DNAJB13 - DnaJ heat shock protein family (Hsp40) member B13 Gene

Homo sapiens (human)

Also known as CILD34; TSARG5; TSARG6; RSPH16A

Gene ID: 374407 | Gene type: protein coding

About DNAJB13

Summary

This gene encodes a member of the heat shock protein 40 co-chaperone family which is produced in large amounts in the testis and is located on the radial spokes of the axoneme in human sperm flagella and Other flagellar structures. The encoded protein associates with the sperm annulus, as part of the septin complex, through direct interaction with septin 4, during sperm terminal differentiation. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and male infertility. [provided by RefSeq, Apr 2017]

DNAJB13 Products(1)

mRNA	Protein	Name
XM_024448508.2	XP_024304276.1	dnaJ homolog subfamily B member 13 isoform X4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21994455	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in axonemal central apparatus assembly	IMP IMP: Inferred from mutant phenotype	27486783	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in motile cilium	IDA IDA: Inferred from direct assay	27486783	GOA
located in sperm flagellum	IDA IDA: Inferred from direct assay	27486783	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dnaJ homolog subfamily B member 13

DnaJ (Hsp40) homolog, subfamily B, member 13	DnaJ (Hsp40) related, subfamily B, member 13
DnaJ-like protein	radial spoke 16 homolog A
testis and spermatogenesis cell-related protein 6	testis spermatocyte apoptosis-related gene 6 protein
testis sperm

DNAJB13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	DNAJB13	P59910	MSS51	Homo sapiens	Q4VC12	Validated Y2H	32296183
Intra	DNAJB13	P59910	MSS51	Homo sapiens	Q4VC12	Y2H Array	32296183
Intra	DNAJB13	P59910	MSS51	Homo sapiens	Q4VC12	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	RAB3IP	Homo sapiens	Q96QF0-7	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	RAB3IP	Homo sapiens	Q96QF0-7	Validated Y2H	32296183
Intra	DNAJB13	P59910	RAB3IP	Homo sapiens	Q96QF0-7	Y2H Array	32296183
Intra	DNAJB13	P59910	TOM1L1	Homo sapiens	O75674-2	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	TOM1L1	Homo sapiens	O75674-2	Y2H Array	32296183
Intra	DNAJB13	P59910	PIBF1	Homo sapiens	Q4G0R1	Validated Y2H	32296183
Intra	DNAJB13	P59910	PIBF1	Homo sapiens	Q4G0R1	Y2H Array	32296183
Intra	DNAJB13	P59910	PIBF1	Homo sapiens	Q4G0R1	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	LHX4	Homo sapiens	Q969G2	Validated Y2H	32296183
Intra	DNAJB13	P59910	LHX4	Homo sapiens	Q969G2	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	LHX4	Homo sapiens	Q969G2	Y2H Array	32296183
Intra	DNAJB13	P59910	ZRANB1	Homo sapiens	Q9UGI0	Validated Y2H	32296183
Intra	DNAJB13	P59910	ZRANB1	Homo sapiens	Q9UGI0	Y2H Array	32296183
Intra	DNAJB13	P59910	ZRANB1	Homo sapiens	Q9UGI0	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	SEPTIN1	Homo sapiens	Q8WYJ6	Validated Y2H	32296183
Intra	DNAJB13	P59910	MDFI	Homo sapiens	Q99750	Validated Y2H	32296183
Intra	DNAJB13	P59910	MDFI	Homo sapiens	Q99750	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	MDFI	Homo sapiens	Q99750	Y2H Array	32296183
Intra	DNAJB13	P59910	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	32296183
Intra	DNAJB13	P59910	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
Intra	DNAJB13	P59910	PLK4	Homo sapiens	O00444	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	PLK4	Homo sapiens	O00444	Y2H Array	32296183
Intra	DNAJB13	P59910	ZC3H12A	Homo sapiens	Q5D1E8	Validated Y2H	32296183
Intra	DNAJB13	P59910	ZC3H12A	Homo sapiens	Q5D1E8	Y2H Array	32296183
Intra	DNAJB13	P59910	ZC3H12A	Homo sapiens	Q5D1E8	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	DNAJB13	P59910	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	DNAJB13	P59910	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Cross	DNAJB13	P59910	PB2	Influenza A virus	B4URF7	Pull Down	21994455
Cross	DNAJB13	P59910	PB2	Influenza A virus	B4URF7	BiFC	21994455

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03861	DNAJB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03862	Dnajb1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03863	Dnajb1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03864	DNAJB11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03865	DNAJB12 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03876	DNAJC13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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