Search Result

Isoforms Recommended:	MMP-1

Results for "

MMP-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MMP (84) Akt (1) Aminopeptidase (1) Androgen Receptor (1) Antibiotic (3) AP-1 (1) Apoptosis (6) Autophagy (2) Bacterial (6) CDK (1) Drug Metabolite (1) Endogenous Metabolite (6) Fluorescent Dye (3) Fungal (1) HIV Integrase (1) Isotope-Labeled Compounds (1) NF-κB (1) NO Synthase (2) p38 MAPK (1) PI3K (1) PKC (1) Reactive Oxygen Species (2) SARS-CoV (1) Small Interfering RNA (siRNA) (2) TGF-β Receptor (1) TNF Receptor (2)
By Research Areas:	Cancer (33) Cardiovascular Disease (5) Infection (6) Inflammation/Immunology (54) Metabolic Disease (1) Neurological Disease (3)
Oligonucleotides:	Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

MMP-1-IN-1	MMP	Cancer
MMP-1-IN-1 (Compound 6) is a highly potent *MMP-1* inhibitor with an IC₅₀ of 0.034 μM ^[1].

MMP13-IN-2	MMP	Inflammation/Immunology
MMP13-IN-2 is a potent, selective and orally active *MMP-13* inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC₅₀=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research ^[1].

BI-4394 MMP13-IN-3	MMP	Inflammation/Immunology
BI-4394 (MMP13-IN-3) is a potent, selective, and orally active *MMP-13* inhibitor (IC₅₀=1 nM ^[1]) for the potential treatment of osteoarthritis . BI-4394 is >1000 selective over other MMPs .

3,5,7-Trimethoxyflavone	Others	Inflammation/Immunology
3,5,7-Trimethoxyflavone, a flavonoid compound, can inhibit the TNF-α-induced high expression and secretion of MMP-1 by cells. 3,5,7-Trimethoxyflavone can be used to ameliorate skin damage ^[1].

MMP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 ^[1].Ex/Em = 340/440 nm

Isozedoarondiol	MMP	Others
Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes ^[1].

VPLSLYSG	MMP	Others
VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), *MMP-1* and *MMP-2. VPLSLYSG has potential applications in MMP* substrates ^[1] .

Exserohilone (-)-Exserohilone	Reactive Oxygen Species	Metabolic Disease
Exserohilone ((-)-Exserohilone) is a thiodiketopiperazine derivative that exhibits the inhibition of TNF-α-induced ROS generation and MMP-1 secretion. Exserohilone increases the procollagen type I α1 secretion in human dermal fibroblasts ^[1].

3,3′-Bisdemethylpinoresinol	MMP	Inflammation/Immunology
3,3′-Bisdemethylpinoresinol, lignin, is a nature product and has MMP-1 inhibitory activity in UVA-irradiated human dermal fibroblasts. 3,3′-Bisdemethylpinoresinol can be isolated from the seeds of Morinda citrifolia ^[1].

RS-104966	MMP	Others
RS-104966 is a potent **collagenase-1 (MMP-1)** inhibitor. RS-104966 induces a conformational change in the side chains of the S10 pocket of MMP-1 ^[1].

DL-Syringaresinol (±)-Syringaresinol	p38 MAPK AP-1 Bacterial	Infection
DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing *MAPK/AP-1* signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv ^[1] .

Ilomastat Maximum Cited Publications 40 Publications Verification GM6001; Galardin	MMP	Cancer
Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC₅₀s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a K_i of 0.4 nM for human skin fibroblast collagenase (MMP-1).

Triolein	MMP Endogenous Metabolite	Inflammation/Immunology
Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities ^[1] .

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	MMP	Others
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity ^[1] .

S-methyl-KE-298 M-2	MMP Drug Metabolite	Inflammation/Immunology
S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.

