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endogenously found

" in MedChemExpress (MCE) Product Catalog:

35

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1

Biochemical Assay Reagents

3

Peptides

16

Natural
Products

6

Isotope-Labeled Compounds

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153169
    6PPD-Q

    6PPD-Quinone

    		 Endogenous Metabolite Others
    6PPD-Q (6PPD-Quinone) is an endogenous metabolite that can be found in human urine and can also commonly found in the environment .
    6PPD-Q
  • HY-W009444
    5-Methyluridine
    1 Publications Verification

    		 Endogenous Metabolite Others
    5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids.
    5-Methyluridine
  • HY-W008097
    3,3-Dimethylglutaric acid

    		Endogenous Metabolite Metabolic Disease
    3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine .
    3,3-Dimethylglutaric acid
  • HY-W005178
    Octadecanedioic acid

    		Endogenous Metabolite Others
    Octadecanedioic acid, an endogenous metabolite, is a long-chain dicarboxylic acid that has been found in serum free fatty acid profile in Reye syndrome .
    Octadecanedioic acid
  • HY-113315
    3b-Hydroxy-5-cholenoic acid

    		Endogenous Metabolite Metabolic Disease
    3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.
    3b-Hydroxy-5-cholenoic acid
  • HY-B1711
    Norfenefrine

    		Adrenergic Receptor Endocrinology
    Norfenefrine is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence .
    Norfenefrine
  • HY-B1711A
    Norfenefrine hydrochloride

    		Adrenergic Receptor Endocrinology
    Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence .
    Norfenefrine hydrochloride
  • HY-E70236
    CoA-S-S-CoA

    		Endogenous Metabolite Others
    CoA–S-S–CoA is an endogenous metabolite found inP. furiousus. CoA–S-S–CoA is a substrate of NOXA2 .
    CoA-S-S-CoA
  • HY-N10493
    7β,25-Dihydroxycholesterol

    		Endogenous Metabolite Inflammation/Immunology
    7β,25-Dihydroxycholesterol is an endogenous metabolite and is found to act as chemoattractants for immune cells expressing EBI2 .
    7β,25-Dihydroxycholesterol
  • HY-148168
    L-5-Methyluridine

    		Nucleoside Antimetabolite/Analog Others
    L-5-Methyluridine is the L-configuration of 5-Methyluridine (HY-W009444). 5-Methyluridine is an endogenous methylated nucleoside found in human fluids.
    L-5-Methyluridine
  • HY-W009444R
    5-Methyluridine (Standard)

    		Endogenous Metabolite Others
    5-Methyluridine (Standard) is the analytical standard of 5-Methyluridine. This product is intended for research and analytical applications. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids.
    5-Methyluridine (Standard)
  • HY-W013035
    3-Methyl-2-buten-1-ol

    MBO321

    		 Endogenous Metabolite Metabolic Disease
    3-Methyl-2-buten-1-ol (MBO321) is an endogenous metabolite found in pine trees and is used as a fragrance ingredient in cosmetics and detergents .
    3-Methyl-2-buten-1-ol
  • HY-W009444S
    5-Methyluridine-d4

    		Endogenous Metabolite Others
    5-Methyluridine-d4 is the deuterium labeled 5-Methyluridine[1]. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids[2].
    5-Methyluridine-d4
  • HY-W009444S1
    5-Methyluridine-1′-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    5-Methyluridine-1′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
    5-Methyluridine-1′-13C
  • HY-W009444S2
    5-Methyluridine-2′-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    5-Methyluridine-2′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
    5-Methyluridine-2′-13C
  • HY-W009444S3
    5-Methyluridine-3′-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    5-Methyluridine-3′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
    5-Methyluridine-3′-13C
  • HY-W009444S4
    5-Methyluridine-5′-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    5-Methyluridine-5′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
    5-Methyluridine-5′-13C
  • HY-B1711AR
    Norfenefrine (hydrochloride) (Standard)

