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bacterial ribosome

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15662
    Tulathromycin A
    1 Publications Verification

    Tulathromycin; CP 472295

    		 Antibiotic Bacterial Infection
    Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .
    Tulathromycin A
  • HY-141667
    MBD

    7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole

    		 Fluorescent Dye Others
    MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule .
    MBD
  • HY-B1329
    Apramycin sulfate
    3 Publications Verification

    Nebramycin II sulfate

    		 Bacterial Antibiotic Infection
    Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
    Apramycin sulfate
  • HY-B0438
    Spectinomycin dihydrochloride
    3 Publications Verification

    		 Bacterial Antibiotic Infection
    Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
    Spectinomycin dihydrochloride
  • HY-B1828A
    Spectinomycin dihydrochloride pentahydrate
    3 Publications Verification

    Spectinomycin hydrochloride hydrate

    		 Bacterial Antibiotic Infection
    Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
    Spectinomycin dihydrochloride pentahydrate
  • HY-139554
    Zifanocycline

    KBP-7072

    		 Bacterial Infection
    Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
    Zifanocycline
  • HY-15662R
    Tulathromycin A (Standard)

    		Antibiotic Bacterial Infection
    Tulathromycin A (Standard) is the analytical standard of Tulathromycin A. This product is intended for research and analytical applications. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .
    Tulathromycin A (Standard)
  • HY-B1329R
    Apramycin (sulfate) (Standard)

    		Bacterial Antibiotic Infection
    Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
    Apramycin (sulfate) (Standard)
  • HY-B1828
    Spectinomycin

    		Antibiotic Bacterial Infection
    Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .
    Spectinomycin
  • HY-W928617
    Spectinomycin sulfate hydrate

    		Antibiotic Bacterial Infection
    Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
    Spectinomycin sulfate hydrate
  • HY-153222
    SEQ-9

    		Bacterial Infection
    SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance .
    SEQ-9
  • HY-B1366A
    Meclocycline

    		Bacterial Antibiotic Infection
    Meclocycline is a tetracycline derivative. The main target of tetracyclines is the bacterial ribosome .
    Meclocycline
  • HY-161980
    Topoisomerases/ribosomes-IN-1

    		Topoisomerase Infection
    Topoisomerases/ribosomes-IN-1 (compound 30f) is an inhibitor of ribosomes and topoisomerases, and has inhibitory effects on constitutively macrolide-resistant bacteria. Topoisomerases/ribosomes-IN-1 can inhibit bacterial protein synthesis (IC50: 0.647 μM) and DNA replication (IC50: 0.218 μM) .
    Topoisomerases/ribosomes-IN-1
  • HY-112565
    MBX-4132
    1 Publications Verification

    		 Bacterial Infection
    MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
    MBX-4132
  • HY-16908A
    Lefamulin acetate
    1 Publications Verification

    BC-3781 acetate

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin acetate
  • HY-16908
    Lefamulin

    BC-3781

    		 Bacterial Antibiotic Infection
    Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin has anti-inflammatory activity. Lefamulin can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin
  • HY-116010A
    Oleandomycin phosphate

    		Antibiotic Bacterial Infection
    Oleandomycin phosphate is the phosphate salt form of Oleandomycin (HY-116010). Oleandomycin phosphate is an antibiotic, which exhibits antibacterial activity by binding to bacterial ribosomes and inhibiting protein synthesis .
    Oleandomycin phosphate
  • HY-111903
    Levomecol

    		Bacterial Infection
    Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .
    Levomecol
  • HY-106597
    Pirlimycin

    		Antibiotic Bacterial Infection
    Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
    Pirlimycin
  • HY-106597A
    Pirlimycin hydrochloride

    		Bacterial Antibiotic Infection
    Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
    Pirlimycin hydrochloride
  • HY-122386
    Kirromycin

    Mocimycin; Delvomycin

    		 Bacterial Antibiotic Infection
    Kirromycin (Mocimycin) is an antibiotic produced by Streptomyces collinus Tu 365. Kirromycin is a bacterial protein synthesis inhibitor that immobilizes elongation factor Tu (EF-Tu) on the elongating ribosome .
    Kirromycin
  • HY-118099
    Florfenicol amine hydrochloride

    		Bacterial Drug Metabolite Infection
    Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases .
    Florfenicol amine hydrochloride
  • HY-14855
    Tedizolid
    10+ Cited Publications

    TR 700; Torezolid; DA-7157

    		 Bacterial Antibiotic Infection
    Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
    Tedizolid
  • HY-147304
    BPH-1086