Triolein (Standard)	MMP Endogenous Metabolite	Inflammation/Immunology
Triolein (Standard) is the analytical standard of Triolein. This product is intended for research and analytical applications. Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities ^[1] .

Batimastat 5+ Cited Publications BB94	MMP	Cancer
Batimastat is a potent broad spectrum *MMP* inhibitor with IC₅₀ of 3, 4, 4, 6, and 20 nM for *MMP-1, MMP-2, MMP-9, MMP-7* and *MMP-3*, respectively.

Batimastat sodium salt BB-94 sodium salt	MMP	Cancer
Batimastat sodium salt is a potent broad spectrum *MMP* inhibitor with IC₅₀ of 3, 4, 4, 6, and 20 nM for *MMP-1, MMP-2, MMP-9, MMP-7* and *MMP-3*, respectively.

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 ^[1]. (Ex/Em=325 nm/400 nm)

CL-82198 hydrochloride	MMP	Others
CL-82198 hydrochloride is a selective inhibitor of *MMP-13. CL-82198 hydrochloride binds to the entire S1’ pocket of MMP-13, which is the basis of its selectivity against MMP-1, MMP*-9, and TACE ^[1].

MMP-7-IN-1	MMP	Cancer
MMP-7-IN-1 is a potent and selective inhibitor of *MMP-7* over MMP-1, -2, -3, -8, -9, -13 with an IC₅₀ value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis ^[1].

MMP-2 Inhibitor II	MMP	Cancer
MMP-2 Inhibitor II (compound 2) is a selective *MMP-2* inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively ^[1].

CGS 27023A	MMP	Inflammation/Immunology
CGS 27023A is a non-peptidic and orally active *MMP* inhibitor with the K_i values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A can be used for study of arthritis ^[1].

CP-471474	MMP	Inflammation/Immunology
CP-471474 is an orally active and pan *MMP* inhibitor, with IC₅₀ values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively ^[1] .

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) ^[1] .

DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH	Fluorescent Dye	Others
DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a K_m of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity ^[1].

Funalenone BMS-304245	Bacterial MMP HIV Integrase	Infection
Funalenone (BMS-304245) is a MraY + MurG inhibitor with an IC₅₀ of 25.5 μM in a MraY + MurG membrane plate assay. Funalenone inhibits Staphylococcus aureus (A15090) with an MIC of 64 μg/mL. Funalenone also inhibits *MMP-1* with an IC₅₀ of 170 μM ^[1] .

PG 116800 PG 530742; PGE 530742; PGE 7113313	MMP	Inflammation/Immunology
PG 116800 (PG 530742) is an orally avtive *MMP* inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research ^[1].

Cordycepin 5+ Cited Publications 3'-Deoxyadenosine	TNF Receptor MMP Bacterial Autophagy Antibiotic	Infection Inflammation/Immunology Cancer
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced *MMP-1* and *MMP-3* expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner ^[1]. Cordycepin kills *Mycobacterium tuberculosis* through hijacking the bacterial adenosine kinase .

Luteolin 7-O-glucuronide 2 Publications Verification Luteolin 7-glucuronide	MMP	Neurological Disease Inflammation/Immunology
Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases *(MMP)* activities, with IC₅₀s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively ^[1].

UK 356618 4 Publications Verification	MMP	Inflammation/Immunology Cancer
UK 356618 (Compound 4j) is a potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) with an IC₅₀ of 5.9 nM. UK 356618 is less potent against MMP-1, MMP-2, MMP-9, MMP-13 and MMP-14 compared with *MMP-3* ^[1].

XL-784 free base	MMP	Cardiovascular Disease
XL-784 free base is a selective matrix metalloproteinases (MMP) inhibitor, with IC₅₀s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13, respectively ^[1] .

BPHA	MMP	Cancer
BPHA is a potent and orally active *MMP-2, MMP-9* and *MMP-14* inhibitor with IC₅₀s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC₅₀s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects ^[1].

