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Neuraminidase inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (2) Antibiotic (5) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (1) Carboxylesterase (2) Drug Metabolite (3) Endogenous Metabolite (2) ERK (2) IKK (2) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (71) Interleukin Related (1) Isotope-Labeled Compounds (4) JNK (2) MicroRNA (1) P2X Receptor (1) p38 MAPK (2) STAT (2) TNF Receptor (1) Topoisomerase (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Infection (68) Inflammation/Immunology (13) Metabolic Disease (2) Neurological Disease (5)
Click Chemistry:	Azide (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137334

Neuraminidase-IN-1	Influenza Virus	Infection
Neuraminidase-IN-1 is a *neuraminidase* inhibitor, with an IC₅₀ of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus .

HY-163521

Neuraminidase-IN-19	Influenza Virus	Cancer
Neuraminidase-IN-19 (compound 5n) is an inhibitor (IC₅₀: 0.13 μM) of neuraminidase with a thiophene ring (neuraminidase) and has anticancer activity .

HY-149060

Neuraminidase-IN-15	Influenza Virus	Infection
Neuraminidase-IN-15 is an inhibitor of *neuraminidase. Neuraminidase-IN-15 inhibits* the activity of La Sota Clone 30 NDV-HN with an IC₅₀ value of 0.06 µM. Neuraminidase-IN-15 can be used for the study of Newcastle disease virus (NDV) .

HY-149059

Neuraminidase-IN-14	Influenza Virus	Infection
Neuraminidase-IN-14 is an inhibitor of *neuraminidase. Neuraminidase-IN-14 inhibits* the activity of La Sota Clone 30 NDV-HN with an IC₅₀ value of 0.20 µM. Neuraminidase-IN-14 can be used for research on Newcastle disease virus (NDV) infection .

HY-144420

Neuraminidase-IN-5	Influenza Virus	Infection
Neuraminidase-IN-5 (Compound 5b) is a potent inhibitor of *neuraminidase* with an IC₅₀ of 0.02 μM. Neuraminidase (NA) is a promising target for development of anti-influenza agents. Neuraminidase-IN-5 is a dihydrofurocoumarin derivative compound .

HY-163392

Neuraminidase-IN-17	Influenza Virus	Infection
Neuraminidase-IN-17 (compound N10) is a *neuraminidase* inhibitor with the EC₅₀ of 0.11 μM. Neuraminidase-IN-17 shows antiviral activity in vitro .

HY-143488

Neuraminidase-IN-8	Influenza Virus	Infection
Neuraminidase-IN-8 (Compound 6d) is a potent *neuraminidase* inhibitor with an IC₅₀ of 0.027 µM. Neuraminidase-IN-8 shows anti-influenza activities .

HY-129666

NSC-65847	Influenza Virus	Neurological Disease
NSC-65847 is a groundbreaking dual inhibitor targeting both viral neuraminidase and Streptococcus pneumoniae neuraminidase.

HY-162801

Neuraminidase-IN-21	Influenza Virus	Infection
Neuraminidase-IN-21 (Compound 6d) is an influenza H1N1 virus Neuraminidase inhibitor, with IC₅₀s of 0.30 µM for Neuraminidase, and 30.01 µM for H1N1 strain of influenza. Neuraminidase-IN-21 formsg three hydrogen bonds with Arg292, Arg371, and Tyr406 of Neuraminidase .

HY-144426

Neuraminidase-IN-6	Influenza Virus	Infection
Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of *neuraminidase* with an IC₅₀ of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents .

HY-161983

Neuraminidase-IN-22	Influenza Virus	Infection
Neuraminidase-IN-22 (compound 3e) is a potent, selective and orally active *neuraminidase* inhibitor with an IC₅₀ value of 0.03 µM. Neuraminidase shows cytotoxicity and anti-influenza A virus activity .

HY-144103

Neuraminidase-IN-4	Influenza Virus	Infection
Neuraminidase-IN-4 (Compound 4b) is a potent inhibitor of *neuraminidase* with an EC₅₀ of 1.59 μM. Neuraminidase (NA) is an important target for the research of influenza. Neuraminidase-IN-4 exhibits excellent antiviral activity against A/chicken/Hubei/327/2004 (H5N1-DW) .

