1. Gene
  2. ITGB3 - integrin subunit beta 3 Gene

ITGB3 - integrin subunit beta 3 Gene

Homo sapiens

Also known as GT; GT2; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; BDPLT24

Gene ID: 3690 | Gene type: protein coding

About ITGB3

Cytogenetic location: 17q21.32 Genomic coordinates (GRCh38): 17:47,253,827-47,313,743 (from NCBI)

This gene has 4 transcripts (splice variants), 265 orthologues, 8 paralogues and is associated with 6 phenotypes. Broad expression in thyroid (RPKM 33.0), endometrium (RPKM 10.1) and 14 other tissues.

Summary

The ITGB3 protein product is the Integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

ITGB3 Products(1)

mRNA Protein Name
NM_000212.3 NP_000203.2 integrin beta-3 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to C-X3-C chemokine binding IDA
IDA: Inferred from direct assay
23125415 GOA
enables cell adhesion molecule binding IPI
IPI: Inferred from physical interaction
8837777 GOA
enables enzyme binding IPI
IPI: Inferred from physical interaction
21670307 GOA
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
22505472 GOA
contributes to fibroblast growth factor binding IDA
IDA: Inferred from direct assay
18441324 GOA
enables fibronectin binding IMP
IMP: Inferred from mutant phenotype
24658351 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
11606749 GOA
contributes to insulin-like growth factor I binding IDA
IDA: Inferred from direct assay
19578119 GOA
enables integrin binding IPI
IPI: Inferred from physical interaction
20826760 GOA
contributes to neuregulin binding IDA
IDA: Inferred from direct assay
20682778 GOA
enables protease binding IDA
IDA: Inferred from direct assay
22505472 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
1694173 GOA
enables protein disulfide isomerase activity IDA
IDA: Inferred from direct assay
12204115 GOA
enables vascular endothelial growth factor receptor 2 binding IPI
IPI: Inferred from physical interaction
10022831 GOA
Biological Process GO Annotation Evidence Reference Source
involved in activation of protein kinase activity IMP
IMP: Inferred from mutant phenotype
10022831 GOA
involved in apolipoprotein A-I-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
23726972 GOA
involved in apoptotic cell clearance IGI
IGI: Inferred from genetic interaction
20826760 GOA
involved in cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
12807887 GOA
involved in cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
7525578 GOA
involved in cell-substrate adhesion IMP
IMP: Inferred from mutant phenotype
19933311 GOA
involved in heterotypic cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
20563599 GOA
involved in mesodermal cell differentiation IEP
IEP: Inferred from expression pattern
23154389 GOA
involved in negative chemotaxis IMP
IMP: Inferred from mutant phenotype
23726972 GOA
involved in negative regulation of lipid storage IMP
IMP: Inferred from mutant phenotype
15215180 GOA
involved in negative regulation of lipid transport IMP
IMP: Inferred from mutant phenotype
15215180 GOA
involved in negative regulation of lipoprotein metabolic process IMP
IMP: Inferred from mutant phenotype
15215180 GOA
acts upstream of or within negative regulation of low-density lipoprotein receptor activity IMP
IMP: Inferred from mutant phenotype
15215180 GOA
involved in negative regulation of macrophage derived foam cell differentiation IMP
IMP: Inferred from mutant phenotype
15215180 GOA
involved in platelet activation IMP
IMP: Inferred from mutant phenotype
15466936 GOA
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
15466936 GOA
involved in positive regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
10022831 GOA
involved in positive regulation of endothelial cell proliferation IMP
IMP: Inferred from mutant phenotype
10022831 GOA
involved in positive regulation of peptidyl-tyrosine phosphorylation IMP
IMP: Inferred from mutant phenotype
10022831 GOA
involved in regulation of postsynaptic neurotransmitter receptor internalization EXP
EXP: Inferred from Experiment
18549786 GOA
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
18549786 GOA
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
18549786 GOA
involved in smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
8837777 GOA
involved in substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
24658351 GOA
involved in symbiont entry into host cell IMP
IMP: Inferred from mutant phenotype
25063885 GOA
Cellular Component GO Annotation Evidence Reference Source
part of alphav-beta3 integrin-HMGB1 complex IDA
IDA: Inferred from direct assay
20826760 GOA
part of alphav-beta3 integrin-IGF-1-IGF1R complex IDA
IDA: Inferred from direct assay
19578119 GOA
part of alphav-beta3 integrin-PKCalpha complex IDA
IDA: Inferred from direct assay
16014375 GOA
located in cell surface IDA
IDA: Inferred from direct assay
7525578 GOA
located in cell-cell junction IDA
IDA: Inferred from direct assay
19461049 GOA
located in filopodium membrane IDA
IDA: Inferred from direct assay
25063885 GOA
located in focal adhesion IDA
IDA: Inferred from direct assay
23023225 GOA
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
18549786 GOA
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18549786 GOA
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18549786 GOA
part of integrin alphaIIb-beta3 complex IPI
IPI: Inferred from physical interaction
15378069 GOA
part of integrin alphav-beta3 complex IDA
IDA: Inferred from direct assay
20826760 GOA
part of integrin alphav-beta3 complex IPI
IPI: Inferred from physical interaction
11546839 GOA
part of integrin complex IDA
IDA: Inferred from direct assay
15215180 GOA
located in lamellipodium membrane IDA
IDA: Inferred from direct assay
25063885 GOA
located in melanosome IDA
IDA: Inferred from direct assay
15466936 GOA
located in microvillus membrane IDA
IDA: Inferred from direct assay
25063885 GOA
located in nucleus IDA
IDA: Inferred from direct assay
22027834 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
15466936 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
15344881 GOA
part of receptor complex IDA
IDA: Inferred from direct assay
23382219 GOA
located in ruffle membrane IDA
IDA: Inferred from direct assay
25063885 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ITGB3 Protein Structure

