2. Gene
  3. SLAMF7 - SLAM family member 7 Gene

SLAMF7 - SLAM family member 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 19A; CS1; CD319; CRACC

Gene ID: 57823 | Gene type: protein coding

About SLAMF7

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:160,739,057-160,754,821 (from NCBI)

This gene has 11 transcripts (splice variants), 138 orthologues and 9 paralogues. Biased expression in lymph node (RPKM 22.3), appendix (RPKM 19.3) and 13 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in adaptive immune response. Predicted to act upstream of or within regulation of natural killer cell activation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

SLAMF7 Products(10)

mRNA Protein Name
NM_001282588.2 NP_001269517.1 SLAM family member 7 isoform b precursor
NM_001282589.2 NP_001269518.1 SLAM family member 7 isoform c precursor
NM_001282590.2 NP_001269519.1 SLAM family member 7 isoform d
NM_001282591.2 NP_001269520.1 SLAM family member 7 isoform e
NM_001282592.2 NP_001269521.1 SLAM family member 7 isoform f precursor
NM_001282593.2 NP_001269522.1 SLAM family member 7 isoform g
NM_001282594.2 NP_001269523.1 SLAM family member 7 isoform h
NM_001282595.1 NP_001269524.1 SLAM family member 7 isoform i
NM_001282596.2 NP_001269525.1 SLAM family member 7 isoform j
NM_021181.5 NP_067004.3 SLAM family member 7 isoform a precursor

SLAMF7 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (23 - 124)

Ig_3

Ig_3: Immunoglobulin domain (130 - 199)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

SLAM family member 7

19A24 protein

Recombinant SLAMF7 Proteins

Cat. No. Product Name Accession Purity
HY-P72416 CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His-Avi) Q9NQ25-1 (S23-M226) ≥95%
HY-P72460 CRACC/SLAMF7 Protein, Human (HEK293, His) Q9NQ25-1 (S23-M226) ≥95%
HY-P77202 CRACC/SLAMF7 Protein, Human (HEK293, hFc) Q9NQ25-1 (S23-M226) ≥95%
HY-P77203 CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, Fc) Q9NQ25-1 (S23-M226) ≥95%
HY-P77205 CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His) Q9NQ25-1 (S23-M226) ≥95%
HY-P78517 CRACC/SLAMF7 Protein, Human (HEK293, mFc) Q9NQ25-1 (S23-M226) ≥95%
HY-P78518 CRACC/SLAMF7 Protein, Human (HEK293, His-Avi) Q9NQ25-1 (S23-M226) ≥95%

Related Diseases

Diseases Alias
Plasmablastic Lymphoma

Pbl

Immunoblastic Large-Cell Lymphoma
Smoldering Myeloma
Lupus Erythematosus

Lupus

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus, Systemic

Subacute Cutaneous Lupus

Le - [Lupus Erythematosus]
Intellectual Developmental Disorder, Autosomal Dominant 10

MRD10

Mental Retardation, Autosomal Dominant 10

Autosomal Dominant Non-Syndromic Intellectual Disability 10

Autosomal Dominant Intellectual Developmental Disorder 10

Autosomal Dominant Mental Retardation 10

Mental Retardation, Autosomal Dominant, Type 10
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Monoclonal Gammopathy Of Uncertain Significance

Monoclonal Gammopathy Of Undetermined Significance

Mgus

Mgus - [Monoclonal Gammopathy Of Undetermined Significance]

Monoclonal Gammopathy Nos

Iga Gammopathy

Monoclonal Gammoglobulinopathy
Igg4-Related Disease

Multifocal Fibrosclerosis

Igg4-Related Sclerosing Disease

Igg4-Related Systemic Disease

Immunoglobulin G4-Related Sclerosing Disease

Hyper-Igg4 Disease

Igg4-Associated Disease

Igg4-Positive Multiorgan Lymphoproliferative Syndrome

Igg4-Related Autoimmune Disease

Igg4-Related Systemic Sclerosing Disease

Igg4-Syndrome

Multifocal Idiopathic Fibrosclerosis

Systemic Igg4-Related Plasmacytic Syndrome

Systemic Igg4-Related Sclerosing Syndrome

Mediastinal Fibrosis, Familial

Retroperitoneal Fibrosis, Familial

Igg4-Rd
Non-Secretory Myeloma
Blood Protein Disease

Blood Protein Disorders

Blood Protein Disorder
Plasma Cell Leukemia

Plasma Cell Leukaemia

Leukemia, Plasma Cell

Plasmacytic Leukaemia

Plasmacytic Leukemia

Pcl

Plasma Cell Leukaemia, Nos

Leukemic Plasma Cell

Plasma Cell Leukaemia Without Mention Of Remission
Bone Marrow Cancer

Malignant Neoplasm Of Bone Marrow

Bone Marrow Neoplasm

Bone Marrow Tumor

Malignant Bone Marrow Tumor

Myeloproliferative Disorders

Bone Marrow Neoplasms

Myeloproliferative Disease

Chronic Myeloproliferative Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99454 Azintuxizumab vedotin / Phase 1
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12981 SLAMF7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99453 Azintuxizumab ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLAMF7 VGNC VGNC:34655
Canis familiaris SLAMF7 VGNC VGNC:46208
Mus musculus SLAMF7 MGD MGI:1922595
Macaca mulatta SLAMF7 VGNC VGNC:77547
Rattus norvegicus SLAMF7 RGD RGD:1560190
Felis catus SLAMF7 VGNC VGNC:107940
Others SLAMF7 NCBI