Search Result
Results for "
anti-protozoal
" in MedChemExpress (MCE) Product Catalog:
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B1147
-
|
Parasite
|
Infection
|
Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
|
-
-
- HY-119972
-
|
Parasite
|
Infection
|
Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its proagent Diloxanide furoate (HY-B1147) .
|
-
-
- HY-N0914
-
Ajugol
2 Publications Verification
|
Parasite
|
Others
|
Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC50 of 31.8 μg/mL .
|
-
-
- HY-16349
-
K-1900
|
Parasite
Antibiotic
|
Infection
Cancer
|
Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
|
-
-
- HY-101660
-
-
-
- HY-P5696
-
|
Bacterial
Parasite
Fungal
|
Infection
|
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .
|
-
-
- HY-N10547
-
|
Parasite
|
Infection
|
6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC50: 32.5 and 8.3 μg/mL) .
|
-
-
- HY-B1147R
-
|
Parasite
|
Infection
|
Diloxanide furoate (Standard) is the analytical standard of Diloxanide furoate. This product is intended for research and analytical applications. Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
|
-
-
- HY-N0914R
-
|
Parasite
|
Others
|
Ajugol (Standard) is the analytical standard of Ajugol. This product is intended for research and analytical applications. Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC50 of 31.8 μg/mL .
|
-
-
- HY-16349R
-
|
Parasite
Antibiotic
|
Infection
Cancer
|
Nimorazole (Standard) is the analytical standard of Nimorazole. This product is intended for research and analytical applications. Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
|
-
-
- HY-P3451
-
-
-
- HY-17581
-
-
-
- HY-N6587
-
Methyl betulinate
|
Parasite
|
Others
|
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .
|
-
-
- HY-B0175
-
-
-
- HY-B0217S
-
NTZ-d4; NSC-697855-d4
|
Influenza Virus
|
Others
|
Nitazoxanide-d4 is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.
|
-
-
- HY-147766
-
|
Parasite
|
Infection
|
Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent .
|
-
-
- HY-119900
-
|
Parasite
Antibiotic
|
Infection
|
Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
|
-
-
- HY-B2138
-
Ethyl pabate
|
Parasite
Antibiotic
|
Infection
|
Ethopabate is an antiprotozoal agent which has been widely used to treat and prevent coccidiosis in chickens.
|
-
-
- HY-147765
-
|
Parasite
|
Infection
|
Anti-Trypanosoma cruzi agent-3 (Compound 7c) is an antiprotozoal agent .
|
-
-
- HY-N11100
-
|
Parasite
|
Infection
|
Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum .
|
-
-
- HY-B0508
-
-
-
- HY-135611A
-
|
Parasite
Antibiotic
|
Infection
|
Imidocarb dihydrochloride monohydrate is a potent antiprotozoal agent. Imidocarb dihydrochloride monohydrate is active against the parasite B. bovis with an IC50 of 87 μg/mL .
|
-
-
- HY-120154
-
(±)-Palitantin
|
Parasite
Endogenous Metabolite
|
Infection
|
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .
|
-
-
- HY-135611
-
|
Parasite
Antibiotic
|
Infection
|
Imidocarb is a potent antiprotozoal agent. Imidocarb is active against the parasite B. bovis with an IC50 of 87 μg/mL .
|
-
-
- HY-118996A
-
|
Parasite
|
Infection
|
Isometamidium chloride is an antiprotozoal agent, that exhibits activity against trypanosome. Isometamidium chloride can be used in research of african sleeping sickness .
|
-
-
- HY-107496
-
|
Parasite
Antibiotic
|
Infection
|
Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL .
|
-
-
- HY-B1143
-
Brobenzoxaldine
|
Parasite
Fungal
Bacterial
|
Infection
|
Broxaldine (Brobenzoxaldine) is an antiprotozoal agent. Broxaldine inhibits Clostridium difficile with a MIC value of 4 µM, and has antifungal effects .