Integrin_beta

Integrin_beta: Integrin beta chain VWA domain (38 - 461)

Integrin_B_tail

Integrin_B_tail: Integrin beta tail domain (634 - 718)

Integrin_b_cyt

Integrin_b_cyt: Integrin beta cytoplasmic domain (742 - 787)

  • 0
  • 200
  • 400
  • 600
  • 788 a.a.
Protein Preferred Names Protein Names

integrin beta-3

antigen CD61

ITGB3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ITGB3 P05106 Tln1 Mus musculus P26039
NMR
21134644
Intra
ITGB3 P05106 Tln1 Mus musculus P26039
NMR
17218263
Intra
ITGB3 P05106 CX3CL1 Homo sapiens P78423
Anti Bait CoIP
23125415
Intra
ITGB3 P05106 ITGA2B Homo sapiens P08514-1
Pull Down
22178926
Intra
ITGB3 P05106 ITGA2B Homo sapiens P08514-1
Pull Down
25849143
Intra
ITGB3 P05106 ITGA2B Homo sapiens P08514-1
SPR
25849143
Intra
ITGB3 P05106 TLN1 Homo sapiens Q9Y490
Affinity Techniques
16546176
Intra
ITGB3 P05106 TLN1 Homo sapiens Q9Y490
FPS
35044719
Intra
ITGB3 P05106 TLN1 Homo sapiens Q9Y490
Saturation Binding
16546176
Intra
ITGB3 P05106 ITGAV Homo sapiens P06756
X-Ray Diffraction
11884718
Intra
ITGB3 P05106 ITGAV Homo sapiens P06756
Pull Down
22178926
Intra
ITGB3 P05106 ITGAV Homo sapiens P06756
Solid Phase Assay
1694173
Intra
ITGB3 P05106 ITGAV Homo sapiens P06756
Anti Bait CoIP
20639902
Intra
ITGB3 P05106 FLNA Homo sapiens P21333
NMR
25849143
Intra
ITGB3 P05106 FLNA Homo sapiens P21333
SPR
25849143
Cross
ITGB3 P05106 Prkd1 Mus musculus Q62101
ELISA
17485491
Intra
ITGB3 P05106 ITGA2B Homo sapiens P08514
TAP
19279667
Intra
ITGB3 P05106 ITGA2B Homo sapiens P08514
Lex-A Dimerization
14681217
Intra
ITGB3 P05106 PTPN1 Homo sapiens P18031
Anti Bait CoIP
16115959
Cross
ITGB3 P05106 ACTN1 Gallus gallus P05094
Solid Phase Assay
2116421
Cross
ITGB3 P05106 polg_wnv West Nile virus P06935
Anti Bait CoIP
16275649
Cross
ITGB3 P05106 polg_wnv West Nile virus P06935
3D-EM
16275649
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ITGB3 Proteins

