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Isoforms Recommended:	Aromatase/CYP19A1

Results for "

Aromatase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (2) Antibiotic (1) Apoptosis (4) Aryl Hydrocarbon Receptor (3) Autophagy (3) Bacterial (2) Cytochrome P450 (56) Drug Metabolite (3) Endogenous Metabolite (1) Estrogen Receptor/ERR (8) Fluorescent Dye (1) Fungal (4) Isotope-Labeled Compounds (7) Monoamine Oxidase (3) NO Synthase (1) Parasite (3) Phosphodiesterase (PDE) (2) PPAR (2) Progesterone Receptor (3) Prostaglandin Receptor (2) PROTACs (1)
By Research Areas:	Cancer (45) Cardiovascular Disease (4) Endocrinology (25) Infection (5) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (3)

By Targets:

Androgen Receptor (2)

Antibiotic (1)

Apoptosis (4)

Aryl Hydrocarbon Receptor (3)

Autophagy (3)

Bacterial (2)

Cytochrome P450 (56)

Drug Metabolite (3)

Endogenous Metabolite (1)

Estrogen Receptor/ERR (8)

Fluorescent Dye (1)

Fungal (4)

Isotope-Labeled Compounds (7)

Monoamine Oxidase (3)

NO Synthase (1)

Parasite (3)

Phosphodiesterase (PDE) (2)

PPAR (2)

Progesterone Receptor (3)

Prostaglandin Receptor (2)

PROTACs (1)

By Research Areas:

Cancer (45)

Cardiovascular Disease (4)

Endocrinology (25)

Infection (5)

Inflammation/Immunology (5)

Metabolic Disease (3)

Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148430

Aromatase-IN-2	Cytochrome P450	Cancer
Aromatase-IN-2 is a potent *aromatase* inhibitor with an IC₅₀ value of 1.5 µM .

HY-150775

*Nonsteroidal aromatase* inhibitor 1**	Cytochrome P450	Cancer
Nonsteroidal aromatase inhibitor 1 (Compound 13h) is a nonsteroidal *aromatase* (CYP19A1) inhibitor (IC₅₀=0.09 nM). Nonsteroidal aromatase inhibitor 1 has potential for breast cancer research . Nonsteroidal aromatase inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-13632

Exemestane 4 Publications Verification FCE 24304; EXE	Cytochrome P450	Endocrinology Cancer
Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-162105

Aromatase-IN-3	Cytochrome P450	Endocrinology Cancer
Aromatase-IN-3 (compound 7d) is an *aromatase* inhibitor with an IC₅₀ of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research .

HY-144824

*Monoamine oxidase/Aromatase-IN-1*	Cytochrome P450 Monoamine Oxidase	Neurological Disease Cancer
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a highly potent monoamine oxidase (MAO) and *aromatase* dual inhibitor with IC₅₀s of 39 nM and 31 nM for MAO-B and aromatase, respectively. Monoamine oxidase/Aromatase-IN-1 can be used for researching neurological disorder and breast cancer .

HY-N9551

Eriodictyol chalcone	Cytochrome P450	Metabolic Disease
Eriodictyol chalcone possesses both anti-aromatase and an anti-17β-HSD activity .

HY-W739700

(R)-(+)-Aminoglutethimide L-Tartrate d-Aminoglutethimide L-Tartrate	Cytochrome P450	Inflammation/Immunology
(R)-(+)-Aminoglutethimide (L-Tartrate) is an inhibitor of *aromatase. (R)-(+)-Aminoglutethimide inhibits androstenedione with a K_i* value of 0.3 μM .

HY-137931

Testololactone	Others	Cancer
Testololactone is an *aromatase* inhibitor. Testololactone can be used for research of breast carcinoma .

HY-19599A

(Rac)-Vorozole (Rac)-R83842	Others	Others
(Rac)-Vorozole ((Rac)-R83842) is a racemate of Vorozole. Vorozole (HY-19599) is a potent and selective, orally active non-steroidal aromatase inhibitor .