    		Adrenergic Receptor Endocrinology
    Norfenefrine (hydrochloride) (Standard) is the analytical standard of Norfenefrine (hydrochloride). This product is intended for research and analytical applications. Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence .
    Norfenefrine (hydrochloride) (Standard)
  • HY-133890A
    Tauro-α-muricholic acid sodium

    T-α-MCA sodium

    		 Endogenous Metabolite FXR Others
    Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC50=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .
    Tauro-α-muricholic acid sodium
  • HY-P1179
    Guanylin(human)

    		Guanylate Cyclase Endogenous Metabolite Endocrinology Cancer
    Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism .
    Guanylin(human)
  • HY-P1179A
    Guanylin(human) TFA

    		Guanylate Cyclase Endogenous Metabolite Metabolic Disease
    Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism .
    Guanylin(human) TFA
  • HY-P2831
    Esterase, pig liver
    2 Publications Verification

    CESs

    		 Endogenous Metabolite Metabolic Disease
    Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
    Esterase, pig liver
  • HY-101412
    2-(Methylamino)-1H-purin-6(7H)-one
    1 Publications Verification

    N2-methylguanine

    		 Bacterial DNA/RNA Synthesis Endogenous Metabolite Others
    2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.
    2-(Methylamino)-1H-purin-6(7H)-one
  • HY-B1532
    Anabasine

    (S)-Anabasine; (+)-Anabasine

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical?pesticide?nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine
  • HY-W014928
    Anabasine hydrochloride

    (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride

    		 nAChR Neurological Disease
    Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
    Anabasine hydrochloride
  • HY-W013494
    L-Carnosine
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .
    L-Carnosine
  • HY-W654353
    Tauro-α-muricholic acid-d4-1 sodium

    T-α-MCA-d4-1 sodium

    		 Isotope-Labeled Compounds FXR Endogenous Metabolite Others
    Tauro-α-muricholic acid-d4-1 (sodium) is deuterium labeled Tauro-α-muricholic acid (sodium). Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC50=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .
    Tauro-α-muricholic acid-d4-1 sodium
  • HY-153812
    AST 7062601

    AST070

    		 Others Metabolic Disease
    AST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. Ucp1 refers to uncoupling protein, found in brown and beige fat cells. In mammals, UCP1 oxidizes fatty acids and uncouples ATP production in mitochondria to promote energy dissipation as heat. AST 7062601 can be used to study thermogenic, uncoupled respiration .
    AST 7062601
  • HY-B1532R
    Anabasine (Standard)

    		nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-N6022
    Byakangelicin

    		Others Metabolic Disease
    Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects . Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of agent-agent interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones .
    Byakangelicin
  • HY-B0215A
    Acetylcysteine (extracted from plants)

    N-Acetylcysteine (extracted from plants); N-Acetyl-L-cysteine (extracted from plants); NAC (extracted from plants)

    		 Others Infection Neurological Disease Inflammation/Immunology
    Acetylcysteine (N-Acetylcysteine) extracted from plants is derived from plants and is an antioxidant and mucolytic agent that enhances the reserve of free radical scavengers in cells. It has been reported to prevent neuronal apoptosis while inducing apoptosis in smooth muscle cells. In addition, it inhibits HIV replication and serves as a substrate for microsomal glutathione transferase. This endogenous aminothiol is found in human plasma and urine and is commonly used as a mucolytic agent in clinical settings, usually administered by inhalation.
    Acetylcysteine (extracted from plants)
  • HY-N12970
    14S(15R)-EET

    		Others Others
    14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .
    14S(15R)-EET
  • HY-118816
    11β-Prostaglandin F2α

    11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α

    		 Others Metabolic Disease
    11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
    11β-Prostaglandin F2α
  • HY-113058
    3-Hydroxyoctanoic acid

    		Biochemical Assay Reagents Others
    3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
    3-Hydroxyoctanoic acid
  • HY-126637
    Marasmic acid

    		Bacterial Fungal Infection
    Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
    Marasmic acid

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