|
-
-
- HY-B0175S
-
BAY-i 9142-d3
|
Isotope-Labeled Compounds
|
Infection
|
Toltrazuril-d3 is deuterated labeled Toltrazuril. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
|
-
-
- HY-17581R
-
|
Parasite
Antibiotic
|
Infection
|
Buparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
|
-
-
- HY-B1336
-
-
-
- HY-18257
-
|
Bacterial
Antibiotic
|
Infection
|
Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic . Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent .
|
-
-
- HY-N10255
-
|
Parasite
|
Infection
|
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process .
|
-
-
- HY-119900S
-
|
Isotope-Labeled Compounds
|
Infection
|
Carnidazole-d3 is deuterium labeled Carnidazole (HY-119900). Carnidazole exhibits antiprotozoal efficacy against Trichomonas gallinae .
|
-
-
- HY-B0175R
-
|
Parasite
Antibiotic
|
Infection
|
Toltrazuril (Standard) is the analytical standard of Toltrazuril. This product is intended for research and analytical applications. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
|
-
-
- HY-17008
-
Ponazuril
|
Parasite
|
Infection
|
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .
|
-
-
- HY-18715
-
(S)-Ornidazole; Levornidazole
|
Bacterial
Parasite
|
Infection
|
Ornidazole Levo- is the levo-isomer of Ornidazole. Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Ornidazole Levo- is the less active isomer.
|
-
-
- HY-115249
-
|
Bacterial
Parasite
Antibiotic
|
Infection
|
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
-
- HY-119900R
-
|
Parasite
Antibiotic
|
Infection
|
Carnidazole (Standard) is the analytical standard of Carnidazole. This product is intended for research and analytical applications. Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
|
-
-
- HY-W040073
-
|
Parasite
Lactate Dehydrogenase
|
Infection
Cancer
|
Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).
|
-
-
- HY-W079315
-
|
Parasite
|
Infection
|
5-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities .
|
-
-
- HY-101590A
-
L 16726 dihydrochloride
|
Parasite
|
Infection
|
Symetine dihydrochloride (L 16726 dihydrochloride) is the dihydrochloride form of Symetine (HY-101590). Symetine dihydrochloride exhibits antiprotozoal activity aginst Entamoeba histolytica, and ameliorates the amebic liver abscess in guinea pig model .
|
-
-
- HY-B2138R
-
|
Parasite
Antibiotic
|
Infection
|
Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate is an antiprotozoal agent which has been widely used to treat and prevent coccidiosis in chickens.
|
-
-
- HY-101848
-
|
Fungal
|
Infection
|
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .
|
-
-
- HY-N11173
-
|
Others
|
Metabolic Disease
|
cis-Melilotoside, an o-Coumaric acid derivative, shows potent antioxidant activity. cis-Melilotoside has antiprotozoal activity moderately against T. cruzi with an IC50 of 78.2 ug/mL .
|
-
-
- HY-G0016
-
MADDS; Monoacetyldapsone
|
Drug Metabolite
|
Others
|
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .
|
-
-
- HY-169289
-
|
Parasite
|
Infection
|
PIQ-2 (compound 54) is a antiprotozoal agent with the IC50 values of 9.4 nM and 1.6 nM against IP. falciparum 3D7I and B. divergens Rouen,respectively .
|
-
-
- HY-B0565
-
|
Parasite
Bacterial
|
Infection
|
Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery .
|
-
-
- HY-100711
-
Prodigiosine; NSC47147
|
Bacterial
Apoptosis
Wnt
Fungal
Parasite
|
Infection
Inflammation/Immunology
Cancer
|
Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
|
-
-
- HY-B0508S1
-
-
-
- HY-N7632
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC50 values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .
|
-
- HY-114275
-
|
Fungal
Parasite
Apoptosis
|
Infection
Cardiovascular Disease
Cancer
|
Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation .
|
-
- HY-B1336R
-
|
Bacterial
Apoptosis
Antibiotic
Parasite
|
Infection
Cancer
|
Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM.
