2. Gene
  3. RBM3 - RNA binding motif protein 3 Gene

RBM3 - RNA binding motif protein 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RNPL; IS1-RNPL

Gene ID: 5935 | Gene type: protein coding

About RBM3

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:48,574,484-48,581,162 (from NCBI)

This gene has 11 transcripts (splice variants), 168 orthologues and 36 paralogues. Ubiquitous expression in bone marrow (RPKM 49.3), fat (RPKM 41.3) and 25 other tissues.

Summary

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]

RBM3 Products(1)

mRNA Protein Name
NM_006743.5 NP_006734.1 RNA-binding protein 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15518812 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBM3 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (8 - 78)

  • 0
  • 100
  • 157 a.a.
Protein Preferred Names Protein Names

RNA-binding protein 3

RNA binding motif (RNP1, RRM) protein 3

RBM3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Y2H Prey Pooling
32296183
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Validated Y2H
32296183
Intra RBM3 P98179 CHTOP Homo sapiens Q9Y3Y2-3
Y2H Array
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Validated Y2H
32296183
Intra RBM3 P98179 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3-2
Y2H Array
32296183
Intra RBM3 P98179 PRR3 Homo sapiens P79522
Y2H Array
32296183
Intra RBM3 P98179 PRR3 Homo sapiens P79522
Y2H Prey Pooling
32296183
Intra RBM3 P98179 MYPOP Homo sapiens Q86VE0
Validated Y2H
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Validated Y2H
25416956
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Y2H Prey Pooling
25416956
Intra RBM3 P98179 HNRNPK Homo sapiens P61978
Anti Tag CoIP
35271311
Intra RBM3 P98179 SRSF3 Homo sapiens P84103
Y2H Prey Pooling
32296183
Intra RBM3 P98179 SRSF3 Homo sapiens P84103
Y2H Array
32296183
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Prey Pooling
32296183
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Array
31515488
Intra RBM3 P98179 SNRPA Homo sapiens P09012
Y2H Array
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
Intra RBM3 P98179 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
25416956
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Validated Y2H
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
25416956
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Prey Pooling
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
32296183
Intra RBM3 P98179 KHDRBS2 Homo sapiens Q5VWX1
Y2H Array
31515488
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Array
25416956
Intra RBM3 P98179 RBMX Homo sapiens P38159
Y2H Array
32296183
Intra RBM3 P98179 RBMX Homo sapiens P38159
Validated Y2H
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Validated Y2H
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Y2H Prey Pooling
25416956
Intra RBM3 P98179 RBMY1A1 Homo sapiens P0DJD3
Y2H Array
25416956
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Validated Y2H
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Array
25416956
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Array
32296183
Intra RBM3 P98179 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
25416956
Intra RBM3 P98179 PCBP1 Homo sapiens Q15365
Validated Y2H
32296183
Cross RBM3 P98179 OPG127 Vaccinia virus P68318
Pull Down
15518812
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Testicular Malignant Germ Cell Cancer

Malignant Germ Cell Tumor Of Testis
Periampullary Adenocarcinoma
Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis

Testicular Germ Cell Tumor

Testicular Germ Cell Neoplasm

Testicular Malignant Germ Cell Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11747 RBM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11762 RBMS3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RBM3 VGNC VGNC:54837
Mus musculus RBM3 MGD MGI:1099460
Bos taurus RBM3 VGNC VGNC:52813
Rattus norvegicus RBM3 RGD RGD:620145
Others RBM3 NCBI