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Glucan

" in MedChemExpress (MCE) Product Catalog:

55

Inhibitors & Agonists

1

Fluorescent Dye

12

Biochemical Assay Reagents

1

Peptides

15

Natural
Products

11

Recombinant Proteins

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W145521

    β Glucan

    Biochemical Assay Reagents IKK NO Synthase Bacterial Infection Inflammation/Immunology Cancer
    β-1,3-GlucanGlucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors .
    β-1,3-Glucan
  • HY-134816

    Toll-like Receptor (TLR) Metabolic Disease Inflammation/Immunology Cancer
    D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism) .
    D-Glucan
  • HY-159114

    Biochemical Assay Reagents Inflammation/Immunology
    Whole Glucan Particles is a Dectin-1a agonist. Whole Glucan Particles activates the innate immune system to improve the function of macrophages, monocytes and other immune cells .
    Whole Glucan Particles
  • HY-134655

    Fungal Infection Inflammation/Immunology
    D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity .
    D75-4590
  • HY-139413

    Toll-like Receptor (TLR) Cancer
    β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .
    β-D-Glucan
  • HY-147295

    BTH 1677; Imprime PGG

    Toll-like Receptor (TLR) Inflammation/Immunology Cancer
    Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .
    Odetiglucan
  • HY-149330

    Bacterial Infection
    HA5 inhibits Streptococcus mutans biofilm with an IC50 value of 6.42 μM, without affecting its growth. HA5 also inhibits Streptococcus mutans glucan production and eDNA levels .
    HA5
  • HY-B2193A

    1,4-alpha-D-Glucan-Glucanohydrolase, ptyalin

    Biochemical Assay Reagents Others
    α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase, ptyalin) is a biological material or organic compound that can be used in life science research .
    α-Amylase, Human Saliva
  • HY-B2193B

    Amylase, a-Amylase, 1,4-a-D-Glucan Glucanohydrolase, glycogenase

    Biochemical Assay Reagents Others
    α-Amylase, Human Pancreas (Amylase, a-Amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase) is a biological material or organic compound that can be used in life science research .
    α-Amylase, Human Pancreas
  • HY-B2193C

    1,4-alpha-D-Glucan-Glucanohydrolase, amy2, PPA, PA

    Amylases Others
    α-Amylase, Porcine Pancreatic (1,4-alpha-D-Glucan-glucanohydrolase, amy2, PPA, PA) is a biological material or organic compound that can be used in life science research .
    α-Amylase, Porcine Pancreatic
  • HY-N8537

    Fungal Infection
    Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .
    Enfumafungin
  • HY-158082C

    Tetramethyl rhodamine isothiocyanate Glucan, MW 70000

    Fluorescent Dye Others
    TRITC-dextran, MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye, with the molecular weight of 70 kD. TRITC-dextran, MW 70000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 70000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 70000
  • HY-158082E

    Tetramethyl rhodamine isothiocyanate Glucan, MW 500000

    Fluorescent Dye Others
    TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 500000
  • HY-158082D

    Tetramethyl rhodamine isothiocyanate Glucan, MW 150000

    Fluorescent Dye Others
    TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 150000
  • HY-158082H

    Tetramethyl rhodamine isothiocyanate Glucan, MW 2000000

    Fluorescent Dye Others
    TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 2000000
  • HY-158082
    TRITC-dextran, MW 4000
    1 Publications Verification

    Tetramethyl rhodamine isothiocyanate Glucan, MW 4000

    Fluorescent Dye Others
    TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 4000
  • HY-158082A

    Tetramethyl rhodamine isothiocyanate Glucan, MW 20000

    Fluorescent Dye Others
    TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 20000
  • HY-158082B

    Tetramethyl rhodamine isothiocyanate Glucan, MW 40000

    Fluorescent Dye Others
    TRITC-dextran, MW 40000 (Tetramethyl rhodamine isothiocyanate glucan, MW 40000) is a fluorescent dye, with the molecular weight of 40 kD. TRITC-dextran MW 40000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 40000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 40000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
    TRITC-dextran, MW 40000
  • HY-145348

    Fungal Infection
    MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.
    MK-5204
  • HY-119109
    Laminaran
    1 Publications Verification

    Endogenous Metabolite Cancer
    Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
    Laminaran
  • HY-107126B

    MK 3118 phosphate; SCY-078 phosphate

    Fungal Infection
    Ibrexafungerp phosphate is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp phosphate can be used for research of Candida and Aspergillus infections .
    Ibrexafungerp phosphate
  • HY-107126

    MK 3118; SCY-078

    Fungal Infection
    Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .
    Ibrexafungerp
  • HY-107126A

    MK 3118 citrate; SCY-078 citrate

    Fungal Infection
    Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .
    Ibrexafungerp citrate
  • HY-N14471

