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Results for "

Penicillium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (11) Apoptosis (7) Autophagy (3) Bacterial (12) Bcl-2 Family (1) c-Met/HGFR (1) Calcium Channel (1) Caspase (1) Cholinesterase (ChE) (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Endogenous Metabolite (10) ERK (1) Farnesyl Transferase (1) Fungal (15) Glucosidase (1) Glutathione S-transferase (1) HSV (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (2) Lipoxygenase (1) MEK (1) Microtubule/Tubulin (1) MMP (1) Na+/K+ ATPase (1) Neurokinin Receptor (1) Opioid Receptor (3) P-glycoprotein (1) p38 MAPK (1) Parasite (3) Phosphatase (1) Potassium Channel (3) Reactive Oxygen Species (2) SOD (1) Tyrosinase (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (1) Endocrinology (1) Infection (41) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (9)

By Targets:

Antibiotic (11)

Apoptosis (7)

Autophagy (3)

Bacterial (12)

Bcl-2 Family (1)

c-Met/HGFR (1)

Calcium Channel (1)

Caspase (1)

Cholinesterase (ChE) (1)

Cytochrome P450 (1)

DNA/RNA Synthesis (1)

Endogenous Metabolite (10)

ERK (1)

Farnesyl Transferase (1)

Fungal (15)

Glucosidase (1)

Glutathione S-transferase (1)

HSV (1)

Influenza Virus (1)

Interleukin Related (1)

Isotope-Labeled Compounds (2)

Lipoxygenase (1)

MEK (1)

Microtubule/Tubulin (1)

MMP (1)

Na+/K+ ATPase (1)

Neurokinin Receptor (1)

Opioid Receptor (3)

P-glycoprotein (1)

p38 MAPK (1)

Parasite (3)

Phosphatase (1)

Potassium Channel (3)

Reactive Oxygen Species (2)

SOD (1)

Tyrosinase (1)

By Research Areas:

Cancer (17)

Cardiovascular Disease (1)

Endocrinology (1)

Infection (41)

Inflammation/Immunology (4)

Metabolic Disease (1)

Neurological Disease (9)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120551

Fructigenine A	Others	Others
Fructigenine A (compound 4) is a active product that can be isolated from marine-derived Penicillium sp. .

HY-N12184

Peniciside	Others	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

HY-129591

Paraherquamide A PNU-97333	Others	Others
Paraherquamide A (PNU-97333) is a toxic metabolite that can be isolated from Penicillium paraherquei .

HY-N12904

Communesin B (+)-Communesin B; Nomofungin	Others	Cancer
Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium .

HY-N12911

Tanzawaic acid E	Others	Others
Tanzawaic acid E is a carboxylic acid and can be isolated from Penicillium steckii .

HY-126697

Eremofortin A	Endogenous Metabolite	Others
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

HY-122398

Janthitrem B	Others	Neurological Disease
Janthitrem B is a metabolite of Penicillium janthinellum that can induce tremorgenic in mice .

HY-126484

Eremofortin B	Others	Others
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

HY-116479

Citromycetin	Others	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-N12266

12-Hydroxyalbrassitriol	Others	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-129279

Andrastin A	Farnesyl Transferase	Cancer
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species .

HY-N7480A

Quinolactacin A1	Cholinesterase (ChE)	Neurological Disease
Quinolactacin A1 is a potent acetylcholinesterase (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

HY-P3043

Bilaid A	Opioid Receptor	Neurological Disease
Bilaid A is a μ-opioid receptor agonist that can be extracted from Penicillium. The K_i value is 3.1 μM. Bilaid A can be used in pain research .

HY-N12914

Tanzawaic acid B (+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E	Reactive Oxygen Species	Others
Tanzawaic acid B ((+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E) is a superoxide anion production inhibitor and can be isolated from Penicillium citrinum .

HY-126604

Pyranonigrin A	Others	Infection
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-129806

Rugulosin (+)-Rugulosin	Bacterial Fungal	Infection
Rugulosin is a crystalline colouring matter of Penicillium rugulosum Thom. Rugulosin shows markedly specific antibacterial activity and moderately antifungal activity .

HY-N8287

Oxaline	Microtubule/Tubulin	Cancer
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-122076

A-26771B	Antibiotic Bacterial Fungal	Infection
A-26771B is an antibiotic can be obtained from Penicillium turbatum. A-26771B exhibits moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. A-26771B also inhibits potassium-dependent ATPase in rat liver mitochondria .

