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Results for "

Mushroom

" in MedChemExpress (MCE) Product Catalog:

58

Inhibitors & Agonists

2

Biochemical Assay Reagents

4

Peptides

35

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N13243
    Reishi Mushroom Extract

    		Others Others
    Reishi Mushroom Extract is the extract of Reishi Mushroom, with content of 10% -50% Polysaccharide.
    Reishi Mushroom Extract
  • HY-114866
    Eritadenine

    Lentinacin; D-Eritadenine; Lentysine

    		 Biochemical Assay Reagents Cardiovascular Disease
    Eritadenine (Lentinacin) is a S-adenosyl-L-homocysteine hydrolase (SAHH) inhibitor. Eritadenine can be found in secondary metabolites of shiitake mushrooms. Eritadenine lowers blood cholesterol levels and can be used in cardiovascular disease research .
    Eritadenine
  • HY-W013571
    4-Isopropylbenzoic acid

    Cuminic acid

    		 Fungal Infection
    4-Isopropylbenzoic acid, an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase .
    4-Isopropylbenzoic acid
  • HY-125449
    Fasciculic acid C

    		Calmodulin Others
    Fasciculic acid C is a calmodulin antagonist that can be isolated from mushroom Naematoloma fasciculare .
    Fasciculic acid C
  • HY-161289
    Tyrosinase-IN-24

    		Tyrosinase Cancer
    Tyrosinase-IN-24 (compound 3b) is a tyrosinase inhibitor with inhibitory activity against mushroom tyrosinase .
    Tyrosinase-IN-24
  • HY-121111
    Agaritine

    		Others Cancer
    Agaritine is a compound isolated from the commonly cultivated commercial mushroom Agaricus bisporus. Agaritine is hydrolyzed by an enzyme system present in the mushroom into 4-(hydroxymethyl)benzenediazonium ion, which is a carcinogen in mice. Agaritine is structurally similar to some known carcinogens and can be used for research in cancer and food safety .
    Agaritine
  • HY-N10286
    Chetoseminudin B

    		Tyrosinase Others
    Chetoseminudin B possesses mushroom tyrosinase inhibitory activity with IC50 of 31.7 μM .
    Chetoseminudin B
  • HY-N10285
    Phaeosphaone D

    		Tyrosinase Infection
    Phaeosphaone D is a thiodiketopiperazine alkaloid compound isolated from Phaeosphaeria fuckelii, an endophytic fungus. Phaeosphaone D displays mushroom tyrosinase inhibitory activity with an IC50 value of 33.2 μM .
    Phaeosphaone D
  • HY-122933
    Kurarinol

    		Tyrosinase Apoptosis Cardiovascular Disease Cancer
    Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase .
    Kurarinol
  • HY-141555
    5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione

    		Phosphodiesterase (PDE) Tyrosinase Others
    5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC50 of 429 and 467 μM. 5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione inhibits mushroom tyrosinase weakly, with Ki of 1.9 μM .
    5,5′-(1,3-Propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione
  • HY-125586
    β-Amanitin

    		DNA/RNA Synthesis ADC Cytotoxin Cancer
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
    β-Amanitin
  • HY-125860
    Tyrosinase, Mushroom

    Polyphenol oxidase

    		 Tyrosinase Metabolic Disease
    Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin and is encoded by TYR gene. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes .
    Tyrosinase, Mushroom
  • HY-131081
    γ-Amanitin

    		DNA/RNA Synthesis ADC Cytotoxin Cancer
    γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin and β-Amanitin. γ-Amanitin competitively binds to monoclonal antibody (mAb), with an IC50 of 163.1 ng/mL .
    γ-Amanitin
  • HY-P0096
    Decapeptide-12

    		Tyrosinase Sirtuin Inflammation/Immunology Endocrinology
    Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
    Decapeptide-12
  • HY-P2031
    Phallacidin

    		Arp2/3 Complex Others
    Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
    Phallacidin
  • HY-N9527
    Poricoic acid BM

    		Others Others
    Poricoic acid BM is a lanostane triterpenoid that can be found in from peels of the mushroom Wolfiporia cocos .
    Poricoic acid BM
  • HY-N10287
    Leptosin D

    		Tyrosinase Infection
    Leptosin D, a thiodiketopiperazine alkaloid, is a mushroom tyrosinase inhibitor, with an IC50 of 28.4 μM .
    Leptosin D
  • HY-P0028
    Phalloidin
    10+ Cited Publications

    		 Fluorescent Dye Others
    Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .
    Phalloidin
  • HY-131327
    Azo-resveratrol