HY-151103

Neuraminidase-IN-10	Influenza Virus	Infection
Neuraminidase-IN-10 is a potent neuraminidase (NA) inhibitor with anti-influenza activity. Neuraminidase-IN-10 is against H1N1, H5N1, and H5N8 with IC₅₀ values of 2.6 nM, 5.1 nM, and 1.65 nM, respectively .

HY-163522

Neuraminidase-IN-20	Influenza Virus	Infection
Neuraminidase-IN-20 (Compound 5i) is a potent inhibitor of mutant neuraminidase (NA) (H5N1-H274Y) (IC₅₀= 0.44 μM).Neuraminidase-IN-20 binds to the 430 cavity site of NA and disrupts the enzymatic activity of NA .

HY-149058

Neuraminidase-IN-13	Influenza Virus	Infection
Neuraminidase-IN-13 (Compound 10) is a *neuraminidase* inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells . Neuraminidase-IN-13 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-163393

Neuraminidase-IN-18	Influenza Virus	Infection
Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor. Neuraminidase-IN-18 shows potency in inhibition of H5N1 NA with an IC₅₀ of 0.14 μM and 0.27 μM against the wild-type H5N1 NA and H5N1-H274Y mutant NA, respectively. Neuraminidase-IN-18 inhibits influenza virus replication by binding to NAs in cell level .

HY-129150

Ganoderic acid TR	Influenza Virus	Infection
Ganoderic acid TR is a broad-spectrum inhibitor against *influenza neuraminidases* (NAs)*, particularly H5N1 and H1N1 neuraminidases. The IC₅₀* values of 10.9 and 4.6 μM, respectively .

HY-17016

Oseltamivir phosphate 30+ Cited Publications GS 4104 phosphate	Influenza Virus	Infection Cancer
Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-N10298

Massarilactone H	Influenza Virus	Infection
Massarilactone H, a polyketide, is a *neuraminidase* inhibitor, with an IC₅₀ of 8.18 µM .

HY-N0243

Theaflavin 3 Publications Verification	Influenza Virus Endogenous Metabolite	Infection
Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

HY-117151

A-315675	Influenza Virus	Inflammation/Immunology
A-315675 is a potent highly potent inhibitor of A and B strain influenza virus neuraminidases inhibitor .

HY-146306

Neuraminidase-IN-9	Influenza Virus	Infection
Neuraminidase-IN-9 (Compound 6l) is a potent influenza *neuraminidase* inhibitor with IC₅₀ values of 0.12, 0.049 and 0.16 µM against H5N1, H5N2 and H5N6, respectively .

HY-151104

Neuraminidase-IN-11	Influenza Virus	Infection
Neuraminidase-IN-11 (15e) is a potent and selective neuraminidase (NA) inhibitor with the IC₅₀ values of 4.7 nM, 8.46 nM and 1.5 nM against H1N1, H5N1 and H5N8 NAs respectively .

HY-43575

Oseltamivir-acetate	Influenza Virus	Infection
Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B .

HY-N8399

Yadanziolide B	Influenza Virus	Infection Inflammation/Immunology
Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor .

HY-139991

Neuraminidase-IN-3	Influenza Virus	Infection
Neuraminidase-IN-3 (compound 23d) is a potent influenza neuraminidase (NA) inhibitor with IC₅₀ values of 0.73, 0.26, and 0.63 nM against H1N1, H5N1, and H5N8 NAs, respectively .

HY-13210

Zanamivir 10+ Cited Publications	Influenza Virus Antibiotic	Infection
Zanamivir is an influenza viral *neuraminidase* inhibitor with IC₅₀ values of 0.95 nM and 2.7 nM for influenza A and B, respectively.

HY-141862

Zanamivir-Cholesterol Conjugate	Influenza Virus	Infection
Zanamivir–cholesterol conjugate is a long-acting *neuraminidase* inhibitor with potent efficacy against drug-resistant influenza viruses.

