2. Metabolic Enzyme/Protease
  3. Lipase
  4. PF-07853578

PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma.

For research use only. We do not sell to patients.

PF-07853578 Chemical Structure

PF-07853578 Chemical Structure

CAS No. : 3036158-98-9

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PF-07853578 Related Antibodies

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Description

PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma[1].

Molecular Weight

408.85

Formula

C16H19ClF2N2O4S
CAS No.
SMILES

O=S1(N(CC[C@H]1C)[C@H]2CN(CC(F)(C2)F)C(OC3=CC=C(C=C3)Cl)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-07853578 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PF-078535783036158-98-9PF07853578PF 07853578LipasePatatin-like phospholipase domain-containing protein 3PNPLA3fatty liverNALFDInhibitorinhibitorinhibit

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PF-07853578
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HY-163959
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