    		Tyrosinase Cancer
    Azo-resveratrol, an Azo compound, inhibits Mushroom tyrosinase (IC50=36.28 μM).
    Azo-resveratrol
  • HY-N9271
    Grifolin
    1 Publications Verification

    		 Apoptosis Cancer
    Grifolin is an antineoplastic agent can be isolated from the mushroom Albatrellus confluens and significantly induces apoptosis .
    Grifolin
  • HY-149157
    L-Lysine orotate

    		Others Metabolic Disease
    L-Lysine orotate is a salt of L-lysine and orotic acid that can potentiate the toxicity of an extract of the mushroom Amanita phalloides .
    L-Lysine orotate
  • HY-N12810
    Sanggenon O

    		Tyrosinase Others
    Sanggenon O is a mushroom tyrosinase inhibitor that can be isolated from Morus nigra, with an IC50 value of 1.15 μM .
    Sanggenon O
  • HY-19610
    α-Amanitin
    Maximum Cited Publications
    34 Publications Verification

    α-Amatoxin

    		 DNA/RNA Synthesis ADC Cytotoxin Cancer
    α-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.
    α-Amanitin
  • HY-131083
    ε-Amanitin

    		DNA/RNA Synthesis ADC Cytotoxin Cancer
    ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II .
    ε-Amanitin
  • HY-129468
    Pirimiphos ethyl

    		Cholinesterase (ChE) Neurological Disease
    Pirimiphos ethyl is a kind of organophosphorus pesticide that commonly employes for the protection of crops including vegetables, bananas, turf and mushrooms through the inhibition of acetylcholinesterase activity .
    Pirimiphos ethyl
  • HY-N3266
    Methyl rosmarinate

    		Tyrosinase Cancer
    Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase .
    Methyl rosmarinate
  • HY-121889
    FQ

    		Tyrosinase Inflammation/Immunology
    FQ is a tyrosinase inhibitor that effectively inhibits the diphenolase activity of mushroom tyrosinase (IC50=120 μM). FQ can be used in the study of pigmentation .
    FQ
  • HY-W127366
    7-Octen-1-ol

    		Biochemical Assay Reagents Others
    7-Octen-1-ol is an organic compound belonging to the group of alcohols. It has a strong mushroom-like smell and is commonly found in a variety of foods, such as mushrooms, soybeans, and peanuts. 7-Octen-1-ol has various applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfumes, colognes and air fresheners. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    7-Octen-1-ol
  • HY-117761
    MHY908

    		PPAR Metabolic Disease Cancer
    MHY908 is a potent dual agonist of PPARα and PPARγ . MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity .
    MHY908
  • HY-N3977
    Grifolic acid

    		Free Fatty Acid Receptor Inflammation/Immunology
    Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120) .
    Grifolic acid
  • HY-120243
    L-Ibotenic acid

    		Others Neurological Disease
    L-Ibotenic acid is a naturally occurring psychoactive compound found in Amanita muscaria and similar mushroom species, predominantly located in the temperate and boreal regions of the northern hemisphere, known for its conformationally restricted structure.
    L-Ibotenic acid
  • HY-159586
    Tyrosinase-IN-32

    		Tyrosinase Cancer
    Tyrosinase-IN-32 (compound 11) is a hydroxamate-based alkaloid and a mushroom tyrosinase inhibitor. Tyrosinase-IN-32 has antioxidant activity and can be isolated from black pepper (Piper nigrum L.) .
    Tyrosinase-IN-32
  • HY-122493
    Illudin M

    		DNA Alkylator/Crosslinker Apoptosis Cancer
    Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities .
    Illudin M
  • HY-161950
    Tyrosinase-IN-33

    		Tyrosinase Metabolic Disease
    Tyrosinase-IN-33 (compound 5) a Pyridine-based compound, is a potent inhibitor of mushroom tyrosinase diphenolase activity. Tyrosinase-IN-33 significantly decreases the enzyme activity, with an IC50 of 9.0 μM .
    Tyrosinase-IN-33
  • HY-N7842
    17-Methylstearic acid

    17-Methylstearic acid; 17-Methyloctadecanoic acid

    		 Biochemical Assay Reagents Others
    17-Methylstearic acid is a methyl-branched fatty acid that has been found in mouse meibomian glands, C. cornucopioides mushrooms, and Phytobacter species. It is also found in the aerial parts of C. ladanifer, where its concentration varies seasonally.
    17-Methylstearic acid
  • HY-121578
    Agaridoxin