Cat. No. Product Name Accession Purity
HY-P73868 Integrin alpha V beta 3 Protein, Human (HEK293, His, solution) P06756-1 (F31-V992)&P05106-1 (G27-D718) ≥95%
HY-P77716 Integrin alpha 2B beta 3 Protein, Human (HEK293, His) P08514 (L32-R993)&P05106 (G27-D718) ≥95%
HY-P77719 Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi) P06756-1 (F31-V992)&P05106-1 (G27-D718) ≥95%

Related Diseases

Diseases Alias
Bleeding Disorder, Platelet-Type, 24

BDPLT24

Glanzmann Thrombasthenia-Like With Macrothrombocytopenia 2

Bleeding Disorder, Platelet-Type, 24, Autosomal Dominant

Glanzmann Thrombasthenia 2

GT2

Bleeding Disorder, Platelet-Type, 23

Bdplt23

Glanzmann Thrombasthenia 1

Glanzmann Thrombasthenia

Thrombasthenia Of Glanzmann And Naegeli

Glanzmann'S Thrombasthenia

Bdplt2

Platelet Glycoprotein Iib-Iiia Deficiency

Deficiency Of Platelet Fibrinogen Receptor

GT1

Gt

Platelet Fibrinogen Receptor Deficiency

Glycoprotein Complex Iib-Iiia Deficiency

Deficiency Of Glycoprotein Complex Iib-Iiia

Glycoprotein Iib/Iiia Defect

Glanzmann Thrombasthenia, Type A

Thrombasthenia

Bleeding Disorder, Platelet-Type, 2

Gp Iib-Iiia Complex Deficiency

Deficiency Of Gp Iib-Iiia Complex

Platelet-Type Bleeding Disorder 2

Thrombocytasthenia

Deficiency Of Gp 2b 3a Complex

Diacyclothrombopathia 2b 3a

Glanzmann Thrombasthenia Type A

Platelet Fibrinogen Receptor, Deficiency Of

Platelet Glycoprotein 2b 3a Deficiency

Glanzmann Disease

Glanzmann-Naegeli Disorder

Hereditary Hemorrhagic Thrombasthenia

Hereditary Thrombasthenia

Bleeding Disorder Platelet-Type 2

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Thrombasthenia
Bleeding Disorder, Platelet-Type, 16

Platelet-Type Bleeding Disorder 16

BDPLT16

Glanzmann Thrombasthenia-Like With Macrothrombocytopenia 1

Bleeding Disorder, Platelet-Type, 16, Autosomal Dominant

Autosomal Dominant Glanzmann Thrombasthenia

Autosomal Dominant Thrombasthenia Of Glanzmann And Naegeli

Bleeding Disorder, Platelet Type 16

Glanzmann Thrombasthenia, Autosomal Dominant

Autosomal Dominant Macrothrombocytopenia
Coronary Thrombosis

Coronary Artery Thrombosis

Purpura

Purpuric Disorder

West Nile Virus

West Nile Virus, Susceptibility To

Wnv

Wnv, Susceptibility To

West Nile Viral Infection

Encephalitis, West Nile Fever

West Nile Fever

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Fetal And Neonatal Alloimmune Thrombocytopenia