HY-159741

Minamestane FCE 24928	Others	Cancer
Minamestane (FCE 24928) is a selective and competitive *aromatase* inhibitor with an IC₅₀ value of 45.7 nM. Minamestane is promising for research of postmenopausal breast cancer .

HY-118407

LY56110	Cytochrome P450 Monoamine Oxidase	Neurological Disease
LY56110 is an orally active *aromatase* inhibitor. LY56110 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC₅₀ of 2.5 and 11 μΜ, respectively. LY56110 can be used for neurological disorder study .

HY-105184

YM511	Cytochrome P450	Endocrinology
YM511 is a highly specific non-steroidal *aromatase* inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones .

HY-13632S5

Exemestane-13C,d2 FCE 24304-¹³C,d₂; EXE-¹³C,d₂	Cytochrome P450 Isotope-Labeled Compounds	Endocrinology Cancer
Exemestane- ¹³C,d₂ is ¹³C and deuterated labeled Exemestane (HY-13632). Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-P2906

Cytochrome P450 reductase	Cytochrome P450	Others
Cytochrome P450 reductase is a NADPH-cytochrome reductase. Cytochrome P450 reductase has a role in promoting aromatase conformation optimal for substrate binding .

HY-14248

Letrozole Maximum Cited Publications 16 Publications Verification CGS 20267	Cytochrome P450 Autophagy	Cancer
Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of *aromatase, with an IC₅₀* of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer .

HY-14248R

Letrozole (Standard)	Cytochrome P450 Autophagy	Cancer
Letrozole (Standard) is the analytical standard of Letrozole. This product is intended for research and analytical applications. Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer .

HY-113986

Dexfadrostat (R)-Fadrozole; (R)-CGS 16949A free base; FAD286	Others	Cardiovascular Disease
Dexfadrostat ((R)-Fadrozole) is a potent nonsteroidal inhibitor . Dexfadrostat also inhibits human placental aromatase (pIC₅₀ = 6.17) and aldosterone biosynthesis. Dexfadrostat reverses cardiac fibrosis in spontaneously hypertensive heart failure rats. .

HY-W087008

7-Hydroxyflavanone	Cytochrome P450	Endocrinology Cancer
7-Hydroxyflavanone is a potent inhibitor of *aromatase* (CYP19) activity with the IC₅₀ of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula

HY-113986B

(S)-Dexfadrostat (S)-Fadrozole; (S)-CGS 16949A free base; (S)-FAD286	Others	Inflammation/Immunology Endocrinology Cancer
(S)-Dexfadrostat ((S)-Fadrozole) is an aromatase inhibitor with an IC₅₀ of 4.6 nM in human placental microsomes in vitro. (S)-Dexfadrostat can be used in the study of estrogen-dependent breast cancer, gynecomastia, and systemic lupus erythematosus .

HY-13558

Atamestane SH 489	Estrogen Receptor/ERR	Endocrinology
Atamestane (SH 489) is a specific aromatase inhibitor, which selectively blocks the estrogen biosynthesis resulting from the aromatization of androstenedione and testosterone. Atamestane is a competitive and irreversible inhibitor of estrogen biosynthesis. Atamestane can be used for the research of benign prostatic hyperplasia (BPH) .

HY-152250

Antibacterial agent 132	Cytochrome P450 Bacterial	Infection
Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC₉₀ values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC₅₀ of 0.047μM .

HY-136063

Mefentrifluconazole	Fungal Cytochrome P450	Infection
Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (K_d= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC₅₀=0.92 μM) .

HY-118178

LY43578	Cytochrome P450 Monoamine Oxidase	Cardiovascular Disease
LY43578 is an orally active *aromatase* inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC₅₀ of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study .

HY-155493

CYP19A1/CYP11B2-IN-1	Cytochrome P450	Cancer
CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective *aromatase* and aldosterone synthase dual inhibitor with IC₅₀s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer .

HY-N0292

Oleuropein 2 Publications Verification	Cytochrome P450 PPAR Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits *aromatase* .

HY-B0845

Prochloraz BTS 40542	Fungal Estrogen Receptor/ERR Androgen Receptor Aryl Hydrocarbon Receptor	Infection Endocrinology
Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an *aromatase* inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC₅₀ of 1 μM .

HY-14274

Anastrozole 4 Publications Verification ZD1033	Cytochrome P450	Cancer
Anastrozole is a potent, highly selective *aromatase* inhibitor, which inhibits human placental aromatase with an IC₅₀ of 15 nM.

HY-N0292R

Oleuropein (Standard)	Cytochrome P450 PPAR Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Oleuropein (Standard) is the analytical standard of Oleuropein. This product is intended for research and analytical applications. Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase .

HY-B0845R

Prochloraz (Standard)	Fungal Estrogen Receptor/ERR Androgen Receptor Aryl Hydrocarbon Receptor	Infection Endocrinology
Prochloraz (Standard) is the analytical standard of Prochloraz. This product is intended for research and analytical applications. Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC₅₀ of 1 μM .

HY-14274R

Anastrozole (Standard) ZD1033 (Standard)	Cytochrome P450	Cancer
Anastrozole (Standard) is the analytical standard of Anastrozole. This product is intended for research and analytical applications. Anastrozole is a potent, highly selective *aromatase* inhibitor, which inhibits human placental aromatase with an IC₅₀ of 15 nM.

HY-14274S

Anastrozole-d12 ZD1033-d₁₂	Isotope-Labeled Compounds Cytochrome P450	Cancer
Anastrozole-d₁₂ is the deuterium labeled Anastrozole. Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM[1][2].

HY-U00176

Org30958	Cytochrome P450	Metabolic Disease
Org30958 is a potent *aromatase* inhibitor in vivo.

HY-B0237

Aminoglutethimide DL-Aminoglutethimide	Cytochrome P450	Endocrinology
Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM.

HY-N5012

Eurycomanone Pasakbumin A	Phosphodiesterase (PDE)	Endocrinology
Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

HY-14247

Fadrozole hydrochloride 2 Publications Verification CGS 16949A; (Rac)-FAD286 hydrochloride	Cytochrome P450	Endocrinology Cancer
Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of *aromatase* with an IC₅₀ of 6.4 nM.

HY-13632S

Exemestane-d2 FCE 24304-d₂; EXE-d₂	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-13632S2

Exemestane-d3 FCE 24304-d₃; EXE-d₃	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane-d₃ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-14247A

Fadrozole 2 Publications Verification CGS 16949A free base; (Rac)-FAD286	Cytochrome P450	Cancer
Fadrozole (CGS 16949A free base) is a potent, selective and nonsteroidal inhibitor of *aromatase* with an IC₅₀ of 6.4 nM.

HY-N7128

Flavanone	Cytochrome P450	Cancer
Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) .

HY-13632S1

Exemestane-13C3	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane- ¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-13632R

Exemestane (Standard) 4 Publications Verification FCE 24304(Standard); EXE (Standard)	Cytochrome P450	Endocrinology Cancer
Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-W392925

(R)-(+)-Aminoglutethimide d-Aminoglutethimide	Cytochrome P450	Cancer
(R)-(+)-Aminoglutethimide is a potent and orally active *aromatase* inhibitor. (R)-(+)-Aminoglutethimide has the potential for the research of breast cancer .

HY-135023

5-trans-PGE2 5-trans Prostaglandin E2	Cytochrome P450 Prostaglandin Receptor	Cancer
5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer .

HY-146688

SYN20028567	Cytochrome P450	Cancer
SYN20028567 is an aromatase (CYP19) inhibitor with an IC₅₀ of 9.4 nM. SYN20028567 can be used for breast cancer research .

HY-105375

FR 901537	Cytochrome P450	Cancer
FR 901537 is a potent and competitive *aromatase* inhibitor. FR 901537, a novel naphthol derivative, has the potential for breast cancer research .