|
-
- HY-107496R
-
|
Parasite
Antibiotic
|
Infection
|
Imidocarb (dipropionate) (Standard) is the analytical standard of Imidocarb (dipropionate). This product is intended for research and analytical applications. Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL .
|
-
- HY-136438
-
-
- HY-100711A
-
Prodigiosine hydrochloride
|
Bacterial
Apoptosis
Fungal
Wnt
Parasite
|
Infection
Inflammation/Immunology
Cancer
|
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
|
-
- HY-W040073S
-
|
Isotope-Labeled Compounds
Parasite
Lactate Dehydrogenase
|
Infection
Cancer
|
Nifurtimox-d4 is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).
|
-
- HY-B0295
-
|
Bacterial
Antibiotic
Parasite
|
Infection
|
Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
|
-
- HY-19910
-
SCYX-7158; AN5568
|
Parasite
|
Infection
|
Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 µg/mL .
|
-
- HY-N9179
-
|
Parasite
|
Infection
|
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL) .
|
-
- HY-119604
-
|
Antibiotic
Bacterial
|
Infection
|
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .
|
-
- HY-19594
-
WIN 13146
|
Parasite
|
Infection
|
Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections .
|
-
- HY-W040073R
-
|
Parasite
Lactate Dehydrogenase
|
Infection
Cancer
|
Nifurtimox (Standard) is the analytical standard of Nifurtimox. This product is intended for research and analytical applications. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).
|
-
- HY-17008R
-
|
Parasite
|
Infection
|
Toltrazuril (sulfone) (Standard) is the analytical standard of Toltrazuril (sulfone). This product is intended for research and analytical applications. Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .
|
-
- HY-115249R
-
|
Parasite
Antibiotic
Bacterial
|
Infection
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-147857
-
|
Parasite
|
Infection
|
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively .
|
-
- HY-147856
-
|
Parasite
|
Infection
|
Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 28.3, 24.8 and 13.0 μM, respectively .
|
-
- HY-B0565S
-
|
Isotope-Labeled Compounds
|
Others
|
Ronidazole-d3is the deuterium labeledRonidazole(HY-B0565) . Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery .
|
-
- HY-N7516
-
|
Parasite
Bacterial
Fungal
|
Infection
|
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .
|
-
- HY-P2450
-
antibiotic P168
|
Fungal
Antibiotic
|
Infection
Cancer
|
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .
|
-
- HY-B0565R
-
|
Parasite
Bacterial
|
Infection
|
Ronidazole (Standard) is the analytical standard of Ronidazole. This product is intended for research and analytical applications. Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery .
|
-
- HY-P1954
-
Piscidin-1 (22-42)
|
Bacterial
|
Infection
Cancer
|
Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .
|
-
- HY-P1954A
-
Piscidin-1 (22-42) (TFA)
|
Bacterial
|
Infection
|
Epinecidin-1 (Piscidin-1 (22-42)) TFA is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .
|
-
- HY-155281
-
|
Parasite
|
Infection
|
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC50=0.4 μM), T. cruzi (EC50=0.21 μM), and L. donovani (EC50=0.26 μM). Antiparasitic agent-18 has potent antiprotozoal activity .
|
-
- HY-136438R
-
|
Endogenous Metabolite
Parasite
|
Metabolic Disease
Inflammation/Immunology
|
Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites .
|
-
- HY-B0295R
-
|
Bacterial
Antibiotic
Parasite
|
Infection
|
Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
|
-
- HY-19594R
-
|
Parasite
|
Infection
|
Teclozan (Standard) is the analytical standard of Teclozan. This product is intended for research and analytical applications. Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections .
|
-
- HY-B0226A
-
(E)-Nitrofural
|
Bacterial
Parasite
|
Infection
|
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .
|
-
- HY-B0688
-
Dapsone
1 Publications Verification
4,4′-Diaminodiphenyl sulfone; DDS
|
Antibiotic
Parasite
Bacterial
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
|
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
|
-
- HY-146487
-
|
Bacterial
Parasite
|
Infection
|
Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .
|
-
- HY-B0740
-
MK130 hydrochloride
|
5-HT Receptor
Parasite
|
Infection
Neurological Disease
|
Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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- HY-B0688S1
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4,4′-Diaminodiphenyl sulfone-d4; DDS-d4
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Antibiotic
Parasite
Bacterial
Reactive Oxygen Species
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Infection
Inflammation/Immunology
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Dapsone-d4 is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].