Nait

Neonatal Alloimmune Thrombocytopenia

Fnait

Heparin-Induced Thrombocytopenia

Hit

Hat

Heparin-Associated Thrombocytopenia

Heparin-Induced Thrombocytopenia Type 2

Sclerosing Liposarcoma
Bernard-Soulier Syndrome

Giant Platelet Syndrome

BSS

Von Willebrand Factor Receptor Deficiency

Bdplt1

Platelet Glycoprotein Ib Deficiency

Bernard-Soulier Syndrome, Type A1

Bernard-Soulier Syndrome, Type B

Bernard Soulier Syndrome

Deficiency Of Platelet Glycoprotein 1b

Hemorrhagiparous Thrombocytic Dystrophy

Bernard-Soulier Syndrome Type C

Bleeding Disorder, Platelet-Type, 1

Glycoprotein Ib, Platelet, Deficiency Of

Giant Platelet Disorder, Isolated

Giant Platelet Disease

Macrothrombocytopenia, Familial Bernard-Soulier Type

Bernard-Soulier Syndrome, Type C

Bernard - Soulier Thrombopathy

Hemorrhagic Dystrophic Thrombocytopenia

Thrombopathy, Bernard-Soulier

Platelet Glycoprotein 1b, Deficiency Of

Hemorrhagioparous Thrombocytic Dystrophy

Bernard-Soulier Syndrome Type A1

Bernard-Soulier Syndrome Type B

Bleeding Disorder Platelet-Type 1

Gpd

Macrothrombocytopenia, Familial, Bernard-Soulier Type

Thrombocytopenic Purpura, Autoimmune

Idiopathic Thrombocytopenic Purpura

Autoimmune Thrombocytopenic Purpura

Immune Thrombocytopenic Purpura

Itp

Idiopathic Purpura

AITP

Ideopath Thrombocytopenic Pur

Primary Thrombocytopenic Purpura

Werlhof'S Disease

Thrombocytopenic Purpura Autoimmune

Purpura Thrombocytopenic Idiopathic

Purpura, Thrombocytopenic, Idiopathic

Autoimmune Thrombocytopenia

Thrombocytopenia Due To Platelet Alloimmunization

Idiopathic Thrombocytopenia

Idiopathic Thrombocytopenia Purpura

Frank'S Essential Thrombocytopenia

Itp - [Idiopathic Thrombocytopenia Purpura]