HY-163884

BDE33872639	Cytochrome P450	Cancer
BDE33872639 shows stable binding interactions with the aromatase enzyme and identifies as a non-blocker, demonstrating a reduced risk of adversecardiac effects in virtual screening .

HY-N5012R

Eurycomanone (Standard)	Phosphodiesterase (PDE)	Endocrinology
Eurycomanone (Standard) is the analytical standard of Eurycomanone. This product is intended for research and analytical applications. Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

HY-105163

Finrozole MPV-2213ad	Cytochrome P450	Endocrinology
Finrozole (MPV-2213ad) is a nonsteroidal, orally active and competitive *aromatase* enzyme inhibitor. Finrozole can be used for urinary symptoms research .

HY-167737

(-)-Vorozole	Others	Cancer
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potent and selective properties. (-)-Vorozole demonstrates antitumor activity in in vivo experiments. (-)-Vorozole is utilized in the study of breast cancer.

HY-N8405

Isolimonexic acid	Cytochrome P450	Cancer
Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and *anti-aromatase* (IC₅₀=25.60 μM) properties .

Cat. No.	Product Name	Type

HY-116862

Dibenzylfluorescein

DBF

Fluorescent Dyes/Probes

Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its K_m value of 0.87-1.9 µM (Ex=485nm，Em=535nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .

Cat. No.	Product Name	Type

HY-W699238

S-(-)-Aminoglutethimide D-tartrate

Cell Assay Reagents

S-(-)-Aminoglutethimide D-tartrate is an aromatase inhibitor with activity that blocks adrenal steroidogenesis. S-(-)-Aminoglutethimide D-tartrate can be used to inhibit steroid-related diseases. S-(-)-Aminoglutethimide D-tartrate is often used clinically to control certain types of cancer. S-(-)-Aminoglutethimide D-tartrate effectively reduces testosterone and estrogen levels through an enzyme inhibition mechanism.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-14248

Letrozole Maximum Cited Publications 16 Publications Verification CGS 20267	Alkaloids Classification of Application Fields Other Alkaloids Source classification Plants Compositae Disease Research Fields Tephrosia purpurea (L.) Pers. Cancer	Cytochrome P450 Autophagy
Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of *aromatase, with an IC₅₀* of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer .

HY-N0292

Oleuropein 2 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Anti-aging Source classification Plants Burseraceae Iridoids Canarium album (Lour.) Rauesch. Terpenoids Phenols Polyphenols Inflammation/Immunology Disease Research Fields Cancer	Cytochrome P450 PPAR Apoptosis
Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits *aromatase* .

HY-N5012

Eurycomanone Pasakbumin A	Structural Classification other families Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Endocrinology	Phosphodiesterase (PDE)
Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

HY-N7128

Flavanone	Structural Classification Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Sophora flavescens Aiton Plants Disease Research Fields Cancer	Cytochrome P450
Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) .

HY-N9551

Eriodictyol chalcone	Structural Classification Chalcones Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Plants Umbelliferae Disease Research Fields	Cytochrome P450
Eriodictyol chalcone possesses both anti-aromatase and an anti-17β-HSD activity .

HY-14248R

Letrozole (Standard)	Alkaloids Other Alkaloids Source classification Plants Compositae Tephrosia purpurea (L.) Pers.	Cytochrome P450 Autophagy
Letrozole (Standard) is the analytical standard of Letrozole. This product is intended for research and analytical applications. Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer .

HY-W087008

7-Hydroxyflavanone	Dalbergia cochinchinensis Monophenols Source classification Papilionaceae Phenols Plants Disease Research Fields Endocrinology Cancer	Cytochrome P450
7-Hydroxyflavanone is a potent inhibitor of *aromatase* (CYP19) activity with the IC₅₀ of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula

HY-N0292R

Oleuropein (Standard)	Structural Classification Iridoids Canarium album (Lour.) Rauesch. Terpenoids Source classification Phenols Polyphenols Plants Burseraceae	Cytochrome P450 PPAR Apoptosis
Oleuropein (Standard) is the analytical standard of Oleuropein. This product is intended for research and analytical applications. Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity . Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase .

HY-105375

FR 901537	Structural Classification Monophenols Microorganisms Source classification Phenols	Cytochrome P450
FR 901537 is a potent and competitive *aromatase* inhibitor. FR 901537, a novel naphthol derivative, has the potential for breast cancer research .

HY-N5012R

Eurycomanone (Standard)	Structural Classification other families Terpenoids Source classification Diterpenoids Plants	Phosphodiesterase (PDE)
Eurycomanone (Standard) is the analytical standard of Eurycomanone. This product is intended for research and analytical applications. Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

HY-N8405

Isolimonexic acid	Structural Classification Natural Products Classification of Application Fields Citrus limon (L.) Burm. F. Source classification Rutaceae Plants Disease Research Fields Cancer	Cytochrome P450
Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and *anti-aromatase* (IC₅₀=25.60 μM) properties .

HY-N7128R

Flavanone (Standard)	Structural Classification Flavonoids Leguminosae Flavonones Source classification Sophora flavescens Aiton Plants	Cytochrome P450
Flavanone (Standard) is the analytical standard of Flavanone. This product is intended for research and analytical applications. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) .

HY-N3246

Morachalcone A	Structural Classification Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	NO Synthase
Morachalcone A is a naturally-occurring aromatase inhibitor (IC₅₀=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production .

HY-113062

20α-Dihydroprogesterone 20-OH-P	Structural Classification Animals Source classification Steroids	Endogenous Metabolite Cytochrome P450
20α-Dihydroprogesterone is the metabolite of Progesterone (HY-N0437). 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits *aromatase* in cell MCF-7aro with IC₅₀ about 5 μM .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N1993

5-Methyl-7-methoxyisoflavone 1 Publications Verification	Structural Classification Flavonoids other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields Isoflavones	Cytochrome P450
5-Methyl-7-methoxyisoflavone is an orally active anti-oxidant with remyelinating activity. 5-Methyl-7-methoxyisoflavone inhibits the enzyme *aromatase, interfering with the normal metabolic pathways of testosterone. 5-Methyl-7-methoxyisoflavone is a non-steroidal anabolic isoflavone, used as a anabolic agent*. 5-Methyl-7-methoxyisoflavone shows better potency increasing muscle mass and endurance than Ipriflavone (HY-N0094). 5-Methyl-7-methoxyisoflavone can be used for fat loss besides the maintenance of low cholesterol level and strengthen bones .

Cat. No.	Product Name	Chemical Structure

HY-14248S

Letrozole-d4
Letrozole-d₄ (CGS 20267-d4) is the deuterium labeled Letrozole. Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer[1][2][3].

HY-13632S5

Exemestane-13C,d2
Exemestane- ¹³C,d₂ is ¹³C and deuterated labeled Exemestane (HY-13632). Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-14274S

Anastrozole-d12
Anastrozole-d₁₂ is the deuterium labeled Anastrozole. Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM[1][2].

HY-13632S

Exemestane-d2
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-13632S2

Exemestane-d3
Exemestane-d₃ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-13632S1

Exemestane-13C3
Exemestane- ¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-18719ES

Endoxifen-d5
Endoxifen-d₅ is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study[1][2].

HY-B0084S4

Dienogest-13C,15N,d4

Dienogest-13C,15N,d4 (STS 557-13C,15N,d4) is the ¹³C, ¹⁵N and deuterium labeled isotope of Dienogest (HY-B0084). Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE₂ synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia .

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HY-P80547

	Aromatase Antibody CYP19A1; ARO1; CYAR; CYP19; Cytochrome P450 19A1; Aromatase; CYPXIX; Cytochrome P-450AROM; Estrogen synthase	WB, IP	Human, Mouse, Rat
	Aromatase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 58 kDa, targeting to Aromatase. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

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