HY-W099579

Kojic acid dipalmitate Kojic dipalmitate	Tyrosinase	Endocrinology
Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-N6748

Roquefortine C 1 Publications Verification	P-glycoprotein Cytochrome P450 Bacterial Endogenous Metabolite	Infection Cancer
Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria .

HY-N12761

Penpaxilloids A	Phosphatase Glucosidase	Metabolic Disease Inflammation/Immunology
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Others	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

HY-118463

Benzomalvin A	Neurokinin Receptor	Neurological Disease
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with K_i values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-P5591

PAF26	Fungal	Infection
PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .

HY-N10215

Canadensolide	Fungal Endogenous Metabolite	Infection
Canadensolide is an antifungal metabolite of Penicillium canadense.

HY-136871

Decarestrictin A1	Others	Infection
Decarestrictine A1 is a fungal metabolite that has been found in Penicillium.

HY-N8548

Fellutanine A	Endogenous Metabolite	Infection
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-N7221

Janthitrem G	Fungal	Infection
Janthitrem G is a microbial metabolite that can be isolated from cultures of Penicillium .

HY-125298

Cycloaspeptide A	Parasite	Infection
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .

HY-N11955

Cyclo(Ile-Leu)	Others	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-129208

Viridicatumtoxin	Antibiotic Fungal	Infection
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

HY-123474

PF-1163B	Fungal Antibiotic	Infection
PF-1163B is an antifungal antibiotic .

HY-E70111

Endo-1,5-α-arabinanase Endo-1,5-arabinanase	Others	Others
Endo-1,5-α-arabinanase (Endo-1,5-arabinanase) belongs to CAZy family 43 of the glycoside hydrolase (GH). Endo-1,5-α-arabinanase mainly shorts arabinooligosaccharides and arabinose from debranched arabinan .

HY-120154

Palitantin (±)-Palitantin	Parasite Endogenous Metabolite	Infection
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-N10220

Paraherquamide E	Endogenous Metabolite Parasite	Infection
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-125546

Erythromycin C	Antibiotic	Infection
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .

HY-121163

PF-184563	Fungal	Infection
Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease.

HY-N7222

Janthitrem F	Fungal	Infection
Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease .

HY-N13086

Peniviridiol A	Others	Others
Peniviridiol A (compound4) is a viridin derivative that can be isolated from rhizosphere fungus Penicillium sp. SMU0102 .

HY-125060

Viridicatin	Antibiotic Endogenous Metabolite	Infection
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-129384

Rubratoxin B	Others	Cancer
Rubratoxin B is a hepatotoxic mycotoxin that can be found in Penicillium rubrum Stoll. Rubratoxin B shows antitumor activity .

HY-N10442

Herqueilenone A	Others	Others
Herqueilenone A is a benzoquinone-chromanon that can be found in the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729[1].

HY-122404

Xantocillin Xanthocillin X	MEK ERK Autophagy	Cancer
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway .

HY-124301

Penicolinate A	Bacterial	Infection
Penicolinate A is a picolinic acid derivative. Penicolinate A is isolated from endophytic Penicillium sp. BCC16054. Penicolinate A exhibits antimalarial and antitubercular activities .

HY-126983

6',7'-Epoxybergamottin Epoxybergamottin	Others Endogenous Metabolite	Others
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity .

HY-N8498

GKK1032B	Apoptosis	Cancer
GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation .

HY-N12169

Janthitrem A 11,12-Epoxyjanthitrem B	Others	Neurological Disease
Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae .

HY-116474

Viridicatol	Fungal	Infection
Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL .

Cat. No.	Product Name	Target	Research Area

HY-P3519A

ACV Tripeptide TFA	Peptides	Others
ACV Tripeptide TFA is the TFA form of ACV Tripeptide (HY-P3519). ACV Tripeptide TFA is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide TFA is synthesized by a large non-ribosomal peptide synthase called ACV synthase .

HY-P5941

Bilaid C1	Peptides	Others
Bilaid C1 is a tetrapeptide isolated from Penicillium sp .

HY-P3043

Bilaid A	Opioid Receptor	Neurological Disease
Bilaid A is a μ-opioid receptor agonist that can be extracted from Penicillium. The K_i value is 3.1 μM. Bilaid A can be used in pain research .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-P5591

PAF26	Fungal	Infection
PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .

HY-P4107

Bilaid C	Opioid Receptor	Neurological Disease
Bilaid C, a tetrapeptide, can be isolated from the Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid C is also a potent and selective μ-Opioid Receptor (MOPr) agonist (K_i=210 nM, hMOPr) .

HY-P3519

ACV Tripeptide	Peptides	Others
ACV Tripeptide is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide is synthesized by a large non-ribosomal peptide synthase called ACV synthase, which is encoded by the 11 kb The pchAB gene encodes this enzyme .

HY-P3044

Bilaid A1e	Opioid Receptor	Neurological Disease
Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the µ-opioid receptor (K_i = 750 nM). Bilaid A1e can be isolated from an Australian estuarine isolate of Penicillium sp. Bilaid A1e can be used for pain research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-120551

Fructigenine A	Structural Classification Natural Products Microorganisms Source classification	Others
Fructigenine A (compound 4) is a active product that can be isolated from marine-derived Penicillium sp. .

HY-N12184

Peniciside	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

HY-N12904

Communesin B (+)-Communesin B; Nomofungin	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium .

HY-N12911

Tanzawaic acid E	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Tanzawaic acid E is a carboxylic acid and can be isolated from Penicillium steckii .

HY-126697

Eremofortin A	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

HY-126484

Eremofortin B	Structural Classification Natural Products Microorganisms Source classification	Others
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

HY-116479

Citromycetin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Marine natural products Other Diseases Phenols Polyphenols Disease Research Fields Marine microorganism	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-N12266

12-Hydroxyalbrassitriol	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-129279

Andrastin A	Structural Classification Natural Products Microorganisms Source classification	Farnesyl Transferase
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species .

HY-N7480A

Quinolactacin A1	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Neurological Disease Source classification Quinoline Alkaloids Disease Research Fields	Cholinesterase (ChE)
Quinolactacin A1 is a potent acetylcholinesterase (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

HY-N12914

Tanzawaic acid B (+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Reactive Oxygen Species
Tanzawaic acid B ((+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E) is a superoxide anion production inhibitor and can be isolated from Penicillium citrinum .

HY-126604

Pyranonigrin A	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Others
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-N8287

Oxaline	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Microtubule/Tubulin
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N6748

Roquefortine C 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Cyclopeptides Source classification Disease Research Fields	P-glycoprotein Cytochrome P450 Bacterial Endogenous Metabolite
Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria .

HY-N12761

Penpaxilloids A	Structural Classification Terpenoids Marine natural products Source classification Diterpenoids Marine microorganism	Phosphatase Glucosidase
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Structural Classification Flavonoids Microorganisms Xanthones Source classification Phenols Other Flavonoids	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

HY-118463

Benzomalvin A	Alkaloids Human Gut Microbiota Metabolites Microorganisms Source classification Quinoline Alkaloids Endogenous metabolite	Neurokinin Receptor
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with K_i values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .

HY-N10177

Peniterphenyl A	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HSV
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-N10215

Canadensolide	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Fungal Endogenous Metabolite
Canadensolide is an antifungal metabolite of Penicillium canadense.

HY-N8548

Fellutanine A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-N7221

Janthitrem G	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Fungal
Janthitrem G is a microbial metabolite that can be isolated from cultures of Penicillium .

HY-125298

Cycloaspeptide A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .

HY-N11955

Cyclo(Ile-Leu)	Structural Classification Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification Endogenous metabolite	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-129208

Viridicatumtoxin	Other Terpenoids Infection Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields	Antibiotic Fungal
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

HY-123474

PF-1163B	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal Antibiotic
PF-1163B is an antifungal antibiotic .

HY-120154

Palitantin (±)-Palitantin	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite Endogenous Metabolite
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-N10220

Paraherquamide E	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite Parasite
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-125546

Erythromycin C	Structural Classification Natural Products Microorganisms Source classification	Antibiotic
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .

HY-N7222

Janthitrem F	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Fungal
Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease .

HY-N13086

Peniviridiol A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Others
Peniviridiol A (compound4) is a viridin derivative that can be isolated from rhizosphere fungus Penicillium sp. SMU0102 .

HY-125060

Viridicatin	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Quinoline Alkaloids Disease Research Fields	Antibiotic Endogenous Metabolite
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-N10442

Herqueilenone A	Quinones Structural Classification Microorganisms Source classification Benzene Quinones	Others
Herqueilenone A is a benzoquinone-chromanon that can be found in the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729[1].

