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Results for "

active intermediate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (8) Antibiotic (4) Apoptosis (6) Bacterial (5) Bcr-Abl (1) Biochemical Assay Reagents (5) Calcium Channel (1) Cytochrome P450 (2) Drug Derivative (1) Drug Metabolite (3) Endogenous Metabolite (15) Fungal (1) GABA Receptor (1) Glucosylceramide Synthase (GCS) (1) Glutathione S-transferase (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (2) Keap1-Nrf2 (1) Ligands for E3 Ligase (1) Liposome (1) NO Synthase (1) Proteasome (1) RAR/RXR (1) Reactive Oxygen Species (1) Trk Receptor (2)
By Research Areas:	Cancer (13) Cardiovascular Disease (3) Infection (6) Inflammation/Immunology (9) Metabolic Disease (1) Neurological Disease (8)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: Drug Intermediate

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1230

4-Pentynoic acid Propargylacetic acid	Biochemical Assay Reagents	Others
4-Pentynoic acid (Propargylacetic acid) is an *intermediate* to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers . 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-Y0038

2-Bromo-6-methoxynaphthalene	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-Y0038R

2-Bromo-6-methoxynaphthalene (Standard)	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene (Standard) is the analytical standard of 2-Bromo-6-methoxynaphthalene. This product is intended for research and analytical applications. 2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-B0989

Carzenide 4-Sulfamoylbenzoic acid	Drug Intermediate	Others
Carzenide is an organic synthesis intermediate used for the synthesis of active molecules.

HY-W012860

p-Tolualdehyde 2 Publications Verification	Drug Intermediate	Others
p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-113864

Diisobutyl carbinol	Drug Metabolite	Metabolic Disease
Diisobutyl carbinol (DIBC) is an orally active organic solvent widely used as industrial intermediates and fragrance ingredient. Diisobutyl carbinol and Diisobutyl ketone are well interconverted metabolically in rats .

HY-41940

Dasatinib intermediate-1	Bcr-Abl	Cancer
Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity .

HY-W016779

Cyclopentyl phenyl ketone	Endogenous Metabolite	Others
Cyclopentyl phenyl ketone is an organic synthesis intermediate used for the synthesis of active molecules .

HY-W708309

2-Methoxy ketamine hydrochloride	Drug Derivative	Others
2-Methoxy ketamine hydrochloride is an organic synthesis intermediate used for the synthesis of active molecules.

HY-W156596

3-Methoxybenzothioamide	Drug Intermediate	Others
3-Methoxybenzothioamide is an active small molecule, that can be ussed as drug intermediate .

HY-W010611

3-Methylbut-2-enoic acid	Bacterial	Infection
3-Methylbut-2-enoic acid is an active small molecule, that can be used as drug intermediate .

HY-W877989

BWA-522 intermediate-1	Ligands for E3 Ligase	Cancer
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7 .

HY-W078632

2-Mercapto-4,6-dimethylnicotinonitrile	Drug Intermediate	Others
2-Mercapto-4,6-dimethylnicotinonitrile can be used as an intermediate to synthesize biologically active compounds, such as aminomethyl derivatives .

HY-126181

5-Formylcytosine	Endogenous Metabolite	Others
5-Formylcytosine is a modified base, which is oxidized from 5-methylcytosine. 5-Formylcytosine is a intermediate of in the active DNA demethylation .

HY-115243

2-Chloro-1,4-naphthoquinone	Drug Intermediate	Others
2-Chloro-1,4-naphthoquinone is an reactive intermediate. 2-Chloro-1,4-naphthoquinone can be used for the research of various biochemical studies .

HY-133952

7-Oxotridecanedioic acid	Liposome	Cancer
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents	Others
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-135380

Atorvastatin acetonide tert-butyl ester	Drug Intermediate	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-76082

L-Pyroglutamic acid 2 Publications Verification	Endogenous Metabolite	Inflammation/Immunology
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-76082S

L-Pyroglutamic acid-d5 1 Publications Verification	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-108932

Gemcitabine monophosphate Gemcitabine 5′-phosphate	Apoptosis	Cancer
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .

HY-108932A

Gemcitabine monophosphate disodium Gemcitabine 5′-phosphate disodium	Apoptosis	Cancer
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .

HY-14843

Imagabalin PD-0332334(free base)	GABA Receptor	Neurological Disease
Imagabalin (PD-0332334 free base) is an active compound with activity for studying neurological diseases. The synthesis of imagabalin involves the reaction of 3-methylvaleric acid and Meldrum acid. During the synthesis of imagabalin, an acyl chloride intermediate species, 3-methylvaleryl chloride, was revealed for the first time. The synthesis of imagabalin also provided new information about the reaction mechanism, indicating that 3-methylvaleric anhydride is an important intermediate .

HY-B2124

10,11-Dihydrocarbamazepine	Drug Metabolite	Neurological Disease
10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy .

HY-B0242

Sulfanilamide 1 Publications Verification Sulphanilamide	Bacterial Antibiotic	Infection
ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-76082S1

L-Pyroglutamic acid-13C5	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Pyroglutamic acid-13C5 is a deuterated labeled L-Pyroglutamic acid . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-N0420A

Succinic acid tromethamine Wormwood acid tromethamine	Endogenous Metabolite	Neurological Disease
Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-125598

Secologanin	Cytochrome P450	Others
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin .

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	Endogenous Metabolite	Others
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-N14756

6-Deamino-6-hydroxyneomycin	Antibiotic Bacterial	Infection
6-Deamino-6-hydroxyneomycin is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6-Deamino-6-hydroxyneomycin can be used as an intermediate in the biosynthesis of neomycin and paromycin .

HY-N0420S4

Succinic acid-13C2	Endogenous Metabolite	Neurological Disease
Succinic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-N0420S3

Butanedioic acid-13C2	Endogenous Metabolite	Neurological Disease
Butanedioic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-N0420S2

Succinic acid-13C4	Endogenous Metabolite	Neurological Disease
Succinic acid- ¹³C₄ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-B0242R

Sulfanilamide (Standard)	Bacterial Antibiotic	Infection
Sulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-76082R

L-Pyroglutamic acid (Standard)	Endogenous Metabolite	Inflammation/Immunology
L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid. This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid standard can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-N3007

Naringenin chalcone 2 Publications Verification	Drug Intermediate Apoptosis NO Synthase	Inflammation/Immunology Cancer
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties .

HY-135380R

Atorvastatin acetonide tert-butyl ester (Standard)	Drug Intermediate	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-P5422

Caloxin 3A1	Calcium Channel	Others
Caloxin 3A1 is a biological active peptide. (This peptide belongs to caloxins, the extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 3A1 inhibits plasma membrane calcium pumps (PMCAs) but not the sarcoplasmic reticulum Ca2+-pump. This peptide does not inhibit formation of the acylphosphate intermediate from ATP.)

HY-N14758

6-Deamino-6-hydroxyparomomycin	Antibiotic Bacterial	Infection
6-Deamino-6-hydroxyparomomycin is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both gram-positive and Gram-negative bacteria. 6-Deamino-6-hydroxyparomomycin can be used as an intermediate in the biosynthesis of neomycin and paromomycin .

HY-N1282

Seneciphylline	Glutathione S-transferase Cytochrome P450	Cancer
Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research[1][2].

HY-W698250

3-Ferrocenylpropionic anhydride	Biochemical Assay Reagents Endogenous Metabolite
3-Ferrocenylpropionic anhydride is an important organic compound with good biological activity. 3-Ferrocenylpropionic anhydride is widely used in compound synthesis and can be used as a synthetic intermediate to participate in the production of a variety of biologically active compounds. 3-Ferrocenylpropionic anhydride exhibits potential anti-tumor properties by regulating specific enzyme activities.

