2. Gene
  3. Hp - haptoglobin Gene

Hp - haptoglobin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ba1-647

Gene ID: 24464 | Gene type: protein coding

About Hp

Summary

Enables hemoglobin binding activity and identical protein binding activity. Involved in several processes, including response to X-ray; response to growth hormone; and response to vitamin. Located in Golgi apparatus; blood microparticle; and endoplasmic reticulum. Used to study obesity and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); hepatocellular adenoma; kidney failure (multiple); and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in Plasmodium falciparum malaria; artery disease (multiple); gout; hemolytic anemia; and hyperglycemia. Orthologous to several human genes including HP (haptoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Hp Products(1)

mRNA Protein Name
NM_012582.2 NP_036714.2 haptoglobin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables hemoglobin binding IDA
IDA: Inferred from direct assay
6279649 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
6863267 RGD
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
12379430 RGD
involved in liver development IDA
IDA: Inferred from direct assay
16172914 RGD
involved in response to L-ascorbic acid IEP
IEP: Inferred from expression pattern
9566989 RGD
involved in response to X-ray IEP
IEP: Inferred from expression pattern
12379430 RGD
involved in response to cobalamin IEP
IEP: Inferred from expression pattern
12769818 RGD
involved in response to dimethyl sulfoxide IEP
IEP: Inferred from expression pattern
14757319 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
9435654 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
9749840 RGD
involved in response to growth hormone IEP
IEP: Inferred from expression pattern
16127721 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
3094379 RGD
involved in response to lead ion IEP
IEP: Inferred from expression pattern
9082656 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
16968543 RGD
involved in response to magnesium ion IEP
IEP: Inferred from expression pattern
11300617 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
15856910 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
19053136 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15899029 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
9432136 RGD
Cellular Component GO Annotation Evidence Reference Source
located in blood microparticle IDA
IDA: Inferred from direct assay
22014850 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
17161237 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

haptoglobin

liver regeneration-related protein LRRG173

zonulin

Recombinant Hp Proteins

Cat. No. Product Name Accession Purity
HY-P73934 Haptoglobin Protein, Rat (HEK293, His) P06866 (M1-N347) ≥95%

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101588 Gefapixant Antagonist 99.33% Yes
HY-17410 Iloperidone Antagonist 99.97% Unkown
HY-101588A Gefapixant citrate Antagonist 99.23% Unkown
HY-B0933A Gadoteridol pentahydrate / Unkown
HY-17410A Iloperidone hydrochloride Antagonist / Unkown
Clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-101103 HP-β-CD 99.74% Phase 3
HY-127165 Velnacrine Inhibitor / Phase 3
HY-123857 JNJ-55308942 Antagonist 99.92% Phase 2
HY-117508 JNJ-54175446 Antagonist 99.30% Phase 2
Pre-clinical Phase
Bioactive Molecules (40)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114364 UDP-Galactose disodium Agonist 99.42% Unkown
HY-136026 Camlipixant Antagonist 99.94% Unkown
HY-15568 A-317491 Antagonist 98.77% Unkown
HY-151480 HP590 98.59% Unkown
HY-110329 ML179 Agonist 99.83% Unkown
HY-15568A A-317491 sodium salt hydrate Antagonist 99.88% Unkown
HY-P1397A RVD-Hpα TFA Agonist 99.32% Unkown
HY-154840 4-Thiouridine 5′-triphosphate tetralithium Agonist / Unkown
HY-146564A HP210 Modulator 98.96% Unkown
HY-W011246 Velnacrine maleate Inhibitor ≥98.0% Unkown
HY-W050088 Isoxepac 99.92% Unkown
HY-146564 R-HP210 98.21% Unkown
HY-E70058 α-1-3,4 Fucosyltransferase, helicobacter pylori 90.00% Unkown
HY-127165S2 Velnacrine-d4 hydrochloride 98.60% Unkown
HY-127165S Velnacrine-d3 / Unkown
HY-17410S Iloperidone-d3 Antagonist / Unkown
HY-106508 Fendosal Inhibitor / Unkown
HY-127165S1 Velnacrine-d3 maleate / Unkown
HY-127165S3 Velnacrine-d4 / Unkown
HY-136092 Androsta-1,4,6-triene-3,17-dione Inhibitor / Unkown
HY-143576 P2X3 antagonist 37 Antagonist / Unkown
HY-145690 HP1328 Inhibitor / Unkown
HY-145691 HP1142 Inhibitor / Unkown
HY-146561 S-HP210 Modulator 98.12% Unkown
HY-150524 UDP-Galactose Agonist / Unkown
HY-153710 P2X3 antagonist 38 Antagonist / Unkown
HY-15376 Besipirdine Antagonist / Unkown
HY-154840A 4-Thiouridine 5′-triphosphate tetrasodium Agonist / Unkown
HY-167855 MRS4833 Antagonist / Unkown
HY-17410S1 Iloperidone-d3 hydrochloride Antagonist / Unkown
HY-P10539 Hp1404 Inhibitor / Unkown
HY-P1397 RVD-Hpα Agonist / Unkown
HY-RS06331 HP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06332 HP1BP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W050088S Isoxepac-d6 / Unkown
HY-105463 Saptomycin D Inhibitor / Unkown
HY-106016 HP 184 Activator / Unkown
HY-14607 Besipirdine hydrochloride Inhibitor / Unkown
HY-168117 HP-101 Inhibitor / Unkown
HY-108668 TC-P 262 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hp NCBI NCBI:3240
Canis familiaris Hp NCBI
Felis catus Hp NCBI NCBI:100144610
Macaca fascicularis Hp NCBI
Mus musculus Hp NCBI NCBI:15439
Susscrofa domestica Hp NCBI
Macaca mulatta Hp NCBI NCBI:706640