    		Bacterial Others
    BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome .
    BPH-1086
  • HY-P5637
    Tur1A

    		Bacterial Infection
    Tur1A is an antimicrobial peptide derived from bottlenose dolphins Tursiops truncates. Tur1A inhibits bacterial protein synthesis by binding to ribosomes and blocking the transition from the initiation stage to the extension stage .
    Tur1A
  • HY-P5723
    Api137

    		Bacterial Infection
    Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .
    Api137
  • HY-163331
    Cresomycin

    		Antibiotic Bacterial Infection
    Cresomycin is a bridged macrobicyclic antibiotic that can bind to the bacterial ribosome. Cresomycin exhibits efficacy against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa .
    Cresomycin
  • HY-P5723A
    Api137 TFA

    		Bacterial Infection
    Api137 TFA is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 TFA inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain .
    Api137 TFA
  • HY-B0956
    Paromomycin sulfate
    2 Publications Verification

    Aminosidine sulfate

    		 Antibiotic Parasite Bacterial Infection
    Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
    Paromomycin sulfate
  • HY-139554A
    Zifanocycline TFA

    KBP-7072 TFA

    		 Bacterial Infection
    Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
    Zifanocycline TFA
  • HY-18982
    Anisomycin
    Maximum Cited Publications
    78 Publications Verification

    Flagecidin; Wuningmeisu C

    		 DNA/RNA Synthesis JNK Bacterial Apoptosis Antibiotic Parasite Infection Cancer
    Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system . Anisomycin is a JNK activator, which increases phospho-JNK . Anisomycin is a bacterial antibiotic .
    Anisomycin
  • HY-106597AR
    Pirlimycin hydrochloride (Standard)

    		Bacterial Antibiotic Infection
    Pirlimycin (hydrochloride) (Standard) is the analytical standard of Pirlimycin (hydrochloride). This product is intended for research and analytical applications. Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome .
    Pirlimycin hydrochloride (Standard)
  • HY-14855R
    Tedizolid (Standard)

    		Bacterial Antibiotic Infection
    Tedizolid (Standard) is the analytical standard of Tedizolid. This product is intended for research and analytical applications. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
    Tedizolid (Standard)
  • HY-B1327
    Chlortetracycline hydrochloride
    3 Publications Verification

    7-Chlorotetracycline hydrochloride

    		 Bacterial Antibiotic Parasite Infection Inflammation/Immunology
    Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
    Chlortetracycline hydrochloride
  • HY-B1327A
    Chlortetracycline

    7-Chlorotetracycline

    		 Bacterial Antibiotic Parasite Infection Inflammation/Immunology
    Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
    Chlortetracycline
  • HY-14855S
    Tedizolid-13C,d3

    TR 700-13C,d3; Torezolid-13C,d3; DA-7157-13C,d3

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Tedizolid- 13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
    Tedizolid-13C,d3
  • HY-B0956R
    Paromomycin (sulfate) (Standard)

    		Antibiotic Parasite Bacterial Infection
    Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
    Paromomycin (sulfate) (Standard)
  • HY-17412
    Minocycline hydrochloride
    35+ Cited Publications

    		 Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
    Minocycline hydrochloride
  • HY-17412A
    Minocycline

    		Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
    Minocycline
  • HY-17412R
    Minocycline hydrochloride (Standard)

    		Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Minocycline (hydrochloride) (Standard) is the analytical standard of Minocycline (hydrochloride). This product is intended for research and analytical applications. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
    Minocycline hydrochloride (Standard)
  • HY-W654013
    Minocycline-d7

    		Isotope-Labeled Compounds Apoptosis Potassium Channel Antibiotic Bacterial MDM-2/p53 HIF/HIF Prolyl-Hydroxylase Calcium Channel Infection
    Minocycline-d7 is deuterium labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
    Minocycline-d7
  • HY-B1828AR
    Spectinomycin dihydrochloride pentahydrate (Standard)

    Spectinomycin hydrochloride hydrate (Standard)

    		 Bacterial Antibiotic Infection
    Spectinomycin (dihydrochloride pentahydrate) (Standard) is the analytical standard of Spectinomycin (dihydrochloride pentahydrate). This product is intended for research and analytical applications. Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
    Spectinomycin dihydrochloride pentahydrate (Standard)
  • HY-B1350A
    Fusidic acid sodium salt
    2 Publications Verification

    Sodium fusidate; SQ-16360

    		 Bacterial Antibiotic Interleukin Related Infection Inflammation/Immunology
    Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice .
    Fusidic acid sodium salt

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