    GDHB

    		 Adrenergic Receptor Neurological Disease
    Agaridoxin (GDHB) is a blocker of catecholamine and adrenergic alpha-type receptors isolated from mushrooms. Agaridoxin activates adenylyl cyclase in rat hypothalamic membrane granules in the presence of guanosyl imide diphosphate (Gpp(NH)p) .
    Agaridoxin
  • HY-W015616
    Benzylacetone

    4-Penylbutan-2-one

    		 Tyrosinase Metabolic Disease
    Benzylacetone is an aromatic compound from agarwood . Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity， with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively . Benzylacetone has appetite-enhancing and locomotor-reducing effects .
    Benzylacetone
  • HY-N10219
    Dihydroaltenuene B

    		Tyrosinase Fungal Infection
    Dihydroaltenuene B is a potent mushroom tyrosinase inhibitor with an IC50 of 38.33 µM. Dihydroaltenuene B shows the hydrogen bonding interactions between the 3-OH and 4’-OH and the His244, Met280 and Gly281 residues of tyrosinase .
    Dihydroaltenuene B
  • HY-N7302
    Anthracophyllone

    		Others Cancer
    Anthracophyllone is an aristolane sesquiterpene that can be isolated from the mushroom Anthracophyllum. Anthracophyllone has cytotoxicity against MCF-7, KB, NCI-H187, Vero cells (IC50: 32.97, 18.02, 15.17, 18.06 μM) .
    Anthracophyllone
  • HY-N11893
    8-C-Glucosyl-(R)-aloesol

    (R)-Aloesinol

    		 Others Others
    8-C-Glucosyl-(R)-aloesol ((R)-Aloesinol) is a bioactive chromone analogue .
    8-C-Glucosyl-(R)-aloesol
  • HY-N2101
    Benzoyloxypaeoniflorin

    		Tyrosinase NF-κB Inflammation/Immunology
    Benzoyloxypaeoniflorin, isolated from the root of Paeonia suffruticosa, is a tyrosinase inhibitor against mushroom tyrosinase with IC50 of 0.453 mM. Benzoyloxypaeoniflorin is NF-κB Inhibitor and contributes to improving blood circulation through its inhibitory effect on both platelet aggregation and blood coagulation .
    Benzoyloxypaeoniflorin
  • HY-N2006
    Ganoderic acid B

    		EBV HIV Protease Infection Inflammation/Immunology
    Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
    Ganoderic acid B
  • HY-19893
    Antroquinonol

    (+)-Antroquinonol

    		 Keap1-Nrf2 Inflammation/Immunology Cancer
    Antroquinonol ((+)-Antroquinonol), a ubiquinone derivative from the mushroom Antrodia camphorata, has hepatoprotective, anti-inflammatory, and anti-cancer effects . Antroquinonol can be used for the research of colon cancer . Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice .
    Antroquinonol
  • HY-118341
    Clitocine

    		Apoptosis Bcl-2 Family Cancer
    Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity .
    Clitocine
  • HY-N9283
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran

    		Reactive Oxygen Species Neurological Disease Cancer
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC50 of 28 μM, inhibits malondialdehyde (MDA) with the IC50 of 71 μM, and inhibits α-glucosidase with the IC50 of 6.22 μM .
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran
  • HY-101258
    Cardol triene

    		Parasite Infection
    Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50=22.5 μM). It is schistosomicidal, killing 25, 75, and 100% of S. mansoni worms after 24 hours when used at concentrations of 50, 100, or 200 μM, respectively. It has been used as a starting material for the synthesis of bis-benzoxazines.
    Cardol triene
  • HY-N2006R
    Ganoderic acid B (Standard)

    		EBV HIV Protease Infection Inflammation/Immunology
    Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
    Ganoderic acid B (Standard)
  • HY-N1430
    Oxyresveratrol

    trans-Oxyresveratrol

    		 Tyrosinase HSV Autophagy Others
    Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects .
    Oxyresveratrol
  • HY-N0619
    Mulberroside A
    3 Publications Verification

    		 TNF Receptor Interleukin Related Tyrosinase Inflammation/Immunology
    Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.) . Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects . Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM .
    Mulberroside A
  • HY-N7135
    Tropolone

    		Tyrosinase Fungal Metabolic Disease Inflammation/Immunology Cancer
    Tropolone is a seven-membered non-benzenoid aromatic compound, which is the precursor of many Azulene derivatives. Tropolone is a potent mushroom tyrosinase inhibitor with an IC50 value of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU 2+ Reversa. Tropolone exhibits broad anti-viral and anti-fungal activity and is synergistic upon co-treatment with nucleos(t)ide analog drugs. Tropolone is a promising candidate for research in osteosarcoma .
    Tropolone

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