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Pathways Recommended:	Neuronal Signaling JAK/STAT Signaling

Results for "

Signal amplification

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (3) CDK (1) DNA Stain (3) Drug Derivative (1) Drug Intermediate (1) Fluorescent Dye (10) Isotope-Labeled Compounds (1) MMP (1) Radionuclide-Drug Conjugates (RDCs) (1) TAM Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (1) Metabolic Disease (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Isotope-Labeled Compounds

Targets Recommended: ERK ASK1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1840

Tyramide Amplification Buffer	Biochemical Assay Reagents	Others
Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .

HY-134418

NOTA	Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Cancer
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .

HY-125658

Biotinyl tyramide 5 Publications Verification	Fluorescent Dye	Others
Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-E70005I

Collagenase, Type VI Type VI collagenase	MMP	Cancer
Collagenase, Type VI (EC 3.4.24.3) is a collagenase that can degrade type VI collagen. Type VI collagen is a component of cell membranes in various tissues (such as skin, heart, blood vessels, cartilage, and synovial fluid). Excessive collagenase can cause extracellular matrix lesions. Collagenase is also a biomarker for tumor invasion and metastasis. Collagenase, Type VI can specifically act on the peptide bond between proline and glycine. This feature can be used to quickly and sensitively detect its concentration level in experiments using corresponding modified electrodes .

HY-160701

Cirtociclib BLU-222	CDK Apoptosis	Cancer
Cirtociclib (BLU-222) is an orally active and highly selective CDK2 inhibitor. Cirtociclib disrupts Rb signaling and causes G1 arrest and apoptosis in CCNE1-amplified endometrial cancer cells .

HY-111377

Amine-PEG3-Biotin 2 Publications Verification	Fluorescent Dye	Others
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .

HY-D2205

Cy7 tyramide Cy7 TSA	Fluorescent Dye	Others
Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	DNA Stain	Others
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-D1839

Biotin TSA（200×） Biotin Tyramide	Fluorescent Dye	Others
Biotin TSA (200×) (Biotin Tyramide) is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-125658S

Biotinyl tyramide-d4	Isotope-Labeled Compounds	Others
Biotinyl tyramide-d₄ is a deuterated labeled Biotinyl tyramide (HY-125658). Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-136248

Cyanine 3 Tyramide Tyramide-Cy3	DNA Stain Fluorescent Dye	Others
Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-131008

Fluorescein tyramide 1 Publications Verification	Fluorescent Dye	Others
Fluorescein tyramide is a green fluorescent reagent (λ_abs: 494 nm; λ_em: 517 nm). Fluorescein tyramide is widely used for tyramide signal amplification (TSA) with a low-abundance in IHC, ICC, in situ hybridization (FISH) and flow cytometry (FCM) applications .

HY-P2145

Extracellular death factor EDF	Bacterial	Infection
Extracellular death factor (EDF) is the only single signaling molecule involved in Escherichia coli quorum sensing, and can initiate MAZEF-mediated cell death. Extracellular death factor significantly amplifies the endoribonucleolytic activities of both MazF and ChpBK .

HY-136248A

Cyanine 3 Tyramide methyl indole	Fluorescent Dye	Others
Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-136247A

Cyanine 5 Tyramide methyl indole	DNA Stain	Others
Cyanine 5 Tyramide (Tyramide-Cy5) methyl indole is a red fluorescent dye. Cyanine 5 Tyramide is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids . Storage: protect from light.

HY-167931

Cinnamohydrazide	Drug Derivative	Metabolic Disease
Cinnamohydrazide, an unsaturated carboxylic acid derivative, serves as a precursor to aspartame through enzyme-mediated amination to phenylalanine. This compound may offer potential benefits in the prevention and treatment of diabetes by facilitating insulin secretion, enhancing pancreatic β-cell function, inhibiting hepatic gluconeogenesis, promoting glucose uptake, amplifying insulin signaling pathways, delaying carbohydrate digestion and glucose absorption, and reducing protein glycation and insulin fibrillation.

HY-12965B

(Z)-S49076 hydrochloride	TAM Receptor	Cancer
(Z)-S49076 hydrochloride is an orally active inhibitor of MET and AXL that blocks the downstream signaling of these receptors both in vitro and in vivo, inhibiting the proliferation and migration of tumor cells and suppressing tumor growth in xenograft models. (Z)-S49076 hydrochloride is capable of overcoming the resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) due to MET amplification in Erlotinib (HY-50896)-resistant cell lines both in vitro and in vivo. (Z)-S49076 hydrochloride can be used for research in non-small cell lung cancer (NSCLC) .

HY-173390

BCN-E-BCN	Drug Intermediate Biochemical Assay Reagents	Others
BCN-E-BCN is a strained cycloalkyne-based probe designed for detecting protein sulfenylation, the primary intermediate in protein oxidation. This structurally constrained cycloalkyne compound specifically recognizes sulfenic acid groups formed during thiol oxidation, while remaining completely unreactive toward other oxidative states (such as free thiols, sulfinic, or sulfonic acid groups). Researchers can leverage its efficient conjugation with azide-bearing tags through copper-free click chemistry to amplify detection signals. Compared to conventional detection methods, BCN-E-BCN demonstrates superior reaction kinetics and enhanced sensitivity. With these advantages, BCN-E-BCN shows great promise as an effective tool for protein oxidation research .