    Fungal Infection
    Fusacandin A inhibits (1,3)-β-glucan synthetase and has antifungal properties .
    Fusacandin A
  • HY-N14472

    Fungal Infection
    Fusacandin B inhibits (1,3)-β-glucan synthetase and has antifungal properties .
    Fusacandin B
  • HY-16321
    Micafungin sodium
    Maximum Cited Publications
    16 Publications Verification

    FK 463 sodium

    Fungal Antibiotic Infection Cancer
    Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
    Micafungin sodium
  • HY-N13873

    Fungal Infection
    Saricandin has weak antifungal activity. Saricandin inhibits glucan synthase with an ID50 of 242.0 μg/mL .
    Saricandin
  • HY-P3004

    Lyticase

    Endogenous Metabolite Others
    Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .
    Endo-1,3-β-glucanase
  • HY-164071

    Biochemical Assay Reagents Others
    Carboxymethyl Dextran (CM-Dextran) is a dextran with carboxymethyl substituted hydroxyl groups. It has good hydrophilicity and ionic properties and can be used as a biomaterial or organic compound for life science related research .
    Carboxymethyl Dextran (CM-Dextran)
  • HY-W050145

    1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose

    Endogenous Metabolite Metabolic Disease
    Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
    Levoglucosan
  • HY-17579

    FK463

    Fungal Antibiotic Infection Cancer
    Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.
    Micafungin
  • HY-E70013

    endo-1,3:1,4-β-D-Glucanase

    Endogenous Metabolite Metabolic Disease
    Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .
    Lichenase, Microorganism
  • HY-17006A

    MK-0991; L-743872

    Antibiotic Fungal Bacterial Infection Cancer
    Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
    Caspofungin
  • HY-17006
    Caspofungin diacetate
    5+ Cited Publications

    MK-0991 diacetate; L-743872 diacetate

    Fungal Antibiotic Bacterial Infection Cancer
    Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
    Caspofungin diacetate
  • HY-16321R

    Fungal Antibiotic Infection Cancer
    Micafungin (sodium) (Standard) is the analytical standard of Micafungin (sodium). This product is intended for research and analytical applications. Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
    Micafungin (sodium) (Standard)
  • HY-W050145S

    1,6-Anhydro-β-D-glucopyranose-d7; 1,6-Anhydro-β-D-glucose-d7

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[1][2].
    Levoglucosan-d7
  • HY-W050145R

    Endogenous Metabolite Metabolic Disease
    Levoglucosan (Standard) is the analytical standard of Levoglucosan. This product is intended for research and analytical applications. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
    Levoglucosan (Standard)
  • HY-W050145S2

    1,6-Anhydro-β-D-glucopyranose-13C6; 1,6-Anhydro-β-D-glucose-13C6

    Endogenous Metabolite Metabolic Disease
    Levoglucosan- 13C6 is the 13C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].
    Levoglucosan-13C6
  • HY-165126

    SPG

    Bacterial Parasite Infection Cancer
    Schizophyllan (SPG), a member of the β-glucan family, is an exopolysaccharide with antineoplastic, antibacterial activities and antiparasitic properties. Schizophyllan can be used for petroleum recovery, a thickener for cosmetic lotions, oxygen impermeable films for food preservation, and high-value pharmaceutical applications .
    Schizophyllan
  • HY-N8537R

    Fungal Infection
    Enfumafungin (Standard)
  • HY-17006R

    MK-0991 (diacetate) (Standard); L-743872 (diacetate) (Standard)

    Fungal Antibiotic Bacterial Infection Cancer
    Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
    Caspofungin (diacetate) (Standard)
  • HY-17006S

    MK-0991-d4 diacetate; L-743872-d4 diacetate

    Fungal Bacterial Antibiotic Infection
    Caspofungin-d4 (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].
    Caspofungin-d4 diacetate
  • HY-163462

    Fungal Infection
    Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants .
    Poacic acid
  • HY-N5160

    Antibiotic Fungal Infection
    Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .
    Arborcandin A
  • HY-N5165

    Antibiotic Fungal Infection
    Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC50 values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin F
  • HY-N5163

    Antibiotic Fungal Infection
    Arborcandin D is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC50 values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .
    Arborcandin D
  • HY-N5162

    Antibiotic Fungal Infection
    Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .
    Arborcandin C
  • HY-P2840

    Endogenous Metabolite Metabolic Disease
    Dextranase, Trichoderma reesei, glucan hydrolase, is often used in biochemical research. Dextranase can catalyze the hydrolysis of α-(1,6)-glucosidic bonds in dextran, and has a wide range of applications, such as food processing, sugar modification, agent preparation, and medicine for enhancing the activity of endocarditis antibiotics wait .
    Dextranase, Trichoderma reesei
  • HY-N5161

    Antibiotic Fungal Infection
    Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin B
  • HY-N5164

    Antibiotic Fungal Infection
    Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .
    Arborcandin E

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