7-Hydroxyflavanone

Cat. No.: HY-W087008 Purity: 99.59%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

7-Hydroxyflavanone is a potent inhibitor of aromatase (CYP19) activity with the IC₅₀ of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula

For research use only. We do not sell to patients.

7-Hydroxyflavanone Chemical Structure

CAS No. : 6515-36-2

Size	Stock	Quantity
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms

CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Aromatase

Molecular Weight

240.25

Formula

C₁₅H₁₂O₃

CAS No.

6515-36-2

Appearance

Solid

Color

White to off-white

SMILES

O=C1CC(C2=CC=CC=C2)OC3=C1C=CC(O)=C3

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (520.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1623 mL	20.8117 mL	41.6233 mL
5 mM	0.8325 mL	4.1623 mL	8.3247 mL
10 mM	0.4162 mL	2.0812 mL	4.1623 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.59%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (248 KB) HNMR (236 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Sanderson JT, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9. [Content Brief]

[2]. J Thomas Sanderson, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.1623 mL	20.8117 mL	41.6233 mL	104.0583 mL
	5 mM	0.8325 mL	4.1623 mL	8.3247 mL	20.8117 mL
	10 mM	0.4162 mL	2.0812 mL	4.1623 mL	10.4058 mL
	15 mM	0.2775 mL	1.3874 mL	2.7749 mL	6.9372 mL
	20 mM	0.2081 mL	1.0406 mL	2.0812 mL	5.2029 mL
	25 mM	0.1665 mL	0.8325 mL	1.6649 mL	4.1623 mL
	30 mM	0.1387 mL	0.6937 mL	1.3874 mL	3.4686 mL
	40 mM	0.1041 mL	0.5203 mL	1.0406 mL	2.6015 mL
	50 mM	0.0832 mL	0.4162 mL	0.8325 mL	2.0812 mL
	60 mM	0.0694 mL	0.3469 mL	0.6937 mL	1.7343 mL
	80 mM	0.0520 mL	0.2601 mL	0.5203 mL	1.3007 mL
	100 mM	0.0416 mL	0.2081 mL	0.4162 mL	1.0406 mL