2. Gene
  3. NFKBID - NFKB inhibitor delta Gene

NFKBID - NFKB inhibitor delta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as IkBNS; TA-NFKBH; IkappaBNS

Gene ID: 84807 | Gene type: protein coding

About NFKBID

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,887,952-35,902,303 (from NCBI)

This gene has 11 transcripts (splice variants), 195 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 9.7), appendix (RPKM 2.8) and 19 other tissues.

Summary

Predicted to enable NF-kappaB binding activity. Predicted to be involved in T cell receptor signaling pathway; positive regulation of T-helper 17 cell differentiation; and regulation of gene expression. Predicted to act upstream of or within several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell differentiation in thymus; and positive regulation of thymocyte apoptotic process. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NFKBID Products(5)

mRNA Protein Name
NM_001321831.2 NP_001308760.1 NF-kappa-B inhibitor delta isoform 2
NM_001365705.1 NP_001352634.1 NF-kappa-B inhibitor delta isoform 1
NM_001365706.2 NP_001352635.1 NF-kappa-B inhibitor delta isoform 4
NM_032721.3 NP_116110.2 NF-kappa-B inhibitor delta isoform 3
NM_139239.3 NP_640332.1 NF-kappa-B inhibitor delta isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NFKBID Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (79 - 147)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (183 - 278)

