TCF19 - transcription factor 19 Gene

Homo sapiens

Also known as SC1; TCF-19

Gene ID: 6941 | Gene type: protein coding

About TCF19

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,158,589-31,164,215 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele and 189 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), appendix (RPKM 5.7) and 25 other tissues.

Summary

This gene encodes a protein that contains a PHD-type zinc finger domain and likely functions as a transcription factor. The encoded protein plays a role proliferation and Apoptosis of pancreatic beta cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

TCF19 Products(3)

mRNA	Protein	Name
NM_001077511.2	NP_001070979.1	transcription factor 19
NM_001318908.2	NP_001305837.1	transcription factor 19
NM_007109.3	NP_009040.2	transcription factor 19

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21516116	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TCF19 Protein Structure

FHA

PHD

0
100
200
300
345 a.a.

Protein Preferred Names

Protein Names

transcription factor 19

transcription factor SC1

Related Diseases

Diseases

Alias

Psoriasis 8

PSORS8	Psoriasis Susceptibility 8
Psoriasis 8, Susceptibility To

Psoriasis 9

PSORS9	Psoriasis 9, Susceptibility To
Psoriasis Susceptibility 9

Psoriasis 7

PSORS7	Psoriasis 7, Susceptibility To
Psoriasis Susceptibility 7	Psoriasis
Psoriasis Vulgaris	Pv

Peeling Skin Syndrome

Deciduous Skin	Familial Continuous Skin Peeling Syndrome
Idiopathic Deciduous Skin	Keratosis Exfoliativa Congenita
Pss	Peeling Skin Disease
Skin Peeling Syndrome	Familial Continuous Skin Peeling
Keratolysis Exfoliativa Congenita	Exfoliation Syndrome
Keratolysis Exfoliativa

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14301	TCF19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TCF19	RGD	RGD:1302974
Macaca mulatta	TCF19	VGNC	VGNC:83493
Felis catus	TCF19	VGNC	VGNC:66022
Canis familiaris	TCF19	VGNC	VGNC:47191
Bos taurus	TCF19	VGNC	VGNC:35688
Mus musculus	TCF19	MGD	MGI:103180

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