HY-D2738

BP Fluor 532 NHS ester	Fluorescent Dye	Others
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.

HY-W800701

BP Fluor 546 DBCO	Biochemical Assay Reagents	Others
BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes. BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.

HY-D2763

BP Fluor 532 maleimide	Fluorescent Dye	Others
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

HY-D2745

BP Fluor 594 NHS ester	Fluorescent Dye	Others
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection. BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.

Cat. No.	Product Name

HY-L015

PI3K/Akt/mTOR Compound Library	738 compounds
The PI3K/Akt/mTOR pathway controls many cellular processes that are important for the formation and progression of cancer, including apoptosis, transcription, translation, metabolism, angiogenesis, and cell cycle progression. Every major node of this signaling network is activated in a wide range of human tumors. Mechanisms for the pathway activation include activation of receptor tyrosine kinases (RTKs) upstream of PI3K, mutation or amplification of PIK3CA encoding p110α catalytic subunit of PI3K, mutation or loss of PTEN tumor suppressor gene, and mutation or amplification of Akt1. Once the pathway is activated, signaling through Akt can stimulate a series of substrates including mTOR which is involved in protein synthesis. Thus, inhibition of this pathway is an attractive concept for cancer prevention and/or therapy. Currently some mTOR inhibitors are approved for several indications, and there are several novel PI3K/Akt/mTOR inhibitors in clinical trials. MCE owns a unique collection of 738 compounds that can be used for PI3K/Akt/mTOR pathway research. PI3K/Akt/mTOR Compound Library also acts as a useful tool for anti-cancer drug discovery.

PI3K/Akt/mTOR Compound Library

738 compounds

The PI3K/Akt/mTOR pathway controls many cellular processes that are important for the formation and progression of cancer, including apoptosis, transcription, translation, metabolism, angiogenesis, and cell cycle progression. Every major node of this signaling network is activated in a wide range of human tumors. Mechanisms for the pathway activation include activation of receptor tyrosine kinases (RTKs) upstream of PI3K, mutation or amplification of PIK3CA encoding p110α catalytic subunit of PI3K, mutation or loss of PTEN tumor suppressor gene, and mutation or amplification of Akt1. Once the pathway is activated, signaling through Akt can stimulate a series of substrates including mTOR which is involved in protein synthesis. Thus, inhibition of this pathway is an attractive concept for cancer prevention and/or therapy. Currently some mTOR inhibitors are approved for several indications, and there are several novel PI3K/Akt/mTOR inhibitors in clinical trials.

MCE owns a unique collection of 738 compounds that can be used for PI3K/Akt/mTOR pathway research. PI3K/Akt/mTOR Compound Library also acts as a useful tool for anti-cancer drug discovery.

HY-L147

Protease Inhibitor Library	724 compounds
A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals. Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 724 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

Protease Inhibitor Library

724 compounds

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 724 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

Cat. No.	Product Name	Type

HY-D1840

Tyramide Amplification Buffer	Dyes
Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .

Tyramide Amplification Buffer

Dyes

Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .

HY-111377

Amine-PEG3-Biotin 2 Publications Verification	Chromogenic Assays
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .

HY-D2205

Cy7 tyramide Cy7 TSA	Fluorescent Dyes/Probes
Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	Fluorescent Dyes/Probes
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-136248

Cyanine 3 Tyramide Tyramide-Cy3	Fluorescent Dyes/Probes
Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-136248A

Cyanine 3 Tyramide methyl indole	Fluorescent Dyes/Probes
Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-D1839

Biotin TSA（200×） Biotin Tyramide	Dyes
Biotin TSA (200×) (Biotin Tyramide) is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-D2738

BP Fluor 532 NHS ester	Fluorescent Dyes/Probes
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.

BP Fluor 532 NHS ester

Fluorescent Dyes/Probes

BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.

HY-W800701

BP Fluor 546 DBCO	Fluorescent Dyes/Probes
BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes. BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.

BP Fluor 546 DBCO

Fluorescent Dyes/Probes

BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes. BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.

HY-D2763

BP Fluor 532 maleimide	Fluorescent Dyes/Probes
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

BP Fluor 532 maleimide

Fluorescent Dyes/Probes

BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

HY-D2745

BP Fluor 594 NHS ester	Fluorescent Dyes/Probes
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection. BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.

BP Fluor 594 NHS ester

Fluorescent Dyes/Probes

BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection. BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.

Cat. No.	Product Name	Target	Research Area

HY-P2145

Extracellular death factor EDF	Bacterial	Infection
Extracellular death factor (EDF) is the only single signaling molecule involved in Escherichia coli quorum sensing, and can initiate MAZEF-mediated cell death. Extracellular death factor significantly amplifies the endoribonucleolytic activities of both MazF and ChpBK .

Cat. No.	Product Name	Chemical Structure

HY-125658S

Biotinyl tyramide-d4
Biotinyl tyramide-d₄ is a deuterated labeled Biotinyl tyramide (HY-125658). Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

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