

Homo sapiens

Also known as CNIH-3

Gene ID: 149111 | Gene type: protein coding

About CNIH3

This gene has 14 transcripts (splice variants), 194 orthologues and 4 paralogues. Biased expression in brain (RPKM 4.8), testis (RPKM 1.6) and 10 other tissues.

Summary

Predicted to enable channel regulator activity. Involved in regulation of AMPA Receptor activity. Predicted to be located in dendritic shaft and postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in dendrite and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

CNIH3 Products(5)

mRNA Protein Name
NM_001322302.2 NP_001309231.1 protein cornichon homolog 3 isoform 2
NM_001322303.2 NP_001309232.1 protein cornichon homolog 3 isoform 3
NM_001322304.2 NP_001309233.1 protein cornichon homolog 3 isoform 4
NM_001322305.2 NP_001309234.1 protein cornichon homolog 3 isoform 5
NM_152495.2 NP_689708.1 protein cornichon homolog 3 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
20805473 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNIH3 Protein Structure

Cornichon

Cornichon: Cornichon protein (1 - 48)

Cornichon

Cornichon: Cornichon protein (59 - 152)

  • 0
  • 100
  • 160 a.a.
Protein Preferred Names Protein Names

protein cornichon homolog 3

cornichon homolog 3

Related Diseases

Diseases Alias
Splenic Artery Aneurysm

Aneurysm Of Splenic Artery

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris CNIH3 VGNC VGNC:39401
Macaca mulatta CNIH3 VGNC VGNC:71359
Felis catus CNIH3 VGNC VGNC:107860
Rattus norvegicus CNIH3 RGD RGD:1582859
Mus musculus CNIH3 MGD MGI:1920228
Bos taurus CNIH3 VGNC VGNC:27503