2. Gene
  3. Sstr2 - somatostatin receptor 2 Gene

Sstr2 - somatostatin receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Smstr2

Gene ID: 54305 | Gene type: protein coding

About Sstr2

Primary_assembly 10: 98,664,216-98,674,351 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 264 orthologues, 14 paralogues and is associated with 7 phenotypes. Biased expression in Adrenal (RPKM 48.4), Brain (RPKM 31.2) and 3 other tissues.

Summary

Enables PDZ domain binding activity and Somatostatin Receptor activity. Involved in several processes, including brain development; cellular response to lipid; and peristalsis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR2 (Somatostatin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sstr2 Products(1)

mRNA Protein Name
NM_019348.2 NP_062221.1 somatostatin receptor type 2

Sstr2 Protein Structure

7tmA_SSTR2

7tmA_SSTR2: cd15971 (43 - 322)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (44 - 70)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (77 - 103)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (114 - 144)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (156 - 178)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (204 - 233)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (248 - 278)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (290 - 315)

  • 0
  • 100
  • 200
  • 300
  • 369 a.a.
Protein Preferred Names Protein Names

somatostatin receptor type 2

SRIF-1

SS-2-R

SS2-R

SS2R

somatostatin receptor subtype 2

somatotropin release-inhibiting factor receptor

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0036 Octreotide Agonist 99.64% Unkown
HY-P0036B Octreotide pamoate Agonist / Unkown
Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-P0024 Veldoreotide Activator / Phase 2
HY-P5362 NODAGA-LM3 Antagonist 99.33% Phase 2
HY-P5362A NODAGA-LM3 TFA Antagonist / Phase 2
HY-P3294 Onzigolide Agonist / Phase 2
HY-106103 Seglitide Agonist / Phase 2
HY-P10137 Satoreotide Antagonist / Phase 2
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1932 Cortistatin-14 99.96% Unkown
HY-P1202A CYN 154806 TFA Antagonist 99.81% Unkown
HY-P1202 CYN 154806 Antagonist 99.76% Unkown
HY-P3124A BIM-23190 hydrochloride Agonist 99.64% Unkown
HY-P4452 PRL 2915 Antagonist 99.57% Unkown
HY-P3618 Cortistatin-29 (reduced) 99.22% Unkown
HY-P0024A Veldoreotide TFA Agonist 98.37% Unkown
HY-P4469 PRL 3195 Antagonist / Unkown
HY-P2545 [Tyr1]-Somatostatin-14 / Unkown
HY-110161 sst2 Receptor agonist-1 Agonist / Unkown
HY-P3124 BIM-23190 Agonist / Unkown
HY-P2434 AP102 / Unkown
HY-P2150 Cortistatin-29 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sstr2 NCBI NCBI:6752