CTS-1027 1 Publications Verification Ro 1130830; RS 130830	MMP	Cancer
CTS-1027 is a potent small molecule inhibitor of *MMPs, with IC₅₀s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1*.

MMP-9-IN-9	MMP	Neurological Disease Inflammation/Immunology
MMP-9-IN-9 (compound 4f) is a slective *MMP-9* inhibitor with an IC₅₀ of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects ^[1].

ABT-770	MMP	Cancer
ABT-770 (compound 11) is a highly selective and orally active *MMP* inhibitor, demonstrating over 1000-fold selectivity for *MMP-2* (IC₅₀=4 nM) compared to *MMP-1* (IC₅₀=4600 nM). ABT-770 can be utilized in studies related to tumor growth, invasion, and metastasis ^[1].

Cordycepin (Standard)	TNF Receptor MMP Bacterial Autophagy Antibiotic	Infection Inflammation/Immunology Cancer
Cordycepin (Standard) is the analytical standard of Cordycepin. This product is intended for research and analytical applications. Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner ^[1]. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .

MMPI-1154	MMP	Cardiovascular Disease
MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) *MMP-2* inhibitor(IC₅₀=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC₅₀s of 1.8 μM,10 μM, and 13 μM, respectively ^[1].

MMP Inhibitor II	MMP	Cancer
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC₅₀ values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively ^[1].

Actinonin 5 Publications Verification (-)-Actinonin	Aminopeptidase Bacterial MMP Apoptosis Antibiotic	Infection Cancer
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K_i of 0.28 nM. Actinonin also inhibits *MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α* with K_i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities ^[1] .

Luteolin 7-O-glucuronide (Standard)	MMP	Neurological Disease Inflammation/Immunology
Luteolin 7-O-glucuronide (Standard) is the analytical standard of Luteolin 7-O-glucuronide. This product is intended for research and analytical applications. Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC₅₀s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively ^[1].

Prinomastat 2 Publications Verification AG3340; KB-R9896	MMP Apoptosis	Cancer
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC₅₀s of 79, 6.3 and 5.0 nM for *MMP-1, MMP-3* and *MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13* and *MMP-9* with K_is of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity ^[1] .

Cat. No.	Product Name	Type

HY-W127716

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 1 Publications Verification	Fluorescent Dyes/Probes
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .

HY-P3098

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	Chromogenic Substrates
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity ^[1] .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	Fluorescent Dyes/Probes
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) ^[1] .

Cat. No.	Product Name	Type

HY-NP122

Highly purified Type I collagen, from porcine skin Porcine Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from porcine skin (Porcine Type I collagen, immunization grade) is an immune grade collagen derived from porcine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP127

Highly purified Type I collagen, from canine skin Canine Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from canine skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from canine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP107

Highly purified Type I collagen, from rat skin Rat Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from rat skin (Rat Type I collagen, immunization grade) is an immune grade collagen derived from rat skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP109

Highly purified type I collagen, from mouse skin Mouse Type I collagen, immunization grade	Native Proteins
Highly purified type I collagen, from mouse skin (Mouse Type I collagen, immunization grade) is an immune grade collagen derived from mouse skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP111

Highly purified Type V collagen, from mouse intestine Mouse Type V collagen, immunization grade	Native Proteins
Highly purified Type V collagen, from mouse intestine (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse intestine, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP112

Highly purified Type I collagen, from chick skin Chick type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from chick skin (Chick type I collagen, immunization grade) is an immune grade collagen derived from chick skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP118

Highly purified Type III collagen, from human placenta Human Type III collagen, immunization grade	Native Proteins
Highly purified Type III collagen, from human placenta (Human Type III collagen, immunization grade) is an immune grade collagen derived from human placenta, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP124

Highly purified Type III collagen, from porcine skin Porcine Type III collagen, immunization grade	Native Proteins
Highly purified Type III collagen, from porcine skin (Porcine Type III collagen, immunization grade) is an immune grade collagen derived from porcine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP128