HY-147331

Oseltamivir acid methyl ester	Antibiotic Carboxylesterase	Neurological Disease
Oseltamivir acid methyl ester is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid by carboxylesterase 1 (CES1) .

HY-147331A

Oseltamivir acid methyl ester hydrochloride	Antibiotic Carboxylesterase	Neurological Disease
Oseltamivir acid methyl ester hydrochloride is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester hydrochloride is converted to oseltamivir acid by carboxylesterase 1 (CES1) .

HY-W892911

AV-5080	Influenza Virus	Infection
AV-5080 is an orally active *neuraminidase* inhibitor. AV-5080 can be used for the research of influenza A and B viruses .

HY-149088

Neuraminidase-IN-16	Influenza Virus	Infection
Neuraminidase-IN-16 (Compound 43b) is a potent *neuraminidase* inhibitor with IC₅₀s of 0.031, 0.15, 0.25, 0.60, 0.63 and 10.08 μM against neuraminidase of H5N1, H5N8, H1N1, H3N2, H5N1-H274Y and H1N1-H274Y, respectively .

HY-17016S1

Oseltamivir-d3 phosphate GS 4104-d₃ phosphate	Isotope-Labeled Compounds Influenza Virus	Infection
Oseltamivir-d₃ (phosphate)eis the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-13210A

Zanamivir (hydrate)(5:1)	Antibiotic Influenza Virus	Infection
Zanamivir hydrate (5:1) is the hydrate of Zanamivir. Zanamivir is an influenza viral *neuraminidase* inhibitor with IC₅₀ values of 0.95 nM and 2.7 nM for influenza A and B, respectively .

HY-17016S

Oseltamivir-d5 phosphate GS 4104-d₅ phosphate	Isotope-Labeled Compounds Influenza Virus	Infection
Oseltamivir-d₅ (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].

HY-N9919

Glyasperin C	Others	Others
Glyasperin C is a potent and reversible noncompetitive inhibitor of *neuraminidase* with an IC₅₀ of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis .

HY-17016R

Oseltamivir (phosphate) (Standard) GS 4104 (phosphate) (Standard)	Influenza Virus	Infection
Oseltamivir (phosphate) (Standard) is the analytical standard of Oseltamivir (phosphate). This product is intended for research and analytical applications. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-N0243R

Theaflavin (Standard)	Influenza Virus Endogenous Metabolite	Infection
Theaflavin (Standard) is the analytical standard of Theaflavin. This product is intended for research and analytical applications. Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

HY-146004

Influenza A virus-IN-4	Influenza Virus	Infection
Influenza A virus-IN-4 (compound 23b), an Oseltamivir derivative, is a potent inhibitor of *neuraminidase*. Influenza A virus-IN-4 exerts powerful inhibitions on influenza viruses .

HY-163364

DS-22-inf-021	Influenza Virus	Infection
DS-22-inf-021 is a neuraminidase (NA) inhibitor. DS-22-inf-021 has antiviral activity against influenza viruses .

HY-13210R

Zanamivir (Standard)	Influenza Virus Antibiotic	Infection
Zanamivir (Standard) is the analytical standard of Zanamivir. This product is intended for research and analytical applications. Zanamivir is an influenza viral *neuraminidase* inhibitor with IC₅₀ values of 0.95 nM and 2.7 nM for influenza A and B, respectively.

HY-133172

Zanamivir amine	Biochemical Assay Reagents
Zanamivir amine is a neuraminidase inhibitor with antiviral activity. Zanamivir amine can effectively inhibit the proliferation of influenza virus. Zanamivir amine is clinically used to inhibit influenza infection. Zanamivir amine reduces viral load by interfering with the viral replication process.

HY-17015A

Peramivir 5+ Cited Publications RWJ-270201; BCX-1812	IKK JNK STAT p38 MAPK ERK	Infection Inflammation/Immunology
Peramivir is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19 .

HY-13318

Oseltamivir acid Maximum Cited Publications 56 Publications Verification GS 4071; Ro 64-0802; Oseltamivir carboxylate	Influenza Virus Drug Metabolite	Infection
Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of *influenza virus neuraminidase* (IC₅₀=2 nM)** with activity against both influenza A and B viruses .