Werlhof Disease

Primary Autoimmune Thrombocytopenic Purpura

Haemorrhagic Purpura

Essential Thrombocytopenia

Purpura Haemorrhagica

Erythroleukemia
Insulin-Like Growth Factor I

Insulin-Like Growth Factor I Deficiency

IGF1 DEFICIENCY

Insulin-Like Growth Factor I, Resistance To

Growth Retardation With Deafness And Mental Retardation Due To Igf1 Deficiency

Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency

Growth Delay Due To Insulin-Like Growth Factor I Resistance

IGF1RES

Igf-I Resistance

Somatomedin, End-Organ Insensitivity To

Somatomedin-C

Somatomedin-C, Resistance To

Growth Retardation With Sensorineural Deafness And Mental Retardation

Insulin-Like Growth Factor 1 Resistance To

Igf-1 Resistance

Somatomedin End-Organ Insensitivity To

Somatomedin-C Resistance To

Growth Restriction With Sensorineural Deafness And Intellectual Disability

Growth Delay-Deafness-Intellectual Disability Syndrome

Growth Delay-Hearing Loss-Intellectual Disability Syndrome

Igf-1 Deficiency

Primary Insulin-Like Growth Factor Deficiency

Resistance To Igf-1

Insulin-Like Growth Factor 1 Resistance

End-Organ Insensitivity To Somatomedin

Igf1 Resistance

Resistance To Insulin-Like Growth Factor I

Resistance To Somatomedin-C

Insulin-Like Growth Factor 1, Resistance To

Thrombosis

Thrombosis Of Blood Vessel

Polycythemia Vera

PV

Polycythemia Rubra Vera

Prv

Osler-Vaquez Disease

Chronic Erythremia

Polycythaemia Rubra Vera

Primary Polycythemia

Vaquez Disease

Polycythemia Vera, Somatic

Osler-Vaquez Syndrome

Proliferative Polycythaemia

Polycythemia Ruba Vera

Acquired Primary Erythrocytosis

Heilmeyer-Schoner Disease

Vaquez Osler Disease

Primary Polycythaemia

Adenomyosis

Endometriosis Of Uterus

Endometriosis Interna

Endometriosis Of Myometrium

Endometriosis, Myometrium

Uterine Adenomyosis

Adenomyosis Uteri

Internal Endometriosis

Polycythemia

Erythrocythemia

Polycythemia Vera

Polycythaemia Due To High Altitude

Thrombophilia

Hypercoagulability State

Osteopetrosis

Marble Bone Disease

Albers-Schonberg Disease

Osteopetroses

Marble Bones

Osteopetrosis And Related Disorders

Congenital Osteopetrosis

Marble Bone

Albers-Schoenberg Disease

Albers-Schonberg Osteopetrosis

Osteosclerosis Fragilis

Ivory Bones

Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category

Primary Thrombocytopenia
Gastric Teratoma

Teratoma Of Stomach

Placental Insufficiency

Uteroplacental Vascular Insufficiency

Endocarditis
Thrombocytopenia Due To Platelet Alloimmunization

Immune Thrombocytopenia

Autoimmune Thrombocytopenia

Immune Thrombocytopenic Purpura

Itp

Auto-Immune Thrombocytopenia

Thrombocytopenia Due To Immune Destruction

Autoimmune Thrombocytopenic Purpura

Idiopathic Thrombocytopenic Purpura

Werlhof Disease

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Anomaly

Coronary Artery Disease, Susceptibility To

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries

Acquired Thrombocytopenia

Secondary Thrombocytopenia

Bleeding Disorder, Platelet-Type, 18

Platelet-Type Bleeding Disorder 18

BDPLT18

Bleeding Disorder Due To Calcium- And Dag-Regulated Guanine Exchange Factor-1 Deficiency