Highly purified Type I collagen, from rabbit skin Rabbit Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from rabbit skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from rabbit skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP116

Highly purified Type I collagen, from human placenta Human Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from human placenta (Human Type I collagen, immunization grade) is an immune grade collagen derived from human placenta, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP103

Highly purified Type III collagen, from bovine skin Bovine Type III collagen, immunization grade	Native Proteins
Highly purified Type III collagen, from bovine skin (Bovine Type III collagen, immunization grade) is an immune grade collagen derived from bovine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP123

Highly purified Type II collagen, from porcine articular cartilage Porcine Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from porcine articular cartilage (Porcine Type II collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP126

Highly purified Type XI collagen, from porcine articular cartilage Porcine Type XI collagen, immunization grade	Native Proteins
Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP120

Highly purified Type V collagen, from human placenta Human Placenta Type V collagen, immunization grade	Native Proteins
Highly purified Type V collagen, from human placenta (Human Placenta Type V collagen, immunization grade) is an immune grade collagen derived from human placenta, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP113

Highly purified Type II collagen, from chick sternal cartilage Chick Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from chick sternal cartilage (Chick Type II collagen, immunization grade) is an immune grade collagen derived from chick sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP105

Highly purified Type IX collagen, from bovine articular cartilage Bovine Type IX collagen, immunization grade	Native Proteins
Highly purified Type IX collagen, from bovine articular cartilage (Bovine Type IX collagen, immunization grade) is an immune grade collagen derived from bovine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP108

Highly purified type II collagen, from rat sternal cartilage Rat Type II collagen, immunization grade	Native Proteins
Highly purified type II collagen, from rat sternal cartilage (Rat Type II collagen, immunization grade) is an immune grade collagen derived from rat sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP110

Highly purified Type II collagen, from mouse sternal cartilage Mouse Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from mouse sternal cartilage (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP114

Highly purified Type IX collagen, from chick articular cartilage Chick Type IX collagen, immunization grade	Native Proteins
Highly purified Type IX collagen, from chick articular cartilage (Chick Type IX collagen, immunization grade) is an immune grade collagen derived from chick articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP121

Highly purified Type XI collagen, from human sternal cartilage Human Type XI collagen, immunization grade	Native Proteins
Highly purified Type XI collagen, from human sternal cartilage (Human Type XI collagen, immunization grade) is an immune grade collagen derived from human sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP119

Highly purified Type V collagen, from human amnion Human Amnion Type V collagen, immunization grade	Native Proteins
Highly purified Type V collagen, from human amnion (Human Amnion Type V collagen, immunization grade) is an immune grade collagen derived from human amnion, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP125

Highly purified Type IX collagen, from porcine articular cartilage Porcine Type IX collagen, immunization grade	Native Proteins
Highly purified Type IX collagen, from porcine articular cartilage (Porcine Type IX collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP129

Highly purified Type II collagen, from sheep articular cartilage Sheep Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from sheep articular cartilage (Sheep Type II collagen, immunization grade) is an immune grade collagen derived from sheep articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP130

Highly purified Type II collagen, from goat articular cartilage Goat Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from goat articular cartilage (Goat Type II collagen, immunization grade) is an immune grade collagen derived from goat articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP117

Highly purified Type II collagen, from human sternal cartilage Human Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from human sternal cartilage (Human Type II collagen, immunization grade) is an immune grade collagen derived from human sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP104

Highly purified Type V collagen, from bovine amnion Bovine Amnion Type V collagen, immunization grade	Native Proteins
Highly purified Type V collagen, from bovine amnion (Bovine Amnion Type V collagen, immunization grade) is an immune grade collagen derived from bovine amnion, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP106

Highly purified Type XI collagen, from bovine articular cartilage Bovine Type XI collagen, immunization grade	Native Proteins
Highly purified Type XI collagen, from bovine articular cartilage (Bovine Type XI collagen, immunization grade) is an immune grade collagen derived from bovine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP115