HY-122404

Xantocillin Xanthocillin X	Structural Classification Microorganisms Classification of Application Fields Source classification Marine natural products Phenols Polyphenols Disease Research Fields Marine microorganism Cancer	MEK ERK Autophagy
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway .

HY-124301

Penicolinate A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Pyridine Alkaloids Disease Research Fields	Bacterial
Penicolinate A is a picolinic acid derivative. Penicolinate A is isolated from endophytic Penicillium sp. BCC16054. Penicolinate A exhibits antimalarial and antitubercular activities .

HY-126983

6',7'-Epoxybergamottin Epoxybergamottin	Structural Classification Natural Products Microorganisms Source classification	Others Endogenous Metabolite
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity .

HY-N8498

GKK1032B	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Apoptosis
GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation .

HY-N12169

Janthitrem A 11,12-Epoxyjanthitrem B	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Others
Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae .

HY-116474

Viridicatol	Infection Alkaloids Monophenols Microorganisms Classification of Application Fields Source classification Phenols Quinoline Alkaloids Disease Research Fields	Fungal
Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL .

HY-75564

Cyclo(Ala-Gly)	Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-N6688

Verruculogen	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Potassium Channel Bacterial Antibiotic
Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca ²⁺-activated K ⁺ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle .

HY-N6744

Chaetoglobosin A	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Marine natural products Endogenous metabolite Disease Research Fields Marine microorganism Indole Alkaloids	Apoptosis
Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration .

HY-N6779

Patulin 3 Publications Verification Terinin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Bacterial Apoptosis Autophagy Antibiotic
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

HY-116498

Penigequinolone A	Microorganisms Source classification	Others
Penigequinolone A is an alkaloid isolated from Penicillium. It is lethal to P. penetrans (LD50=100 mg/L) but has no effect on C. elegans at concentrations up to 1000 mg/L.1 Penigequinolone A also accelerates the root growth of rice seedlings in a dose-dependent manner.

HY-117517

NG-012	Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	Others
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-126775

Xenoclauxin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Xenoclauxin is a secondary metabolite isolated from certain species of the Penicillium genus, which exhibits an inhibitory effect on the proliferation of tumor cells. Xenoclauxin affects cellular energy metabolism, particularly by inhibiting ATP synthesis in the mitochondria. Xenoclauxin can be used for anti-tumor research .

HY-N6797

Meleagrin	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Bacterial c-Met/HGFR Antibiotic
Meleagrin is a roquefortine C-derived alkaloid produced by fungi of the genus Penicillium and has antimicrobial and anti-proliferative activities. Meleagrin is a class of FabI inhibitor. Meleagrin is a lead c-Met inhibitory entity useful for the control of c-Met-dependent metastatic and invasive breast malignancies .

HY-N6776

Penitrem A	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Potassium Channel
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals .

HY-N6745

Citreoviridin	Cardiovascular Disease Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Na+/K+ ATPase Apoptosis
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na ⁺/K ⁺-ATPase whereas in microsomes, both Na ⁺/K ⁺-ATPase and Mg ²⁺-ATPase activities are significantly stimulated in a dose-dependent manner . Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells .

HY-N8316

Rugulotrosin A	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Rugulotrosin A is an antibiotic originally isolated from Penicillium. It is active against the Gram-positive bacteria E. faecalis, B. cereus, B. subtilis, and S. aureus with 99% lethal dose (LD99) values of 1.6, 3.1, 5.5, and 200 μg/mL, respectively.1 Rugulotrosin A is inactive against Gram-negative bacteria.

HY-N6779R

Patulin (Standard)	Structural Classification Natural Products Microorganisms Source classification	Bacterial Apoptosis Autophagy Antibiotic
Patulin (Standard) is the analytical standard of Patulin. This product is intended for research and analytical applications. Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

Cat. No.	Product Name	Chemical Structure

HY-N6779S

Patulin-13C7
Patulin- ¹³C₇ (Terinin- ¹³C₇) is the ¹³C labeled Patulin (HY-N6779) . Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

HY-W015912S

2-Acetylfuran-d3

2-Acetylfuran-d₃ is deuterated labeled Citreoviridin (HY-N6745). Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na ⁺/K ⁺-ATPase whereas in microsomes, both Na ⁺/K ⁺-ATPase and Mg ²⁺-ATPase activities are significantly stimulated in a dose-dependent manner . Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells .

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