Bleeding Disorder Due To Caldag-Gefi Deficiency

Bleeding Disorder, Platelet Type 18

Kaposi Sarcoma

Kaposi'S Sarcoma

Kaposi Sarcoma, Susceptibility To

Kaposi'S Sarcoma Of Lung

Kaposi'S Sarcoma Of Palate

Kaposi'S Sarcoma Of Soft Tissue

Kaposi'S Sarcoma-Associated Herpesvirus

Multiple Idiopathic Pigmented Hemangiosarcoma

Multiple Idiopathic Pigmented Hemangiosarcoma, Susceptibility To

African Lymphadenopathic Kaposi'S Sarcoma

Anal Kaposi'S Sarcoma

Cardiac Kaposi'S Sarcoma

Central Nervous System Kaposi'S Sarcoma

Conjunctival Kaposi'S Sarcoma

Corneal Kaposi'S Sarcoma

Cutaneous Kaposi'S Sarcoma

Esophageal Kaposi'S Sarcoma

Gallbladder Kaposi'S Sarcoma

Gastric Kaposi'S Sarcoma

Intestinal Kaposi'S Sarcoma

Kaposi'S Sarcoma Of Anus

Kaposi'S Sarcoma Of Central Nervous System

Kaposi'S Sarcoma Of Conjunctiva

Kaposi'S Sarcoma Of Cornea

Kaposi'S Sarcoma Of Esophagus

Kaposi'S Sarcoma Of Gastrointestinal Sites

Kaposi'S Sarcoma Of Heart

Kaposi'S Sarcoma Of Lymph Nodes

Kaposi'S Sarcoma Of Penis

Kaposi'S Sarcoma Of Skin

Kaposi'S Sarcoma Of Soft Tissues

Kaposi'S Sarcoma Of The Cns

Kaposi'S Sarcoma Of The Gallbladder

Kaposi'S Sarcoma Of The Prostate

Kaposi'S Sarcoma, Lung

Kaposi'S Sarcoma, Skin

Lymph Node Kaposi'S Sarcoma

Lymphadenopathic Kaposi'S Sarcoma

Palate Kaposi'S Sarcoma

Penis Kaposi'S Sarcoma

Prostate Kaposi'S Sarcoma

Pulmonary Kaposi'S Sarcoma

Soft Tissue Kaposi'S Sarcoma

Hhv8

Human Herpesvirus 8

Kshv

Kaposi Sarcoma Herpesvirus

Mediterranean Kaposi Sarcoma

Non Aids Related Kaposi Sarcoma

Sarcoma, Kaposi

Sarcoma, Kaposi, Susceptibility To

Non-Aids-Related Kaposi Sarcoma

Angiolymphoid Hyperplasia

Angiofollicular Ganglionic Hyperplasia

Multi-Centric Castleman'S Disease

Arteriosclerosis

Arteriosclerotic Vascular Disease

Malignant Gastric Germ Cell Tumor

Germ Cell Tumor Of The Stomach

Germ Cell Tumour Of The Stomach

Malignant Gastric Germ Cell Tumour

Myelitis

Spinal Cord Inflammation Nos

Radiculomyelitis Nos

Myeloradiculitis

Myeloproliferative Neoplasm

Myeloproliferative Disorder

Chronic Myeloproliferative Disease

Myeloproliferative Neoplasms

Chronic Myeloproliferative Disorder

Cmpd

Cmpd, U

Chronic Myeloproliferative Disorders

Mpd

Mpn

Myeloproliferative Disorders

Myeloproliferative Disease

Campomelic Dysplasia

Blood Coagulation Disease

Blood Coagulation Disorders

Coagulation Protein Disease

Inherited Blood Coagulation Disease

Postpartum Coagulation Defect

Postpartum Coagulation Defect With Delivery

Coagulation Protein Disorders

Puerperal Coagulopathy

Myeloproliferative Syndrome, Transient

Transient Abnormal Myelopoiesis

Transient Myeloproliferative Syndrome

Transient Myeloproliferative Disease

Mst

Tam

Leukemia, Transient, Of Down Syndrome

Tmd

Leukemia, Transient

Transient Leukemia

Transient Leukemia Of Down Syndrome

Blood Platelet Disease

Platelet Disorder

Blood Platelet Disorders

Thrombocytopathy

Platelet Dysfunction

Platelet Disorders

Qualitative Platelet Deficiency

Focal Segmental Glomerulosclerosis

Familial Idiopathic Steroid-Resistant Nephrotic Syndrome

Focal Glomerulosclerosis

Fsgs

Segmental Glomerulosclerosis

Glomerulosclerosis, Focal Segmental

Fgs

Focal Glomerular Sclerosis

Familial Idiopathic Nephrotic Syndrome

Focal Sclerosis With Hyalinosis

Glomerulosclerosis, Focal

Glomerulosclerosis Focal

Glomerulosclerosis, Segmental, Focal

Focal Segmental Glomerulosclerosis, Not Otherwise Specified

Infertility
Acute Megakaryocytic Leukemia

Acute Megakaryoblastic Leukemia

Acute Megakaryoblastic Leukaemia

Megakaryocytic Myelosis

Thrombocytic Leukaemia

Amkl

Aml M7

Acute Myeloblastic Leukemia Type 7

Acute Myeloid Leukemia M7

Megakaryoblastic Leukemia Acute

Leukemia, Megakaryoblastic, Acute

