Moslosooflavone

Name: Moslosooflavone
Brand: MedChemExpress
SKU: HY-N2035
Rating: 4.5 (1 reviews)

Cat. No.: HY-N2035 Purity: 99.71%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities.

For research use only. We do not sell to patients.

Moslosooflavone Chemical Structure

CAS No. : 3570-62-5

Size	Price	Stock	Quantity
5 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Moslosooflavone:

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
DLD-1	IC₅₀	> 20 μM Compound: 6a	Antiproliferative activity against human DLD1 cells after 48 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HepG2	IC₅₀	2.72 μM Compound: 6a	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HT-22	EC₅₀	> 100 μM Compound: 14	Neuroprotective activity against glutamate-induced cell death in mouse HT-22 cells assessed as increase in cell viability after 24 hrs by EZ-Cytox assay Neuroprotective activity against glutamate-induced cell death in mouse HT-22 cells assessed as increase in cell viability after 24 hrs by EZ-Cytox assay	[PMID: 32991171]
HT-29	IC₅₀	> 20 μM Compound: 6a	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
SW480	IC₅₀	> 20 μM Compound: 6a	Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay	10.1039/C5MD00163C

In Vitro

Moslosooflavone can significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

298.29

Formula

C₁₇H₁₄O₅

CAS No.

3570-62-5

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(OC)=CC(O)=C13

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (33.52 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3524 mL	16.7622 mL	33.5244 mL
5 mM	0.6705 mL	3.3524 mL	6.7049 mL
10 mM	0.3352 mL	1.6762 mL	3.3524 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.71%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (250 KB) RP-HPLC (164 KB)

Handling Instructions (2659 KB)

References

[1]. Lin-lin Jing, et al. Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata. Zhong Yao Cai. 2015 Jan;38(1):89-92. [Content Brief]

[2]. Jing LL, et al. Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata. Zhong Yao Cai. 2015 Jan;38(1):89-92.

[3]. Chao WW, et al.Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition.J Agric Food Chem. 2010 Feb 24;58(4):2505-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3524 mL	16.7622 mL	33.5244 mL	83.8111 mL
	5 mM	0.6705 mL	3.3524 mL	6.7049 mL	16.7622 mL
	10 mM	0.3352 mL	1.6762 mL	3.3524 mL	8.3811 mL
	15 mM	0.2235 mL	1.1175 mL	2.2350 mL	5.5874 mL
	20 mM	0.1676 mL	0.8381 mL	1.6762 mL	4.1906 mL
	25 mM	0.1341 mL	0.6705 mL	1.3410 mL	3.3524 mL
	30 mM	0.1117 mL	0.5587 mL	1.1175 mL	2.7937 mL