2. Anti-infection
  3. Bacterial
  4. HAP-1

HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a proapoptotic peptide DP2.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HAP-1 Chemical Structure

HAP-1 Chemical Structure

CAS No. : 329004-38-8

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Based on 1 publication(s) in Google Scholar

HAP-1 Related Antibodies

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Description

HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a proapoptotic peptide DP2[1].

Molecular Weight

1335.47

Formula

C60H90N18O17
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ser-Phe-His-Gln-Phe-Ala-Arg-Ala-Thr-Leu-Ala-Ser
Sequence Shortening

SFHQFARATLAS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (74.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7488 mL 3.7440 mL 7.4880 mL
5 mM 0.1498 mL 0.7488 mL 1.4976 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7488 mL 3.7440 mL 7.4880 mL 18.7200 mL
5 mM 0.1498 mL 0.7488 mL 1.4976 mL 3.7440 mL
10 mM 0.0749 mL 0.3744 mL 0.7488 mL 1.8720 mL
15 mM 0.0499 mL 0.2496 mL 0.4992 mL 1.2480 mL
20 mM 0.0374 mL 0.1872 mL 0.3744 mL 0.9360 mL
25 mM 0.0300 mL 0.1498 mL 0.2995 mL 0.7488 mL
30 mM 0.0250 mL 0.1248 mL 0.2496 mL 0.6240 mL
40 mM 0.0187 mL 0.0936 mL 0.1872 mL 0.4680 mL
50 mM 0.0150 mL 0.0749 mL 0.1498 mL 0.3744 mL
60 mM 0.0125 mL 0.0624 mL 0.1248 mL 0.3120 mL
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HAP-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HAP-1329004-38-8HAP1HAP 1BacterialInhibitorinhibitorinhibit

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