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- HY-B0740R
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MK130 hydrochloride (Standard)
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5-HT Receptor
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Neurological Disease
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Cyclobenzaprine (MK130) hydrochloride (Standard) is the analytical standard of Cyclobenzaprine (MK130) hydrochloride. This product is intended for research and analytical applications. Cyclobenzaprine hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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- HY-B0688R
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Antibiotic
Parasite
Bacterial
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
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Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
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- HY-A0059
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NF 113; SAP 113; Methylmercadone
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Bacterial
Parasite
Antibiotic
Fungal
Apoptosis
STAT
Interleukin Related
TNF Receptor
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Infection
Inflammation/Immunology
Cancer
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Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .
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- HY-B0688S2
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4,4′-Diaminodiphenyl sulfone-13C12; DDS-13C12
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Isotope-Labeled Compounds
Antibiotic
Parasite
Bacterial
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
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Dapsone- 13C12 is the 13C12 labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
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- HY-B0740S3
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MK130-d3-1 hydrochloride
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Isotope-Labeled Compounds
5-HT Receptor
Parasite
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Infection
Neurological Disease
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Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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- HY-130743
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Bis-eugenol; Dehydrodieugenol
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Parasite
|
Infection
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Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P1954A
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Piscidin-1 (22-42) (TFA)
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Bacterial
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Infection
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Epinecidin-1 (Piscidin-1 (22-42)) TFA is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .
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- HY-P5696
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|
Bacterial
Parasite
Fungal
|
Infection
|
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .
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- HY-P3451
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- HY-P1954
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Piscidin-1 (22-42)
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Bacterial
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Infection
Cancer
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Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N0914
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-
-
- HY-B0508
-
-
-
- HY-101848
-
-
-
- HY-N10547
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-
-
- HY-N0914R
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-
-
- HY-N6587
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-
-
- HY-N11100
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-
-
- HY-120154
-
-
-
- HY-N10255
-
-
-
- HY-N11173
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-
-
- HY-100711
-
-
-
- HY-N7632
-
-
-
- HY-114275
-
-
-
- HY-136438
-
-
-
- HY-100711A
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-
-
- HY-N9179
-
|
Infection
Flavonoids
Classification of Application Fields
Flavones
Source classification
Lupinus perennis L.
Plants
Compositae
Disease Research Fields
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Parasite
|
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL) .
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-
-
- HY-119604
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-
-
- HY-N7516
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-
-
- HY-P2450
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-
-
- HY-136438R
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-
Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0217S
-
|
Nitazoxanide-d4 is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.
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-
-
- HY-B0175S
-
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Toltrazuril-d3 is deuterated labeled Toltrazuril. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
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-
-
- HY-119900S
-
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Carnidazole-d3 is deuterium labeled Carnidazole (HY-119900). Carnidazole exhibits antiprotozoal efficacy against Trichomonas gallinae .
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-
-
- HY-B0508S1
-
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Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
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-
-
- HY-W040073S
-
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Nifurtimox-d4 is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).
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-
-
- HY-B0565S
-
|
Ronidazole-d3is the deuterium labeledRonidazole(HY-B0565) . Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery .
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-
-
- HY-B0688S1
-
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Dapsone-d4 is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].
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-
-
- HY-B0688S2
-
|
Dapsone- 13C12 is the 13C12 labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
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-
-
- HY-B0740S3
-
|
Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
|
-
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