  • 0
  • 100
  • 200
  • 313 a.a.
Protein Preferred Names Protein Names

NF-kappa-B inhibitor delta

I-kappa-B-delta

NFKBID Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra NFKBID Q8NI38 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra NFKBID Q8NI38 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Array
32296183
Intra NFKBID Q8NI38 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 CCHCR1 Homo sapiens Q8TD31-3
Validated Y2H
32296183
Intra NFKBID Q8NI38 TEKT5 Homo sapiens Q96M29
Validated Y2H
32296183
Intra NFKBID Q8NI38 SS18 Homo sapiens Q4VAX2
Validated Y2H
25416956
Intra NFKBID Q8NI38 LGALS14 Homo sapiens Q8TCE9
Validated Y2H
32296183
Intra NFKBID Q8NI38 CTRC Homo sapiens Q99895
Validated Y2H
32296183
Intra NFKBID Q8NI38 MYEF2 Homo sapiens Q9P2K5-2
Validated Y2H
32296183
Intra NFKBID Q8NI38 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra NFKBID Q8NI38 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 PATZ1 Homo sapiens Q9HBE1-4
Validated Y2H
32296183
Intra NFKBID Q8NI38 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra NFKBID Q8NI38 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra NFKBID Q8NI38 TRIML2 Homo sapiens Q8N7C3
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 TRIML2 Homo sapiens Q8N7C3
Y2H Array
32296183
Intra NFKBID Q8NI38 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra NFKBID Q8NI38 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra NFKBID Q8NI38 LMO3 Homo sapiens Q8TAP4-4
Validated Y2H
32296183
Intra NFKBID Q8NI38 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra NFKBID Q8NI38 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 SAMD4A Homo sapiens Q9UPU9-3
Validated Y2H
32296183
Intra NFKBID Q8NI38 RUNX1 Homo sapiens Q01196-8
Y2H Array
32296183
Intra NFKBID Q8NI38 RUNX1 Homo sapiens Q01196-8
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 FAAP20 Homo sapiens Q6NZ36-4
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 FAAP20 Homo sapiens Q6NZ36-4
Y2H Array
32296183
Intra NFKBID Q8NI38 SPMIP2 Homo sapiens Q96LM5
Validated Y2H
32296183
Intra NFKBID Q8NI38 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra NFKBID Q8NI38 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra NFKBID Q8NI38 POMC Homo sapiens P01189
Y2H Array
32296183
Intra NFKBID Q8NI38 POMC Homo sapiens P01189
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 ESR2 Homo sapiens Q92731-3
Validated Y2H
32296183
Intra NFKBID Q8NI38 ZC2HC1B Homo sapiens Q5TFG8
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 ZC2HC1B Homo sapiens Q5TFG8
Y2H Array
32296183
Intra NFKBID Q8NI38 GRB10 Homo sapiens Q13322-4
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 GRB10 Homo sapiens Q13322-4
Y2H Array
32296183
Intra NFKBID Q8NI38 NDUFB7 Homo sapiens P17568
Y2H Array
32296183
Intra NFKBID Q8NI38 NDUFB7 Homo sapiens P17568
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 NICN1 Homo sapiens Q9BSH3
Y2H Array
32296183
Intra NFKBID Q8NI38 NICN1 Homo sapiens Q9BSH3
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 NICN1 Homo sapiens Q9BSH3
Validated Y2H
32296183
Intra NFKBID Q8NI38 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra NFKBID Q8NI38 SAMD11 Homo sapiens Q96NU1
Validated Y2H
32296183
Intra NFKBID Q8NI38 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra NFKBID Q8NI38 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 SNAPC3 Homo sapiens Q92966
Y2H Array
32296183
Intra NFKBID Q8NI38 SNAPC3 Homo sapiens Q92966
Validated Y2H
32296183
Intra NFKBID Q8NI38 SNAPC3 Homo sapiens Q92966
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 DTX3 Homo sapiens Q8N9I9
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 DTX3 Homo sapiens Q8N9I9
Y2H Array
32296183
Intra NFKBID Q8NI38 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra NFKBID Q8NI38 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 MRPL53 Homo sapiens Q96EL3
Validated Y2H
32296183
Intra NFKBID Q8NI38 SMG9 Homo sapiens Q9H0W8
Validated Y2H
32296183
Intra NFKBID Q8NI38 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra NFKBID Q8NI38 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 KRT76 Homo sapiens Q01546
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 KRT76 Homo sapiens Q01546
Y2H Array
32296183
Intra NFKBID Q8NI38 ARHGEF2 Homo sapiens Q92974
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 ARHGEF2 Homo sapiens Q92974
Validated Y2H
32296183
Intra NFKBID Q8NI38 ARHGEF2 Homo sapiens Q92974
Y2H Array
32296183
Intra NFKBID Q8NI38 PRMT7 Homo sapiens Q9NVM4
Validated Y2H
32296183
Intra NFKBID Q8NI38 SMAD4 Homo sapiens Q13485
Y2H Array
32296183
Intra NFKBID Q8NI38 SMAD4 Homo sapiens Q13485
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 VIM Homo sapiens P08670
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 VIM Homo sapiens P08670
Y2H Array
32296183
Intra NFKBID Q8NI38 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra NFKBID Q8NI38 GADD45GIP1 Homo sapiens Q8TAE8
Validated Y2H
32296183
Intra NFKBID Q8NI38 TSSK3 Homo sapiens Q96PN8
Validated Y2H
32296183
Intra NFKBID Q8NI38 HOXD3 Homo sapiens P31249
Y2H Array
32296183
Intra NFKBID Q8NI38 HOXD3 Homo sapiens P31249
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 UTP23 Homo sapiens Q9BRU9
Validated Y2H
32296183
Intra NFKBID Q8NI38 RBM4B Homo sapiens Q9BQ04
Validated Y2H
32296183
Intra NFKBID Q8NI38 RBM41 Homo sapiens Q96IZ5
Validated Y2H
32296183
Intra NFKBID Q8NI38 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra NFKBID Q8NI38 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra NFKBID Q8NI38 TCF19 Homo sapiens Q9Y242
Validated Y2H
32296183
Intra NFKBID Q8NI38 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra NFKBID Q8NI38 GFAP Homo sapiens P14136
Y2H Array
32296183
Intra NFKBID Q8NI38 GFAP Homo sapiens P14136
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 BEX2 Homo sapiens Q9BXY8
Validated Y2H
32296183
Intra NFKBID Q8NI38 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra NFKBID Q8NI38 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra NFKBID Q8NI38 PAX6 Homo sapiens P26367
Y2H Array
32296183
Intra NFKBID Q8NI38 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
Intra NFKBID Q8NI38 TEKT4 Homo sapiens Q8WW24
Validated Y2H
32296183
Intra NFKBID Q8NI38 IHO1 Homo sapiens Q8IYA8
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 IHO1 Homo sapiens Q8IYA8
Y2H Array
32296183
Intra NFKBID Q8NI38 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Intra NFKBID Q8NI38 DDX25 Homo sapiens Q9UHL0
Validated Y2H
32296183
Intra NFKBID Q8NI38 C1orf94 Homo sapiens Q6P1W5
Y2H Prey Pooling
25416956
Intra NFKBID Q8NI38 C1orf94 Homo sapiens Q6P1W5
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 C1orf94 Homo sapiens Q6P1W5
Y2H Array
32296183
Intra NFKBID Q8NI38 C1orf94 Homo sapiens Q6P1W5
Validated Y2H
25416956
Intra NFKBID Q8NI38 GIGYF1 Homo sapiens O75420
Y2H Prey Pooling
32296183
Intra NFKBID Q8NI38 GIGYF1 Homo sapiens O75420
Y2H Array
32296183
Intra NFKBID Q8NI38 RBM14 Homo sapiens Q96PK6
Validated Y2H
32296183
Intra NFKBID Q8NI38 DMRT3 Homo sapiens Q9NQL9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09262 NFKBID Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NFKBID VGNC VGNC:53742
Felis catus NFKBID VGNC VGNC:63790
Macaca mulatta NFKBID VGNC VGNC:75179
Bos taurus NFKBID VGNC VGNC:32047
Mus musculus NFKBID MGD MGI:3041243
Rattus norvegicus NFKBID RGD RGD:1308055