HY-113335

Trihydroxycholestanoic acid Coprocholic acid	Endogenous Metabolite	Inflammation/Immunology
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease .

HY-N2292

Kinsenoside 1 Publications Verification	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).

HY-B2124R

10,11-Dihydrocarbamazepine (Standard)	Drug Metabolite	Neurological Disease
10,11-Dihydrocarbamazepine (Standard) is the analytical standard of 10,11-Dihydrocarbamazepine. This product is intended for research and analytical applications. 10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy .

HY-W127651

Dimethyldioctylammonium bromide Dioctyldimethylammonium bromide	Biochemical Assay Reagents	Others
Dimethyldioctylammonium bromide is an organic compound containing ammonium and bromide ions. It is commonly used in the production of detergents, emulsifiers and surfactants for various industrial applications. Dimethyldioctylammonium bromide is highly surface active and reduces the surface tension of aqueous solutions, so it can be used to clean and wet surfaces. In addition, it can also be used as an intermediate in the synthesis of other quaternary ammonium compounds.

HY-170541

FUT8-IN-1	Glucosylceramide Synthase (GCS)	Inflammation/Immunology
FUT8-IN-1 (Compound 37) is an inhibitor for α-1,6-fucosyltransferase (FUT8) with an K_D of 49 nM and an IC₅₀ of ca. 50 µM. FUT8-IN-1 generates a highly active naphthoquinone imine intermediate in the presence of FUT8, and inhibits the enzymatic activity of FUT8 .

HY-N3007R

Naringenin chalcone (Standard)	Others	Inflammation/Immunology
Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.

HY-159732

PRMT3-IN-4	Histone Methyltransferase	Cancer
PRMT3-IN-4 (intermediate 15) is a protein arginine methyltransferase 3 (PRMT3) inhibitor. PRMT3-IN-4 is an active control for HY-19715. PRMT3-IN-4 can be used to synthesize PROTACs targeting PRMT3. PRMT3-IN-4 can be used in leukemia-related research .

HY-78509

Dibenzosuberone	Biochemical Assay Reagents	Neurological Disease
Dibenzosuberone belongs to the family of tricyclic antidepressant drugs, commonly referred to as Tricyclic antidepressants (TCAs), and is widely used in research on migraine, tension headaches, anxiety disorders, and schizophrenia. Dibenzosuberone is also a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs), such as Amitriptyline (HY-B0527), Nortriptyline (HY-118620), Noxiptiline or Cyproheptadine (HY-B1622) .

HY-151424

Vimentin-IN-1	Proteasome	Cancer
Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin (VIM), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1 .

Cat. No.	Product Name	Type

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-133952

7-Oxotridecanedioic acid	Drug Delivery
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

HY-W127651

Dimethyldioctylammonium bromide

Dioctyldimethylammonium bromide

Cell Assay Reagents

Dimethyldioctylammonium bromide is an organic compound containing ammonium and bromide ions. It is commonly used in the production of detergents, emulsifiers and surfactants for various industrial applications. Dimethyldioctylammonium bromide is highly surface active and reduces the surface tension of aqueous solutions, so it can be used to clean and wet surfaces. In addition, it can also be used as an intermediate in the synthesis of other quaternary ammonium compounds.

Cat. No.	Product Name	Target	Research Area

HY-P5422

Caloxin 3A1	Calcium Channel	Others
Caloxin 3A1 is a biological active peptide. (This peptide belongs to caloxins, the extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 3A1 inhibits plasma membrane calcium pumps (PMCAs) but not the sarcoplasmic reticulum Ca2+-pump. This peptide does not inhibit formation of the acylphosphate intermediate from ATP.)

HY-P5510

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 HCV NS3 protease substrate	Peptides	Others
Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012860

p-Tolualdehyde 2 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Intermediate
p-Tolualdehyde is the active small molecule, that could used as drug intermediate .

