2. Gene
  3. Scd - stearoyl-CoA desaturase Gene

Scd - stearoyl-CoA desaturase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Scd1

Gene ID: 246074 | Gene type: protein coding

About Scd

Primary_assembly 1: 243,269,747-243,282,562 reverse strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 29 orthologues, 3 paralogues and is associated with 16 phenotypes. Biased expression in Liver (RPKM 4781.4), Adrenal (RPKM 4523.2) and 5 other tissues.

Summary

Enables iron ion binding activity and stearoyl-CoA 9-desaturase activity. Involved in response to fatty acid and unsaturated fatty acid biosynthetic process. Located in intracellular membrane-bounded organelle. Is integral component of membrane. Used to study carcinoma. Biomarker of hyperinsulinism. Orthologous to human SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Apr 2022]

Scd Products(1)

mRNA Protein Name
NM_139192.2 NP_631931.2 acyl-CoA desaturase 1

Scd Protein Structure

Delta9-FADS-like

Delta9-FADS-like: cd03505 (98 - 335)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
Protein Preferred Names Protein Names

acyl-CoA desaturase 1

delta(9)-desaturase 1

fatty acid desaturase 1

stearoyl-CoA desaturase 1

stearoyl-Coenzyme A desaturase 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18681 Voxelotor Inhibitor 99.97% Yes
Clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-19796 Icomidocholic acid ≥99.0% Phase 3
HY-13070 MK-8245 Inhibitor 99.04% Phase 2
HY-13077 MK-8245 Trifluoroacetate Inhibitor 98.09% Phase 2
HY-19762 GSK1940029 Inhibitor 99.82% Phase 1
Pre-clinical Phase
Bioactive Molecules (41)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-50709 A939572 Inhibitor 99.98% Unkown
HY-15823 CAY10566 Inhibitor 99.82% Unkown
HY-15822 MF-438 Inhibitor 99.92% Unkown
HY-15700 PluriSIn 1 99.84% Unkown
HY-12756A E6446 dihydrochloride 99.96% Unkown
HY-124751 YTX-465 Inhibitor 99.06% Unkown
HY-124876 SynuClean-D 99.89% Unkown
HY-N6807 Elemicin Inhibitor 99.22% Unkown
HY-148788 Osivelotor 99.83% Unkown
HY-124346 T-3364366 Inhibitor 99.73% Unkown
HY-100249 XEN723 Inhibitor 99.90% Unkown
HY-127143 Sterculic acid Inhibitor ≥99.0% Unkown
HY-P3180 Hemoglobin S ≥99.0% Unkown
HY-141525 SCD1 inhibitor-4 Inhibitor 98.93% Unkown
HY-11034 CVT-12012 Inhibitor 99.16% Unkown
HY-113638 CVT-11127 99.88% Unkown
HY-155033 SSI-4 Inhibitor 99.95% Unkown
HY-12756 E6446 ≥98.0% Unkown
HY-139077 SCD1 inhibitor-3 Inhibitor 98.55% Unkown
HY-112812 SCD1 inhibitor-1 Inhibitor 99.78% Unkown
HY-102045 T-3764518 Inhibitor 99.86% Unkown
HY-155403 SCD1/5-IN-1 Inhibitor 99.58% Unkown
HY-159098 dWIZ-1 / Unkown
HY-132847 Vibozilimod Agonist 99.52% Unkown
HY-139293 PF-07059013 / Unkown
HY-111315 XEN103 Inhibitor / Unkown
HY-114184 MK-8245 analog Inhibitor / Unkown
HY-118117 Rovatirelin / Unkown
HY-150125 SCD1-IN-1 Inhibitor / Unkown
HY-152775A RK-0133114 Inhibitor / Unkown
HY-159099 HbF inducer 2 / Unkown
HY-161787 G9a-IN-2 Inhibitor / Unkown
HY-E70265 18:0 Coenzyme A triammonium / Unkown
HY-RS12494 SCD Human Pre-designed siRNA Set A / Unkown
HY-RS12495 Scd Rat Pre-designed siRNA Set A / Unkown
HY-RS12496 Scd1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12497 SCD5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-155209 SCD1 inhibitor-5 Inhibitor / Unkown
HY-163820 WIZ degrader 4 / Unkown
HY-163824 WIZ degrader 7 / Unkown
HY-W013627S trans,trans-2,4-Decadienal-d4 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scd NCBI NCBI:6319
Canis familiaris Scd NCBI NCBI:486839
Macaca fascicularis Scd NCBI NCBI:102120948
Mus musculus Scd NCBI
Leporidae Scd NCBI
Macaca mulatta Scd NCBI NCBI:710155