HY-125798

2,3-Dehydro-2-deoxy-N-acetylneuraminic acid 2 Publications Verification Neu5Ac2en; DANA	Influenza Virus	Infection
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC₅₀s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .

HY-170445

Neuraminidase-IN-23	Influenza Virus	Infection Inflammation/Immunology
Neuraminidase-IN-23 (33c) is a potent neuraminidase (NA) inhibitor against influenza virus, with IC₅₀ values of 0.049 μM (H1N1), 0.26 μM (H3N2), 0.17 μM (H5N1), 0.013 μM (H5N8) and 0.74 μM (H5N1-H274Y), respectively .

HY-N2394

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Bacterial	Inflammation/Immunology
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive *bacterial neuraminidase* (BNA)** inhibitor with an IC₅₀ of 0.85 μM .

HY-17015

Peramivir trihydrate 5+ Cited Publications RWJ 270201 trihydrate; BCX 1812 trihydrate	Influenza Virus IKK JNK STAT p38 MAPK ERK	Infection Inflammation/Immunology
Peramivir trihydrate (RWJ-270201 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC₅₀ values ranging from 0.9 to 4.3 nM for nine NA subtypes .

HY-13318S

Oseltamivir acid-d3 Maximum Cited Publications 56 Publications Verification GS 4071-d₃; Ro 64-0802-d₃; Oseltamivir carboxylate-d₃	Influenza Virus	Infection
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-14818A

Laninamivir octanoate CS-8958	Influenza Virus	Infection
Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .

Cat. No.	Product Name	Type

HY-133172

Zanamivir amine	Cell Assay Reagents
Zanamivir amine is a neuraminidase inhibitor with antiviral activity. Zanamivir amine can effectively inhibit the proliferation of influenza virus. Zanamivir amine is clinically used to inhibit influenza infection. Zanamivir amine reduces viral load by interfering with the viral replication process.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-129150

Ganoderic acid TR	Infection Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Plants Disease Research Fields	Influenza Virus
Ganoderic acid TR is a broad-spectrum inhibitor against *influenza neuraminidases* (NAs)*, particularly H5N1 and H1N1 neuraminidases. The IC₅₀* values of 10.9 and 4.6 μM, respectively .

HY-N0243

Theaflavin 3 Publications Verification	Infection Structural Classification Flavonoids other families Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields	Influenza Virus Endogenous Metabolite
Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

HY-N9919

Glyasperin C	Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones	Others
Glyasperin C is a potent and reversible noncompetitive inhibitor of *neuraminidase* with an IC₅₀ of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis .

HY-N2394

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Quinones Structural Classification Rheum palmatum L. Classification of Application Fields Anthraquinones Polygonaceae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Bacterial
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive *bacterial neuraminidase* (BNA)** inhibitor with an IC₅₀ of 0.85 μM .

HY-N0736

Coptisine chloride Maximum Cited Publications 6 Publications Verification	Infection Alkaloids Structural Classification Classification of Application Fields Coptis chinensis Franch. Ranunculaceae Source classification Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields	Indoleamine 2,3-Dioxygenase (IDO) Bacterial Influenza Virus
Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a K_i value of 5.8 μM and an IC₅₀ value of 6.3 μM. Coptisine chloride is a potent *H1N1 neuraminidase* (NA-1)** inhibitor with an IC₅₀ of 104.6?μg/mL and can be used for influenza A (H1N1) infection.

HY-N2533

Cyanidin 3-sambubioside chloride Cyanidin-3-O-sambubioside chloride	Infection Structural Classification Anthocyans Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Influenza Virus Angiotensin-converting Enzyme (ACE)
Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC₅₀ of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties .

HY-N10298

Massarilactone H	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Influenza Virus
Massarilactone H, a polyketide, is a *neuraminidase* inhibitor, with an IC₅₀ of 8.18 µM .

HY-N8399

Yadanziolide B	Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Inflammation/Immunology Brucea javanica (L.) Merr.	Influenza Virus
Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor .

HY-N0243R

Theaflavin (Standard)	Structural Classification Flavonoids other families Flavanols Source classification Phenols Polyphenols Plants Endogenous metabolite	Influenza Virus Endogenous Metabolite
Theaflavin (Standard) is the analytical standard of Theaflavin. This product is intended for research and analytical applications. Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

HY-N3421

Koaburaside	Structural Classification Eucommia ulmoides Oliver Source classification Eucommiaceae Plants Saccharides Monosaccharides	Interleukin Related TNF Receptor Influenza Virus
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

HY-N7922

Urolithin M5 Decarboxyellagic acid	Structural Classification Canarium album (Lour.) Rauesch. Source classification Phenols Polyphenols Plants Burseraceae	Influenza Virus
Urolithin M5 is a *neuraminidase* inhibitor that can be isolated from Ganlanye. Urolithin M5 has antiviral activity in vitro and in vivo by inhibiting the activity of viral NA. Urolithin M5 can increase the survival rate and improve pulmonary edema in pr8-infected mouse models. Urolithin M5 can be used in anti-influenza research .

HY-N0736R

Coptisine chloride (Standard)	Alkaloids Structural Classification Coptis chinensis Franch. Ranunculaceae Source classification Plants Isoquinoline Alkaloids	Indoleamine 2,3-Dioxygenase (IDO) Bacterial Influenza Virus
Coptisine (chloride) (Standard) is the analytical standard of Coptisine (chloride). This product is intended for research and analytical applications. Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC₅₀ value of 6.3 μM. Coptisine chloride is a potent H1N1 neuraminidase (NA-1) inhibitor with an IC₅₀ of 104.6 μg/mL and can be used for influenza A (H1N1) infection.

HY-N2533R

Cyanidin 3-sambubioside (chloride) (Standard)	Structural Classification Anthocyans Flavonoids other families Source classification Phenols Polyphenols Plants	Influenza Virus Angiotensin-converting Enzyme (ACE)
Cyanidin 3-sambubioside (chloride) (Standard) is the analytical standard of Cyanidin 3-sambubioside (chloride). This product is intended for research and analytical applications. Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties .

HY-N10843

4-O-Methylepisappanol	Structural Classification Flavanonols Flavonoids Source classification Caesalpiniaceae Plants	Influenza Virus
4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC₅₀ values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .

HY-N2735

7,3',4'-Trihydroxy-3-benzyl-2H-chromene	Structural Classification Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Plants	Influenza Virus
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC₅₀ values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .

Cat. No.	Product Name	Chemical Structure

HY-13318S

Oseltamivir acid-d3 55+ Cited Publications
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-13317S

Oseltamivir-d3
Oseltamivir-d₃ is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1].

HY-17016S1

Oseltamivir-d3 phosphate
Oseltamivir-d₃ (phosphate)eis the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

HY-17016S

Oseltamivir-d5 phosphate
Oseltamivir-d₅ (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].

HY-13317S1

Oseltamivir-d3-1
Oseltamivir-d₃-1 is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].

HY-13317S3

Oseltamivir-d5
Oseltamivir-d₅ is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50 of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].

HY-13317S4

Oseltamivir-d3 hydrochloride
Oseltamivir-d₃ hydrochloride is the deuterium-labeled Oseltamivir (HY-13317) . Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC₅₀s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent .

HY-13318S1

Oseltamivir acid-13C,d3
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections .

Cat. No.	Product Name		Classification

HY-149058

Neuraminidase-IN-13		Azide
Neuraminidase-IN-13 (Compound 10) is a *neuraminidase* inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells . Neuraminidase-IN-13 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-149057

Neuraminidase-IN-12		Azide
NDV-IN-1 is an antiviral agent with high *neuraminidase* inhibitory activity. NDV-IN-1 exhibits in vitro inhibitory activity against Newcastle disease virus (NDV). NDV-IN-1 significantly inhibits NDV infection of Vero cells by preventing the release of virus particles from infected cells . Neuraminidase-IN-12 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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Neuraminidase inhibitor

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

Click Chemistry

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