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Results for "

copper ion

" in MedChemExpress (MCE) Product Catalog:

27

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10

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6

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2

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2

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Click Chemistry

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1550

    Fluorescent Dye Others
    10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a fluorescent dye for Cu 2+ ion .
    10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515
  • HY-D0813

    Fluorescent Dye Others
    Zincon sodium is an excellent colorimetric reagent for the detection of zinc and copper ions in aqueous solution. Zincon sodium can be used for the determination of zinc, copper, and cobalt ions in metalloproteins .
    Zincon sodium
  • HY-W004563

    Biochemical Assay Reagents Others
    Neocuproine is an organic compound commonly used as a complexing reagent and copper ion detector. It can form stable complexes with copper ions, and can play a catalytic role in certain chemical reactions and analytical methods. In addition, this compound is also widely used in some biomedical fields, such as in the study of copper metabolism disorders and neurodegenerative diseases
    Neocuproine
  • HY-W034953

    Biochemical Assay Reagents Others
    Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.
    Bathocuproine disulfonate disodium
  • HY-D1895A

    Biochemical Assay Reagents Fluorescent Dye Others
    3,5-DiBr-PAESA (sodium) is an ultrasensitive chelating agent used for the determination of silver (I) in water in the absence of interfering ions. It can also be used for the determination of copper (II) .
    3,5-DiBr-PAESA sodium
  • HY-150087

    Fluorescent Dye Others
    Ctrl-CF4-S2 is a chemically modified control probe of the copper probe Copper Fluor-4 (CF4, HY-150086), in which two of the four thioether ligands in CF4 (HY-150086) are replaced with methylene groups. CF4 (HY-150086) is a fluorescent probe used for detecting the presence and distribution of copper ions, whereas Ctrl-CF4-S2 does not respond to copper ions. This allows it to eliminate background signals from copper, thereby helping to determine whether the signals from CF4 (HY-150086) accurately reflect the dynamic changes of copper ions in biological systems
    Ctrl-CF4-S2
  • HY-W111522

    di-Sodium hydrogen phosphite, 98%

    Biochemical Assay Reagents Others
    Sodium phosphite dibasic pentahydrate, 98% is a metal chelating agent used to remove copper ions from water supplies.
    Sodium phosphite dibasic pentahydrate, 98%
  • HY-120743

    Others Metabolic Disease
    Triplin is a copper chelator. Triplin suppresses the toxic effects of excess copper ions on plant root growth. Triplin increases the RNA expression of ERF1. Triplin acts through the ethylene signal transduction pathway. Triplin also is a bacterial pore-former .
    Triplin
  • HY-D0800

    Biochemical Assay Reagents Others
    Chromeazurol S is a compound belonging to the class of azo dyes. It is often used as an indicator in analytical chemistry to detect metal ions such as copper, nickel, and cobalt. Chromeazurol S turns from yellow to blue in the presence of metal ions, allowing them to be detected and quantified. It can be applied to a test strip or added directly to a solution for analysis.
    Mordant Blue 29
  • HY-W034674

    Silver(1+) diethyldithiocarbamate

    Biochemical Assay Reagents Others
    Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
    Silver diethyldithiocarbamate
  • HY-P4531

    Opioid Receptor Neurological Disease
    H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .
    H-Ser-Tyr-OH
  • HY-159151

    Beta-secretase Amyloid-β Neurological Disease
    BACE1-IN-15 (compound 4j) is a potent inhibitor of BACE1 (β-secretase) that can inhibited the copper ion induced Aβ toxicity, with the EC50 of 0.68 μM .
    AChE/Aβ-IN-6
  • HY-D1895

    Fluorescent Dye Others
    3,5-DiBr-PAESA is a supersensitive chelating agent that can be used for silver (I) determination in water in the case of absence of other interfering ions. 3,5-DiBr-PAESA can also be used for copper (II) determination .
    3,5-DiBr-PAESA
  • HY-W013851

    Biochemical Assay Reagents Others
    EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper . EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils . EDTA-OH is able to cross brain-blood barrier .
    EDTA-OH
  • HY-147373

    PROTACs Ligands for E3 Ligase Cancer
    DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research .
    DA-PROTAC
  • HY-141511
    Coppersensor 1
    5+ Cited Publications

    Fluorescent Dye Neurological Disease Cancer
    Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
    Coppersensor 1
  • HY-120420

    Antibiotic Cancer
    N4Py is a pentadentate ligand, that forms a stable complex with metal ions, such as iron, platinum, and copper. N4py mimics the metal binding domains of iron-dependent antibiotics like Bleomycin(HY-17565), forms the DNA-cleaving FeII-N4Py complexes, generates reactive oxygen species (ROS), and causes oxidative damage in cells. N4py can be used in cancer research .
    N4Py
  • HY-138185

    SF 2738A

    Bacterial Apoptosis Cancer
    Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs=6.25 and 100 μg/mL) and fungi (MICs=12.5-100 μg/mL). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC50s=0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC50=56.6 μM) but not MDA-MD-231 breast cancer cells (IC50=>100 μM). Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions.3 Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae in a model of neuronal cell death induced by all-trans retinoic acid.
    Collismycin A
  • HY-B0240
    Disulfiram
    Maximum Cited Publications
    69 Publications Verification

    Tetraethylthiuram disulfide; TETD

    Aldehyde Dehydrogenase (ALDH) Interleukin Related Pyroptosis Apoptosis Cuproptosis Metabolic Disease Cancer
    Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu 2+ increases intracellular ROS levels and induces cuproptosis .
    Disulfiram
  • HY-D0027

    Coumarin 120; AMC

    Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
    7-Amino-4-methylcoumarin
  • HY-16915
    RPR-260243
    1 Publications Verification

    Potassium Channel Cardiovascular Disease
    RPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel . RPR-260243 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    RPR-260243
  • HY-W050154

    Parasite Tyrosinase NF-κB CDK Infection Inflammation/Immunology Cancer
    Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity .
    Kojic acid
  • HY-148418

    Free Fatty Acid Receptor Metabolic Disease
    TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist with a pEC50 of 7.39. TUG-499 exhibits >100-fold selectivity over the related receptors FFA2, FFA3, and the nuclear receptor PPARγ and other diverse receptors, ion channels, and transporters. TUG-499 can be used for the research of type 2 diabetes . TUG-499 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    TUG-499
  • HY-137390A

    Others Cardiovascular Disease Metabolic Disease
    (3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels.
    (3S,5R)-Fluvastatin potassium
  • HY-D0027R

    Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
    7-Amino-4-methylcoumarin (Standard)
  • HY-W050154R

    Parasite Tyrosinase NF-κB CDK Infection Inflammation/Immunology Cancer
    Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
    Kojic acid (Standard)
  • HY-D1850

    Fluorescent Dye Others
    Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-Cy7.5 azide

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