Highly purified Type XI collagen, from chick articular cartilage Chick Type XI collagen, immunization grade	Native Proteins
Highly purified Type XI collagen, from chick articular cartilage (Chick Type XI collagen, immunization grade) is an immune grade collagen derived from chick articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

Cat. No.	Product Name	Target	Research Area

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 ^[1]. (Ex/Em=325 nm/400 nm)

HY-118060

Dipeptide 2 N-Valyltryptophan; Val-Trp	Peptides	Others
Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient ^[1].

HY-P10043

MMP-1 Substrate	Peptides	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity ^[1].

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 ^[1].Ex/Em = 340/440 nm

HY-P4574

VPLSLYSG	MMP	Others
VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), *MMP-1* and *MMP-2. VPLSLYSG has potential applications in MMP* substrates ^[1] .

HY-P3098

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	MMP	Others
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity ^[1] .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) ^[1] .

HY-P2608

DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH	Fluorescent Dye	Others
DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a K_m of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity ^[1].

HY-P5224

Lipospondin	Peptides	Others
Lipospondin is a bioactive peptide with anti-wrinkl effect and has been reported used as a cosmetic ingredient ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P99590

Sotatercept ACE-011	TGF-β Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions ^[1] .

Recombinant Proteins Recommended:

MMP-1

Species:	Human (3)
Tag:	His (3) SUMO (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70250

	MMP-1 Protein, Human (HEK293, His) rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293
	The MMP-1 protein acts as an enzyme capable of cleaving types I, II, and III collagen at specific sites within the helical domain. In addition, it exhibits lytic activity against type VII and type X collagen. MMP-1 Protein, Human (HEK293, His) is the recombinant human-derived MMP-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MMP-1 Protein, Human (HEK293, His) is 450 a.a., with molecular weight of 49-61 kDa.

HY-P70250A

	MMP-1 Protein, Human (HEK293, C-His) rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293

HY-P700007

	MMP-14 Protein, Human (His-SUMO) Matrix metalloproteinase 14 ; Matrix metalloproteinase-14; Membrane type 1 matrix metalloproteinase ; Membrane type 1 metalloprotease; Membrane type matrix metalloproteinase 1; Membrane-type-1 matrix metalloproteinase; MMP 14; MMP X1; MMP-14; MMP-X1; MMP14; MMP14_HUMAN; MMPX1; MT MMP 1	Human	E. coli
	MMP-14 protein is an endopeptidase that degrades collagen and activates progelatinase A. MMP-14 Protein, Human (His-SUMO) is the recombinant human-derived MMP-14 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of MMP-14 Protein, Human (His-SUMO) is 471 a.a., with molecular weight of ~69.9 KDa.

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Cat. No.	Product Name	Chemical Structure

HY-N1981S1

Triolein-d5
Triolein-d₅ is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].

HY-N1981S

Triolein-13C3
Triolein- ¹³C₃ is the ¹³C-labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80754

	MMP1 Antibody MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1	WB, IP	Human
	MMP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 54 kDa, targeting to MMP1. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80754A

	MMP1 Antibody(YA3394) MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1	WB, FC, ICC/IF, IHC-P	Human
	MMP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to MMP1. It can be used for WB,FC,ICC/IF,IHC-P assays with tag free, in the background of Human.

HY-P81845

	MMP14 Antibody (YA1590) MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1	WB, IHC-P, IP	Human, Hamster
	MMP14 Antibody (YA1590) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1590), targeting MMP14, with a predicted molecular weight of 66 kDa (observed band size: 66 kDa). MMP14 Antibody (YA1590) can be used for WB, IHC-P, IP experiment in human, hamster background.

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Cat. No.	Product Name		Classification

HY-RS08516

MMP1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS08517

Mmp1 Rat Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
Mmp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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MMP-1

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