Acute Myeloid Leukaemia, M7

Acute Megakaryocytic Leukaemia

Acute Megakaryoblastic Leukaemia, Fab M7

Fab M7

Malignant Megakaryocytosis

M7 - Acute Megakaryoblastic Leukaemia

Megakaryoblastic Leukaemia

Megakaryocytic Leukaemia

Acute Megakaryoblastic Leukaemia, Nos

Acute Megakaryoblastic Leukaemia Without Mention Of Remission

Fallopian Tube Clear Cell Adenocarcinoma

Clear Cell Carcinoma Of The Fallopian Tube

Marfan Syndrome

MFS

Mfs1

Marfan'S Syndrome

Marfan Syndrome Type 1

Marfan Syndrome, Type I

Mass Phenotype

Contractural Arachnodactyly

Mass Syndrome

Octd

Overlap Connective Tissue Disease

Marfanoid Hypermobility Syndrome

Marfan Disease

Ciliary Dyskinesia, Primary, 1

CILD1

Pcd

Primary Ciliary Dyskinesia 1

Kartagener Syndrome

Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

Immotile Cilia Syndrome

Ics

Polynesian Bronchiectasis

Primary Ciliary Dyskinesia 1 With Or Without Situs Inversus

Ics1

Immotile Cilia Syndrome 1

Primary Ciliary Dyskinesia

KTGS

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome Kartagener Type

Primary Ciliary Dyskinesia Kartagener Type

Siewert Syndrome

Immotile Cilia

Dyskinesia, Ciliary, Primary, Type 1

Ciliary Motility Disorders

Mucocele Of Appendix

Appendicele Mucocele

Appendicular Mucocele

Appendiceal Mucocele

Arrhythmogenic Right Ventricular Cardiomyopathy

Arrhythmogenic Right Ventricular Dysplasia

Arvc

Arvd

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

Arvc Cardiomyopathy

Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia

Arvd/C

Right Ventricular Dysplasia, Arrhythmogenic

Ventricular Dysplasia, Right, Arrhythmogenic

Cardiomyopathy, Ventricular, Right, Arrhythmogenic

Dysplasia, Arrhythmogenic Right Ventricular

Osteoporosis

Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

Bone Mineral Density Quantitative Trait Locus

Bmnd

Osteoporosis, Involutional

Osteoporosis, Susceptibility To

Osteoporosis, Postmenopausal, Susceptibility

Bone Mineral Density Variation Qtl, Osteoporosis

OSTEOP

Involutional Osteoporosis

Senile Osteoporosis

Osteoporosis Postmenopausal

Bone Mineral Density, Quantitative Trait Locus

Osteoporosis, Senile

Idiopathic Osteoporosis

Bone Rarefaction Nos

Type 1 Osteoporosis

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Essential Thrombocythemia

Essential Thrombocytosis

Familial Thrombocytosis

Hemorrhagic Thrombocythemia

Hereditary Thrombocythemia

Primary Thrombocytosis

Idiopathic Thrombocythemia

Primary Thrombocythemia

Thrombocythemia, Essential

Essential Thrombocythaemia

Et

Familial Thrombocythemia

Thrombocythemia Essential

Cerebral Palsy

Infantile Cerebral Palsy

Mixed Cerebral Palsy

Palsy Cerebral

Palsy, Cerebral

Cerebral Palsy, Mixed

Appendix Lymphoma

Appendiceal Lymphoma

Leukemia, Chronic Myeloid

Chronic Myeloid Leukemia

Chronic Myelogenous Leukemia

CML

Chronic Granulocytic Leukemia

Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

Chronic Myeloid Leukaemia

Chronic Granulocytic Leukaemia

Chronic Myelogenous Leukaemia

Myeloid Leukemia, Chronic

Leukemia, Chronic Myelogenous

Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

Cml - Chronic Myelogenous Leukemia

Cgl

Chronic Myelocytic Leukemia

Leukemia, Chronic Myeloid, Atypical

ACML

Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

Myeloid Leukemia Chronic

Leukemia, Myeloid, Chronic

Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

Cml- [Chronic Myeloid Leukaemia]

Cgl - [Chronic Granulocytic Leukaemia]

Chronic Myelocytic Leukaemia

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus ITGB3 MGD MGI:96612
Rattus norvegicus ITGB3 RGD RGD:628868
Macaca mulatta ITGB3 VGNC VGNC:104624
Macaca fascicularis ITGB3 NCBI NCBI:102117791