HY-W010611

3-Methylbut-2-enoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Bacterial
3-Methylbut-2-enoic acid is an active small molecule, that can be used as drug intermediate .

HY-76082

L-Pyroglutamic acid 2 Publications Verification	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-125598

Secologanin	Structural Classification Caprifoliaceae Iridoids Classification of Application Fields Lonicera japonica Thunb. Terpenoids Source classification Other Diseases Plants Disease Research Fields	Cytochrome P450
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin .

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-76082R

L-Pyroglutamic acid (Standard)	Structural Classification Immune System Disorder Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid. This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid standard can be used as a biomarker for systemic lupus erythematosus (SLE) .

HY-N3007

Naringenin chalcone 2 Publications Verification	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Chalcones Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Drug Intermediate Apoptosis NO Synthase
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties .

HY-N0420A

Succinic acid tromethamine Wormwood acid tromethamine	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .

HY-N14756

6-Deamino-6-hydroxyneomycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
6-Deamino-6-hydroxyneomycin is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6-Deamino-6-hydroxyneomycin can be used as an intermediate in the biosynthesis of neomycin and paromycin .

HY-N14758

6-Deamino-6-hydroxyparomomycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
6-Deamino-6-hydroxyparomomycin is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both gram-positive and Gram-negative bacteria. 6-Deamino-6-hydroxyparomomycin can be used as an intermediate in the biosynthesis of neomycin and paromomycin .

HY-N1282

Seneciphylline	Alkaloids Structural Classification other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Compositae Sophora yunnanensis C. Y. Ma Disease Research Fields Cancer	Glutathione S-transferase Cytochrome P450
Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research[1][2].

HY-113335

Trihydroxycholestanoic acid Coprocholic acid	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease .

HY-N2292

Kinsenoside 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Orchidaceae Plants Anoectochilus Inflammation/Immunology Disease Research Fields	Keap1-Nrf2 Apoptosis
Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).

HY-N3007R

Naringenin chalcone (Standard)	Structural Classification Human Gut Microbiota Metabolites Chalcones Flavonoids other families Source classification Phenols Polyphenols Plants Endogenous metabolite	Others
Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.

HY-W012814

4-Methylcatechol	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis Reactive Oxygen Species
4-Methylcatechol is an intermediate in the degradation of some alkylbenzenes and an orally active suicide inhibitor of catechol 2,3-dioxygenase (C23O). 4-Methylcatechol induces apoptosis in melanoma cells through oxidative stress, but some studies have also shown that 4-Methylcatechol is carcinogenic. In addition, 4-Methylcatechol has antiplatelet and blood pressure-lowering activities. 4-Methylcatechol can also inhibit protein oxidation in beef but does not disulfide formation .

HY-W014589

2,4-Di-tert-butylphenol 1 Publications Verification 2,4-DTBP	Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Fungal Apoptosis RAR/RXR
2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of medicines and fragrances .

Cat. No.	Product Name	Chemical Structure

HY-76082S

L-Pyroglutamic acid-d5 1 Publications Verification
L-Pyroglutamic acid-d₅ is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-N0420S3

Butanedioic acid-13C2
Butanedioic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-N0420S2

Succinic acid-13C4
Succinic acid- ¹³C₄ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

HY-76082S1

L-Pyroglutamic acid-13C5
L-Pyroglutamic acid-13C5 is a deuterated labeled L-Pyroglutamic acid . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

HY-N0420S4

Succinic acid-13C2
Succinic acid- ¹³C₂ is the ¹³C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

Cat. No.	Product Name		Classification

HY-Y1230

4-Pentynoic acid Propargylacetic acid		Alkynes
4-Pentynoic acid (Propargylacetic acid) is an *intermediate* to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers . 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-133952

7-Oxotridecanedioic acid		Cationic Lipids
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

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