2. Gene
  3. RPL9 - ribosomal protein L9 Gene

RPL9 - ribosomal protein L9 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as L9; NPC-A-16

Gene ID: 6133 | Gene type: protein coding

About RPL9

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:39,454,124-39,458,922 (from NCBI)

This gene has 15 transcripts (splice variants) and 172 orthologues. Ubiquitous expression in ovary (RPKM 1269.0), bone marrow (RPKM 646.0) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

RPL9 Products(2)

mRNA Protein Name
NM_000661.5 NP_000652.2 60S ribosomal protein L9
NM_001024921.4 NP_001020092.1 60S ribosomal protein L9
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
Cellular Component GO Annotation Evidence Reference Source
part of cytosolic large ribosomal subunit IDA
IDA: Inferred from direct assay
32669547 GOA
part of cytosolic large ribosomal subunit IPI
IPI: Inferred from physical interaction
25901680 GOA
located in cytosolic ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPL9 Protein Structure

Ribosomal_L6

Ribosomal_L6: Ribosomal protein L6 (12 - 87)

Ribosomal_L6

Ribosomal_L6: Ribosomal protein L6 (99 - 178)

  • 0
  • 100
  • 192 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L9

large ribosomal subunit protein uL6

RPL9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
RPL9 P32969 BICDL2 Homo sapiens A1A5D9
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 BICDL2 Homo sapiens A1A5D9
Y2H Array
32296183
Intra
RPL9 P32969 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
Intra
RPL9 P32969 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 ZBTB14 Homo sapiens O43829
Validated Y2H
25416956
Intra
RPL9 P32969 ZBTB14 Homo sapiens O43829
Y2H Array
25416956
Intra
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Validated Y2H
32296183
Intra
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Y2H Array
32296183
Intra
RPL9 P32969 CCDC184 Homo sapiens Q52MB2
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Y2H Array
32296183
Intra
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Validated Y2H
32296183
Intra
RPL9 P32969 SREK1IP1 Homo sapiens Q8N9Q2
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 PSTPIP1 Homo sapiens O43586
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 PSTPIP1 Homo sapiens O43586
Y2H Array
32296183
Intra
RPL9 P32969 CTNNA3 Homo sapiens Q9UI47-2
Validated Y2H
32296183
Intra
RPL9 P32969 CTTN Homo sapiens Q14247-3
Y2H Array
32296183
Intra
RPL9 P32969 CTTN Homo sapiens Q14247-3
Validated Y2H
32296183
Intra
RPL9 P32969 CTTN Homo sapiens Q14247-3
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
Intra
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
Intra
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Y2H Array
32296183
Intra
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 HMBOX1 Homo sapiens Q6NT76
Validated Y2H
32296183
Intra
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Validated Y2H
25416956
Intra
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Validated Y2H
32296183
Intra
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Array
32296183
Intra
RPL9 P32969 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 VCP Homo sapiens P55072
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 VCP Homo sapiens P55072
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 VCP Homo sapiens P55072
Validated Y2H
32296183
Intra
RPL9 P32969 VCP Homo sapiens P55072
Validated Y2H
25416956
Intra
RPL9 P32969 VCP Homo sapiens P55072
Y2H Array
32296183
Intra
RPL9 P32969 VCP Homo sapiens P55072
Y2H Array
25416956
Intra
RPL9 P32969 SNRPF Homo sapiens P62306
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 SNRPF Homo sapiens P62306
Y2H Array
32296183
Intra
RPL9 P32969 SNRPF Homo sapiens P62306
Validated Y2H
32296183
Intra
RPL9 P32969 SRSF3 Homo sapiens P84103
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 SRSF3 Homo sapiens P84103
Y2H Array
32296183
Intra
RPL9 P32969 SRSF3 Homo sapiens P84103
Validated Y2H
32296183
Intra
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Y2H Array
32296183
Intra
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 PPP1R27 Homo sapiens Q86WC6
Validated Y2H
32296183
Intra
RPL9 P32969 DRAP1 Homo sapiens Q14919
Validated Y2H
32296183
Intra
RPL9 P32969 DRAP1 Homo sapiens Q14919
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 DRAP1 Homo sapiens Q14919
Y2H Array
32296183
Intra
RPL9 P32969 KXD1 Homo sapiens Q9BQD3
Validated Y2H
25416956
Intra
RPL9 P32969 ZBTB7B Homo sapiens O15156
Validated Y2H
25416956
Intra
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 TIFA Homo sapiens Q96CG3
Validated Y2H
25416956
Intra
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 TIFA Homo sapiens Q96CG3
Validated Y2H
32296183
Intra
RPL9 P32969 TIFA Homo sapiens Q96CG3
Y2H Array
32296183
Intra
RPL9 P32969 TRIM37 Homo sapiens O94972
Validated Y2H
25416956
Intra
RPL9 P32969 TRIM37 Homo sapiens O94972
Y2H Array
25416956
Intra
RPL9 P32969 TRIM37 Homo sapiens O94972
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 CBY2 Homo sapiens Q8NA61
Y2H Array
25416956
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Array
32296183
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Anti Tag CoIP
33961781
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Anti Tag CoIP
28514442
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 DHPS Homo sapiens P49366
Validated Y2H
32296183
Intra
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
32296183
Intra
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Validated Y2H
32296183
Intra
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
Intra
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Anti Tag CoIP
33961781
Intra
RPL9 P32969 CEP76 Homo sapiens Q8TAP6
Anti Tag CoIP
28514442
Intra
RPL9 P32969 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Y2H Array
32296183
Intra
RPL9 P32969 STAC3 Homo sapiens Q96MF2
Validated Y2H
32296183
Intra
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Validated Y2H
32296183
Intra
RPL9 P32969 TNFAIP8L1 Homo sapiens Q8WVP5
Y2H Array
32296183
Intra
RPL9 P32969 RALY Homo sapiens Q53GL6
Y2H Prey Pooling
32296183
Intra
RPL9 P32969 RALY Homo sapiens Q53GL6
Validated Y2H
32296183
Intra
RPL9 P32969 RALY Homo sapiens Q53GL6
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Diamond-Blackfan Anemia 6

DBA6

Aase-Smith Syndrome Ii

Aase Syndrome

Aase Smith Syndrome 2

Rpl5-Related Diamond-Blackfan Anemia

Anemia, Diamond-Blackfan, Type 6

Diamond-Blackfan Anemia 1
Diamond-Blackfan Anemia 2

DBA2

Anemia, Diamond-Blackfan, 2

Anemia Diamond-Blackfan 2
Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12206 RPL9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RPL9 RGD RGD:62049
Mus musculus RPL9 MGD MGI:1298373
Felis catus RPL9 VGNC VGNC:79993
Macaca mulatta RPL9 VGNC VGNC:107196
Canis familiaris RPL9 VGNC VGNC:53205